TERT Produkte
(Telomerase Reverse Transcriptase (TERT))
Kategorien
Telomerase is a ribonucleoprotein polymerase that maintains telomere ends by addition of the telomere repeat TTAGGG. The enzyme consists of a protein component with reverse transcriptase activity, encoded by this gene, and an RNA component which serves as a template for the telomere repeat. Telomerase expression plays a role in cellular senescence, as it is normally repressed in postnatal somatic cells resulting in progressive shortening of telomeres. Deregulation of telomerase expression in somatic cells may be involved in oncogenesis. Studies in mouse suggest that telomerase also participates in chromosomal repair, since de novo synthesis of telomere repeats may occur at double-stranded breaks. Alternatively spliced variants encoding different isoforms of telomerase reverse transcriptase have been identified\; the full-length sequence of some variants has not been determined. Alternative splicing at this locus is thought to be one mechanism of regulation of telomerase activity. [provided by RefSeq, Jul 2008].
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Ausgewählte TERT Kategorien
TERT Antikörper
High quality antibodies with extensive validation data.
TERT ELISA Kits
Reliable ELISA kits for a wide range of species.
TERT Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene TERT Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IHC, IP, FM
Validierungen
- (20)
- (8)
Kat. Nr.
ABIN6655270
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human, Mouse, Rat
Applikation
WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro)
Validierungen
- (3)
- (5)
Kat. Nr.
ABIN726650
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
ELISA, IHC, FACS
Validierungen
- (6)
Kat. Nr.
ABIN5542472
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene TERT ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
- (1)
Kat. Nr.
ABIN6962962
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
- (1)
Kat. Nr.
ABIN6961943
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
- (1)
Kat. Nr.
ABIN6973670
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene TERT Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Mouse
Source
Escherichia coli (E. coli)
Validierungen
- (1)
Kat. Nr.
ABIN7125334
Menge
50 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
Kat. Nr.
ABIN7396088
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Mouse
Source
Escherichia coli (E. coli)
Validierungen
Kat. Nr.
ABIN7404335
Menge
100 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren TERT Produkten
: "Maternal neglect results in reduced telomerase activity and increased oxidative load in rats." in: Stress (Amsterdam, Netherlands), pp. 1-5, (2020) (PubMed).: "Beneficial Effects of Fermented Papaya Preparation (FPP®) Supplementation on Redox Balance and Aging in a Mouse Model." in: Antioxidants (Basel, Switzerland), Vol. 9, Issue 2, (2020) (PubMed).
: "Ganoderic Acid D Protects Human Amniotic Mesenchymal Stem Cells against Oxidative Stress-Induced Senescence through the PERK/NRF2 Signaling Pathway." in: Oxidative medicine and cellular longevity, Vol. 2020, pp. 8291413, (2020) (PubMed).
: "Telomerase Reverse Transcriptase (TERT) Expression, Telomerase Activity, and Expression of Matrix Metalloproteinases (MMP)-1/-2/-9 in Feline Oral Squamous Cell Carcinoma Cell Lines Associated With ..." in: Frontiers in veterinary science, Vol. 7, pp. 148, (2020) (PubMed).
: "Anti-senescence role of heterozygous fumarate hydratase gene knockout in rat lung fibroblasts in vitro." in: Aging, Vol. 11, Issue 2, pp. 573-589, (2020) (PubMed).
: "Stabilization of Reversed Replication Forks by Telomerase Drives Telomere Catastrophe." in: Cell, Vol. 172, Issue 3, pp. 439-453.e14, (2019) (PubMed).
: "Telomerase level increase is related to n-3 polyunsaturated fatty acid efficacy in first episode schizophrenia: Secondary outcome analysis of the OFFER randomized clinical trial." in: Progress in neuro-psychopharmacology & biological psychiatry, Vol. 83, pp. 142-148, (2019) (PubMed).
: "Generation of an immortalized human choroid endothelial cell line (iChEC-1) using an endothelial cell specific promoter." in: Microvascular research, Vol. 123, pp. 50-57, (2019) (PubMed).
: "Prognostic impact and concordance of TERT promoter mutation and protein expression in matched primary and metastatic cutaneous melanoma." in: British journal of cancer, Vol. 118, Issue 1, pp. 98-105, (2019) (PubMed).
: "Increased expression of NAF1 contributes to malignant phenotypes of glioma cells through promoting protein synthesis and associates with poor patient survival." in: Oncogenesis, Vol. 8, Issue 4, pp. 25, (2019) (PubMed).
Synonyme und alternative Namen zu TERT
telomerase reverse transcriptase (TERT), Telomerase Reverse Transcriptase (trt-1), telomerase reverse transcriptase (Tert), telomerase reverse transcriptase (tert), Tertp (TERT), telomerase reverse transcriptase (CMU_003490), telomerase reverse transcriptase (VDBG_04487), Telomerase catalytic subunit (GL50803_16225), telomerase reverse transcriptase L homeolog (tert.L), ATTERT, chTERT, CMM9, DKCA2, DKCB4, EST2, est2, F5E19.190, F5E19_190, hEST2, hTRT, PFBMFT1, TCS1, tcs1, telomerase, telomerase reverse transcriptase, Tert, tert, tert-A, TP2, tp2, TR, TRT, trt, xTERTBezeichner auf Proteinebene für TERT
- telomerase catalytic subunit
- telomerase-associated protein 2
- Telomerase Reverse Transcriptase family member (trt-1)
- telomerase reverse transcriptase
- hypothetical protein
- telomerase reverse transcriptase beta
- Telomerase catalytic subunit
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