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TET2 Produkte

(Tet Methylcytosine Dioxygenase 2 (TET2))

Kategorien

The protein encoded by this gene is a methylcytosine dioxygenase that catalyzes the conversion of methylcytosine to 5-hydroxymethylcytosine. The encoded protein is involved in myelopoiesis, and defects in this gene have been associated with several myeloproliferative disorders. Two variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2011].

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Ausgewählte TET2 Kategorien

TET2 Antikörper

High quality antibodies with extensive validation data.

TET2 ELISA Kits

Reliable ELISA kits for a wide range of species.

Empfohlene TET2 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB, ELISA, IHC, FACS, ICC
Validierungen
  • (7)
Kat. Nr. ABIN7193624
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human, Mouse, Rat
Applikation WB, IHC
Validierungen
  • (5)
Kat. Nr. ABIN7261632
Menge 200 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, IHC
Validierungen
  • (5)
Kat. Nr. ABIN1513598
Menge 100 μg
Datenblatt Datenblatt

Empfohlene TET2 ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6970599
Menge 96 tests
Datenblatt Datenblatt

Empfohlene TET2 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source HEK-293 Cells
Validierungen
Kat. Nr. ABIN7535260
Menge 50 μg
Datenblatt Datenblatt
Reaktivität Human
Source HEK-293 Cells
Validierungen
Kat. Nr. ABIN7535933
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Source HEK-293 Cells
Validierungen
Kat. Nr. ABIN7535088
Menge 100 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren TET2 Produkten

Lei, Wu, Gu, Ji, Yang: "Differences in DNA Methylation Reprogramming Underlie the Sexual Dimorphism of Behavioral Disorder Caused by Prenatal Stress in Rats." in: Frontiers in neuroscience, Vol. 14, pp. 573107, (2020) (PubMed).

Yu, Liu, Liu, Wang, Liu, Miao, Du, Yang: "Ascorbic acid induces global epigenetic reprogramming to promote meiotic maturation and developmental competence of porcine oocytes." in: Scientific reports, Vol. 8, Issue 1, pp. 6132, (2018) (PubMed).

Tucker, Getchell, McCarthy, Ohman, Sasamoto, Xu, Ko, Gupta, Shafrir, Medina, Lee, MacDonald, Malik, Hasselblatt, Li, Zhang, Kaplan, Murphy, Hirsch, Liu, Matulonis, Terry, Lian, Dinulescu: "Epigenetic Reprogramming Strategies to Reverse Global Loss of 5-Hydroxymethylcytosine, a Prognostic Factor for Poor Survival in High-grade Serous Ovarian Cancer." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 24, Issue 6, pp. 1389-1401, (2018) (PubMed).

Fischer, Miles: "Silencing HIF-1α induces TET2 expression and augments ascorbic acid induced 5-hydroxymethylation of DNA in human metastatic melanoma cells." in: Biochemical and biophysical research communications, Vol. 490, Issue 2, pp. 176-181, (2017) (PubMed).

Wallner, Schröder, Leitão, Berulava, Haak, Beißer, Rahmann, Richter, Manke, Bönisch, Arrigoni, Fröhler, Klironomos, Chen, Rajewsky, Müller, Ebert, Lengauer, Barann, Rosenstiel, Gasparoni, Nordström et al.: "Epigenetic dynamics of monocyte-to-macrophage differentiation. ..." in: Epigenetics & chromatin, Vol. 9, pp. 33, (2016) (PubMed).

Gong, Guo, Niu, Jin, Zhang, Shi, Zhang, Li, Chen, Ma: "Epigenetic silencing of TET2 and TET3 induces an EMT-like process in melanoma." in: Oncotarget, Vol. 8, Issue 1, pp. 315-328, (2016) (PubMed).

Tsai, Li, Chen, Yeh, Huang, Tseng, Fu, Liou, Pan, Huang, Chen, Chang, Ger, Chang: "Reduction of global 5-hydroxymethylcytosine is a poor prognostic factor in breast cancer patients, especially for an ER/PR-negative subtype." in: Breast cancer research and treatment, Vol. 153, Issue 1, pp. 219-34, (2015) (PubMed).

Orr, Haffner, Nelson, Yegnasubramanian, Eberhart: "Decreased 5-hydroxymethylcytosine is associated with neural progenitor phenotype in normal brain and shorter survival in malignant glioma." in: PLoS ONE, Vol. 7, Issue 7, pp. e41036, (2012) (PubMed).

Langemeijer, Kuiper, Berends, Knops, Aslanyan, Massop, Stevens-Linders, van Hoogen, van Kessel, Raymakers, Kamping, Verhoef, Verburgh, Hagemeijer, Vandenberghe, de Witte, van der Reijden, Jansen: "Acquired mutations in TET2 are common in myelodysplastic syndromes." in: Nature genetics, Vol. 41, Issue 7, pp. 838-42, (2009) (PubMed).

Synonyme und alternative Namen zu TET2

tet methylcytosine dioxygenase 2 (TET2), tet methylcytosine dioxygenase 2 (Tet2), Ayu17-449, E130014J05Rik, KIAA1546, MDS, mKIAA1546, RGD1311625

Bezeichner auf Proteinebene für TET2

  • methylcytosine dioxygenase TET2
  • probable methylcytosine dioxygenase TET2
  • tet oncogene family member 2
  • tet oncogene 2
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