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TFPI Produkte

(Tissue Factor Pathway Inhibitor (Lipoprotein-Associated Coagulation Inhibitor) (TFPI))

Kategorien

This gene encodes a protease inhibitor that regulates the tissue factor (TF)-dependent pathway of blood coagulation. The coagulation process initiates with the formation of a factor VIIa-TF complex, which proteolytically activates additional proteases (factors IX and X) and ultimately leads to the formation of a fibrin clot. The product of this gene inhibits the activated factor X and VIIa-TF proteases in an autoregulatory loop. The encoded protein is glycosylated and predominantly found in the vascular endothelium and plasma in both free forms and complexed with plasma lipoproteins. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been confirmed. [provided by RefSeq, Jul 2008].

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Ausgewählte TFPI Kategorien

TFPI Antikörper

High quality antibodies with extensive validation data.

TFPI ELISA Kits

Reliable ELISA kits for a wide range of species.

TFPI Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene TFPI Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Rat
Applikation WB, IHC, IP, ICC
Validierungen
  • (5)
Kat. Nr. ABIN7427348
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, IHC, IP, ICC
Validierungen
  • (3)
Kat. Nr. ABIN7431728
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, IHC, ELISA, IHC (p)
Validierungen
  • (3)
Kat. Nr. ABIN962011
Menge 50 μg
Datenblatt Datenblatt

Empfohlene TFPI ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
  • (1)
Kat. Nr. ABIN367608
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
  • (1)
Kat. Nr. ABIN6960009
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Mouse
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (3)
  • (1)
Kat. Nr. ABIN6960010
Menge 96 tests
Datenblatt Datenblatt

Empfohlene TFPI Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source HEK-293 Cells
Validierungen
  • (2)
Kat. Nr. ABIN7275696
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1322583
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1322581
Menge 10 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren TFPI Produkten

Ranasinghe, Duke, Harvie, McManus: "Kunitz-type protease inhibitor as a vaccine candidate against schistosomiasis mansoni." in: International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases, Vol. 66, pp. 26-32, (2018) (PubMed).

Gamperl, Plattfaut, Freund, Quecke, Theophil, Gieseler: "Extracellular vesicles from malignant effusions induce tumor cell migration: inhibitory effect of LMWH tinzaparin." in: Cell biology international, Vol. 40, Issue 10, pp. 1050-61, (2016) (PubMed).

Wu, Darlington, Cap: "Procoagulant and fibrinolytic activity after polytrauma in rat." in: American journal of physiology. Regulatory, integrative and comparative physiology, Vol. 310, Issue 4, pp. R323-9, (2016) (PubMed).

Gustafson, Shepherd, Miller, Jayachandran: "Age- and sex-specific differences in blood-borne microvesicles from apparently healthy humans." in: Biology of sex differences, Vol. 6, pp. 10, (2015) (PubMed).

Walter, Steinwede, Aly, Reinheckel, Bohling, Maus, Ehlers: "Cathepsin G in Experimental Tuberculosis: Relevance for Antibacterial Protection and Potential for Immunotherapy." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 195, Issue 7, pp. 3325-33, (2015) (PubMed).

Kondo, Ishida, Yasuda, Nakajima, Mori, Tanaka, Mori, Monguchi, Shinohara, Irino, Toh, Rikitake, Kiyomizu, Tomiyama, Yamamoto, Hirata: "Trans-fatty acid promotes thrombus formation in mice by aggravating antithrombogenic endothelial functions via Toll-like receptors." in: Molecular nutrition & food research, Vol. 59, Issue 4, pp. 729-40, (2015) (PubMed).

Wang, Xiao, Wen, Wu, Mao, Zhang, Ma: "Endothelial cell-anchored tissue factor pathway inhibitor regulates tumor metastasis to the lung in mice." in: Molecular carcinogenesis, (2015) (PubMed).

Hansen, Petersen, Lauritzen, Clausen, Grell, Agersø, Sørensen, Hilden, Almholt: "Target-mediated clearance and bio-distribution of a monoclonal antibody against the Kunitz-type protease inhibitor 2 domain of Tissue Factor Pathway Inhibitor." in: Thrombosis research, Vol. 133, Issue 3, pp. 464-71, (2014) (PubMed).

Farid, Mohammed, Afifi, Beltagi: "Tissue factor pathway inhibitor in paediatric patients with nephrotic syndrome." in: SAJCH : the South African journal of child health, Vol. 5, Issue 4, pp. 107-111, (2012) (PubMed).

Marlu, Polack: "Gla-domainless factor Xa: molecular bait to bypass a blocked tenase complex." in: Haematologica, Vol. 97, Issue 8, pp. 1165-72, (2012) (PubMed).

Synonyme und alternative Namen zu TFPI

tissue factor pathway inhibitor (TFPI), tissue factor pathway inhibitor (Tfpi), tissue factor pathway inhibitor a (tfpia), A630013F22Rik, AW552122, EPI, LACI, si:dz44f8.1, TFI, TFPI, TFPI1, tfpib, wu:fb92g01, zgc:152844, zgc:158592

Bezeichner auf Proteinebene für TFPI

  • anti-convertin
  • extrinsic pathway inhibitor
  • tissue factor pathway inhibitor
  • lipoprotein-associated coagulation inhibitor
  • EPI
  • LACI
  • uncharacterized protein LOC100155068
  • LOW QUALITY PROTEIN: tissue factor pathway inhibitor
  • coagulation inhibitor
  • lipoprotein-associated
  • tissue factor pathway inhibitor b
  • tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
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