THC Antikörper
(Tetrahydrocannabinol (THC))
The Wiskott-Aldrich syndrome (WAS) family of proteins share similar domain structure, and are involved in transduction of signals from receptors on the cell surface to the actin cytoskeleton. The presence of a number of different motifs suggests that they are regulated by a number of different stimuli, and interact with multiple proteins. Recent studies have demonstrated that these proteins, directly or indirectly, associate with the small GTPase, Cdc42, known to regulate formation of actin filaments, and the cytoskeletal organizing complex, Arp2/3. Wiskott-Aldrich syndrome is a rare, inherited, X-linked, recessive disease characterized by immune dysregulation and microthrombocytopenia, and is caused by mutations in the WAS gene. The WAS gene product is a cytoplasmic protein, expressed exclusively in hematopoietic cells, which show signalling and cytoskeletal abnormalities in WAS patients. A transcript variant arising as a result of alternative promoter usage, and containing a different 5' UTR sequence, has been described, however, its full-length nature is not known. [provided by RefSeq, Jul 2008].
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Ausgewählte THC Kategorien
THC Antikörper
High quality antibodies with extensive validation data.
Empfohlene THC Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Applikation
ELISA, LF, IA
Validierungen
Kat. Nr.
ABIN7538973
Menge
1 mg
Datenblatt
Datenblatt
Reaktivität
Applikation
ELISA, LF, IA
Validierungen
Kat. Nr.
ABIN7538974
Menge
1 mg
Datenblatt
Datenblatt
Reaktivität
Various Species
Applikation
ELISA, LF
Validierungen
Kat. Nr.
ABIN7384961
Menge
1 mg
Datenblatt
Datenblatt
Synonyme und alternative Namen zu THC
Wiskott-Aldrich syndrome (WAS), IMD2, SCNX, THC, THC1, WASPBezeichner auf Proteinebene für THC
- eczema-thrombocytopenia
- thrombocytopenia 1 (X-linked)
- wiskott-Aldrich syndrome protein
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