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THEMIS Produkte

(Thymocyte Selection Associated (THEMIS))
This gene encodes a protein that plays a regulatory role in both positive and negative T-cell selection during late thymocyte development. The protein functions through T-cell antigen receptor signaling, and is necessary for proper lineage commitment and maturation of T-cells. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2009].

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Ausgewählte THEMIS Kategorien

THEMIS Antikörper

High quality antibodies with extensive validation data.

THEMIS ELISA Kits

Reliable ELISA kits for a wide range of species.

THEMIS Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene THEMIS Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB, ELISA, IHC, IF
Validierungen
  • (3)
Kat. Nr. ABIN7166179
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human, Rat
Applikation WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro), ICC
Validierungen
  • (3)
Kat. Nr. ABIN1714633
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Mouse
Applikation WB, IHC (p)
Validierungen
  • (2)
Kat. Nr. ABIN655135
Menge 400 μL
Datenblatt Datenblatt

Empfohlene THEMIS ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6959950
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Mouse
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6959951
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
Kat. Nr. ABIN6233838
Menge 96 tests
Datenblatt Datenblatt

Empfohlene THEMIS Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN2752947
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Tobacco (Nicotiana tabacum)
Validierungen
Kat. Nr. ABIN3073988
Menge 1 mg
Datenblatt Datenblatt
Reaktivität Mouse
Source Tobacco (Nicotiana tabacum)
Validierungen
Kat. Nr. ABIN3136150
Menge 1 mg
Datenblatt Datenblatt

Neueste Publikationen zu unseren THEMIS Produkten

Paster, Bruger, Katsch, Grégoire, Roncagalli, Fu, Gascoigne, Nika, Cohnen, Feller, Simister, Molder, Cordoba, Dushek, Malissen, Acuto: "A THEMIS:SHP1 complex promotes T-cell survival." in: The EMBO journal, Vol. 34, Issue 3, pp. 393-409, (2015) (PubMed).

Fu, Vallée, Rybakin, McGuire, Ampudia, Brockmeyer, Salek, Fallen, Hoerter, Munshi, Huang, Hu, Fox, Sauer, Acuto, Gascoigne: "Themis controls thymocyte selection through regulation of T cell antigen receptor-mediated signaling." in: Nature immunology, Vol. 10, Issue 8, pp. 848-56, (2009) (PubMed).

Johnson, Aravind, Shulzhenko, Morgun, Choi, Crockford, Lambe, Domaschenz, Kucharska, Zheng, Vinuesa, Lenardo, Goodnow, Cornall, Schwartz: "Themis is a member of a new metazoan gene family and is required for the completion of thymocyte positive selection." in: Nature immunology, Vol. 10, Issue 8, pp. 831-9, (2009) (PubMed).

Lesourne, Uehara, Lee, Song, Li, Pinkhasov, Zhang, Weng, Wildt, Wang, Bosselut, Love: "Themis, a T cell-specific protein important for late thymocyte development." in: Nature immunology, Vol. 10, Issue 8, pp. 840-7, (2009) (PubMed).

Patrick, Oda, Hayakawa, Sato, Eshima, Kirikae, Iemura, Shirai, Abe, Natsume, Sasazuki, Suzuki: "Gasp, a Grb2-associating protein, is critical for positive selection of thymocytes." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 106, Issue 38, pp. 16345-50, (2009) (PubMed).

Synonyme und alternative Namen zu THEMIS

thymocyte selection associated (THEMIS), thymocyte selection associated (Themis), thymocyte selection associated (themis), A430108D01, bA325O24.3, bA325O24.4, BB160712, C6orf190, C6orf207, C9H6ORF190, E430004N04Rik, GASP, Gasp, im:7138580, SPOT, thylex, TSEPA, Tsepa, tsepa

Bezeichner auf Proteinebene für THEMIS

  • thymocyte selection associated
  • thymocyte selection pathway associated
  • GRB2-associated protein
  • protein THEMIS
  • signaling phosphoprotein specific for T cells
  • thymocyte expressed molecule involved in selection
  • thymocyte-expressed molecule involved in selection
  • grb2-associating protein
  • protein thylex
  • thymus lymphocyte exclusively expressed
  • Thymocyte-expressed molecule involved in selection
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