TIRAP Produkte
(Toll-Interleukin 1 Receptor (TIR) Domain Containing Adaptor Protein (TIRAP))
Kategorien
The innate immune system recognizes microbial pathogens through Toll-like receptors (TLRs), which identify pathogen-associated molecular patterns. Different TLRs recognize different pathogen-associated molecular patterns and all TLRs have a Toll-interleukin 1 receptor (TIR) domain, which is responsible for signal transduction. The protein encoded by this gene is a TIR adaptor protein involved in the TLR4 signaling pathway of the immune system. It activates NF-kappa-B, MAPK1, MAPK3 and JNK, which then results in cytokine secretion and the inflammatory response. Alternative splicing of this gene results in several transcript variants\; however, not all variants have been fully described. [provided by RefSeq, Jul 2008].
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Ausgewählte TIRAP Kategorien
TIRAP Antikörper
High quality antibodies with extensive validation data.
TIRAP ELISA Kits
Reliable ELISA kits for a wide range of species.
TIRAP Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene TIRAP Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IHC (p), IHC (fro), ICC
Validierungen
- (8)
Kat. Nr.
ABIN7441712
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IF
Validierungen
- (1)
- (5)
Kat. Nr.
ABIN6149192
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IHC
Validierungen
- (3)
Kat. Nr.
ABIN7172290
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene TIRAP ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6970732
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6960023
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validierungen
Kat. Nr.
ABIN6223712
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene TIRAP Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1322812
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
Kat. Nr.
ABIN7409917
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
Kat. Nr.
ABIN2132191
Menge
50 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren TIRAP Produkten
: "Proximity Ligation Assays for In Situ Detection of Innate Immune Activation: Focus on In Vitro-Transcribed mRNA." in: Molecular therapy. Nucleic acids, Vol. 14, pp. 52-66, (2019) (PubMed).: "Toll-Like Receptor 4 Mediates Methamphetamine-Induced Neuroinflammation through Caspase-11 Signaling Pathway in Astrocytes." in: Frontiers in molecular neuroscience, Vol. 10, pp. 409, (2017) (PubMed).
: "Heterodimer-specific TLR2 stimulation results in divergent functional outcomes in B-cell precursor acute lymphoblastic leukemia." in: European journal of immunology, Vol. 45, Issue 7, pp. 1980-90, (2015) (PubMed).
: "Chemoprevention Activity of Dipyridamole in the MMTV-PyMT Transgenic Mouse Model of Breast Cancer." in: Cancer prevention research (Philadelphia, Pa.), Vol. 6, Issue 5, pp. 437-47, (2013) (PubMed).
: "Phosphatidylinositol 4-phosphate 5-kinase ? facilitates Toll-like receptor 4-mediated microglial inflammation through regulation of the Toll/interleukin-1 receptor domain-containing adaptor protein ..." in: The Journal of biological chemistry, Vol. 288, Issue 8, pp. 5645-59, (2013) (PubMed).
: "Preferential expression and function of Toll-like receptor 3 in human astrocytes." in: Journal of neuroimmunology, Vol. 159, Issue 1-2, pp. 12-9, (2005) (PubMed).
: "Advantages and disadvantages of cytidine deamination." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 172, Issue 11, pp. 6513-8, (2004) (PubMed).
: "Distinct pathways of LPS-induced NF-kappa B activation and cytokine production in human myeloid and nonmyeloid cells defined by selective utilization of MyD88 and Mal/TIRAP." in: Blood, Vol. 103, Issue 6, pp. 2229-37, (2004) (PubMed).
: "TLRs: differential adapter utilization by toll-like receptors mediates TLR-specific patterns of gene expression." in: Molecular interventions, Vol. 3, Issue 8, pp. 466-77, (2004) (PubMed).
: "The expanding family of MyD88-like adaptors in Toll-like receptor signal transduction." in: Molecular immunology, Vol. 41, Issue 6-7, pp. 577-82, (2004) (PubMed).
Synonyme und alternative Namen zu TIRAP
toll-interleukin 1 receptor (TIR) domain containing adaptor protein (tirap), TIR domain containing adaptor protein (TIRAP), toll-interleukin 1 receptor (TIR) domain containing adaptor protein L homeolog (tirap.L), TIR domain containing adaptor protein (Tirap), toll-interleukin 1 receptor (TIR) domain-containing adaptor protein (Tirap), AA407980, BACTS1, C130027E04Rik, mal, Mal, MyD88-2, Tlr4ap, wyatt, WyattBezeichner auf Proteinebene für TIRAP
- MyD88 adapter-like protein
- Toll-interleukin 1 receptor domain-containing adaptor protein
- toll/interleukin-1 receptor domain-containing adapter protein
- TIR domain-containing adaptor protein
- Toll-like receptor adaptor protein
- adapter protein wyatt
- adaptor protein Wyatt
- toll-interleukin 1 receptor domain-containing adaptor protein
- TIR domain-containing adapter protein
- Toll-like receptor 4 adaptor protein
- myD88 adapter-like protein
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