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TLK1 Produkte

(Tousled-Like Kinase 1 (TLK1))

Kategorien

The protein encoded by this gene is a serine/threonine kinase that may be involved in the regulation of chromatin assembly. The encoded protein is only active when it is phosphorylated, and this phosphorylation is cell cycle-dependent, with the maximal activity of this protein coming during S phase. The catalytic activity of this protein is diminished by DNA damage and by blockage of DNA replication. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011].

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Ausgewählte TLK1 Kategorien

TLK1 Antikörper

High quality antibodies with extensive validation data.

TLK1 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene TLK1 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB, IHC (p)
Validierungen
  • (1)
  • (4)
Kat. Nr. ABIN392685
Menge 400 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, ELISA, IHC (p)
Validierungen
  • (4)
Kat. Nr. ABIN564253
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, IF, IP, ICC
Validierungen
  • (1)
  • (3)
Kat. Nr. ABIN2855507
Menge 100 μL
Datenblatt Datenblatt

Empfohlene TLK1 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1322843
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Baculovirus infected Insect Cells
Validierungen
  • (1)
Kat. Nr. ABIN7317054
Menge 50 μg
Datenblatt Datenblatt
Reaktivität Human
Source Insect Cells
Validierungen
Kat. Nr. ABIN5509177
Menge 10 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren TLK1 Produkten

Timiri Shanmugam, Nair, DeBenedetti, Caldito, Abreo, Sunavala-Dossabhoy: "DNA damage response and repair data with pharmacological modulators of Tousled." in: Data in brief, Vol. 7, pp. 1073-7, (2016) (PubMed).

Awate, De Benedetti: "TLK1B mediated phosphorylation of Rad9 regulates its nuclear/cytoplasmic localization and cell cycle checkpoint." in: BMC molecular biology, Vol. 17, pp. 3, (2016) (PubMed).

Takayama, Kokuryo, Yokoyama, Ito, Nagino, Hamaguchi, Senga: "Silencing of Tousled-like kinase 1 sensitizes cholangiocarcinoma cells to cisplatin-induced apoptosis." in: Cancer letters, Vol. 296, Issue 1, pp. 27-34, (2010) (PubMed).

Ewing, Chu, Elisma, Li, Taylor, Climie, McBroom-Cerajewski, Robinson, OConnor, Li, Taylor, Dharsee, Ho, Heilbut, Moore, Zhang, Ornatsky, Bukhman, Ethier, Sheng, Vasilescu, Abu-Farha, Lambert, Duewel et al.: "Large-scale mapping of human protein-protein interactions by mass spectrometry. ..." in: Molecular systems biology, Vol. 3, pp. 89, (2007) (PubMed).

Krause, Jonnalagadda, Gatei, Sillje, Zhou, Nigg, Khanna: "Suppression of Tousled-like kinase activity after DNA damage or replication block requires ATM, NBS1 and Chk1." in: Oncogene, Vol. 22, Issue 38, pp. 5927-37, (2003) (PubMed).

Cabaniols, Ravichandran, Roche: "Phosphorylation of SNAP-23 by the novel kinase SNAK regulates t-SNARE complex assembly." in: Molecular biology of the cell, Vol. 10, Issue 12, pp. 4033-41, (2000) (PubMed).

Synonyme und alternative Namen zu TLK1

tousled like kinase 1 (TLK1), tousled-like kinase 1 (Tlk1), tousled-like kinase 1b (tlk1b), tousled like kinase 1 like (TLK1L), tousled-like kinase 1 (TLK1), serine/threonine-protein kinase TOUSLED (LOC542181), tousled-like kinase 1a (tlk1a), tousled like kinase 1 (tlk1), Serine/threonine-protein kinase tousled-like 1 (tlk-1), tousled like kinase 1 (Tlk1), 4930545J15Rik, DKFZp459L163, fb76h12, fe11e12, PKU-beta, si:dkey-88m1.1, si:dkey-251e16.4, tlk1, TLK1, wu:fb76h12, wu:fe11e12

Bezeichner auf Proteinebene für TLK1

  • SNARE protein kinase SNAK
  • serine threonine protein kinase
  • serine/threonine-protein kinase tousled-like 1
  • pKU-beta protein kinase
  • serine/threonine-protein kinase tousled-like 1-B
  • tousled-like kinase 1
  • tousled-like kinase 1-B
  • LOW QUALITY PROTEIN: serine/threonine-protein kinase tousled-like 1
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