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TLR8 Produkte

(Toll-Like Receptor 8 (TLR8))
The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is predominantly expressed in lung and peripheral blood leukocytes, and lies in close proximity to another family member, TLR7, on chromosome X. [provided by RefSeq, Jul 2008].

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Ausgewählte TLR8 Kategorien

TLR8 Antikörper

High quality antibodies with extensive validation data.

TLR8 ELISA Kits

Reliable ELISA kits for a wide range of species.

TLR8 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene TLR8 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB, IHC, IF
Validierungen
  • (8)
Kat. Nr. ABIN3022015
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, ELISA
Validierungen
  • (1)
  • (3)
Kat. Nr. ABIN526632
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human, Mouse, Rat
Applikation WB, IHC, ELISA, ICC, IF
Validierungen
  • (4)
Kat. Nr. ABIN6265604
Menge 100 μL
Datenblatt Datenblatt

Empfohlene TLR8 ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
  • (1)
Kat. Nr. ABIN6960040
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6970748
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Dog
Analytical Method Quantitative
Validierungen
Kat. Nr. ABIN1059329
Menge 96 tests
Datenblatt Datenblatt

Empfohlene TLR8 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1322888
Menge 25 μg
Datenblatt Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
Kat. Nr. ABIN5569497
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
Kat. Nr. ABIN7395563
Menge 100 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren TLR8 Produkten

Deng, Ge, Liu, Pang, Huang, Peng, Sun, Hou, Zhang: "Impaired expression and function of TLR8 in chronic HBV infection and its association with treatment responses during peg-IFN-α-2a antiviral therapy." in: Clinics and research in hepatology and gastroenterology, (2017) (PubMed).

Huhta, Helminen, Kauppila, Salo, Porvari, Saarnio, Lehenkari, Karttunen: "The Expression of Toll-like Receptors in Normal Human and Murine Gastrointestinal Organs and the Effect of Microbiome and Cancer." in: The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, Vol. 64, Issue 8, pp. 470-82, (2017) (PubMed).

Chauhan: "FcγRIIIa Signaling Modulates Endosomal TLR Responses in Human CD4+T Cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 198, Issue 12, pp. 4596-4606, (2017) (PubMed).

Jeon, Kim, Koh, Chung, Ha: "Pellino-1 confers chemoresistance in lung cancer cells by upregulating cIAP2 through Lys63-mediated polyubiquitination." in: Oncotarget, Vol. 7, Issue 27, pp. 41811-41824, (2016) (PubMed).

Helminen, Huhta, Kauppila, Lehenkari, Saarnio, Karttunen: "Localization of nucleic acid-sensing toll-like receptors in human and mouse pancreas." in: APMIS : acta pathologica, microbiologica, et immunologica Scandinavica, Vol. 125, Issue 2, pp. 85-92, (2016) (PubMed).

Chatillon, Hamieh, Bayeux, Abasq, Fauquembergue, Drouet, Guisier, Latouche, Musette: "Direct Toll-Like Receptor 8 signaling increases the functional avidity of human CD8+ T lymphocytes generated for adoptive T cell therapy strategies." in: Immunity, inflammation and disease, Vol. 3, Issue 1, pp. 1-13, (2015) (PubMed).

Bergstrøm, Aune, Awuh, Kojen, Blix, Ryan, Flo, Mollnes, Espevik, Stenvik: "TLR8 Senses Staphylococcus aureus RNA in Human Primary Monocytes and Macrophages and Induces IFN-β Production via a TAK1-IKKβ-IRF5 Signaling Pathway." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 195, Issue 3, pp. 1100-11, (2015) (PubMed).

Zimmermann, Aguilera, Castellucci, Rossato, Costa, Lunardi, Ostuni, Girolomoni, Natoli, Bazzoni, Tamassia, Cassatella: "Chromatin remodelling and autocrine TNFα are required for optimal interleukin-6 expression in activated human neutrophils." in: Nature communications, Vol. 6, pp. 6061, (2015) (PubMed).

Jamin, Dehoux, Dossier, Fila, Heming, Monteiro, Deschênes: "Toll-like receptor 3 expression and function in childhood idiopathic nephrotic syndrome." in: Clinical and experimental immunology, Vol. 182, Issue 3, pp. 332-45, (2015) (PubMed).

Wang, Eng, Lin, Liu, Chang, Lin: "Functional polymorphisms of TLR8 are associated with hepatitis C virus infection." in: Immunology, Vol. 141, Issue 4, pp. 540-8, (2014) (PubMed).

Synonyme und alternative Namen zu TLR8

toll like receptor 8 (TLR8), toll-like receptor 8 (Tlr8), toll like receptor 8 (Tlr8), toll-like receptor 8 (TLR8), CD288
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