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TMED10 Produkte

(Transmembrane Emp24-Like Trafficking Protein 10 (TMED10))

Kategorien

This gene is a member of the EMP24/GP25L/p24 family and encodes a protein with a GOLD domain. This type I membrane protein is localized to the plasma membrane and golgi cisternae and is involved in vesicular protein trafficking. The protein is also a member of a heteromeric secretase complex and regulates the complex's gamma-secretase activity without affecting its epsilon-secretase activity. Mutations in this gene have been associated with early-onset familial Alzheimer's disease. This gene has a pseudogene on chromosome 8. [provided by RefSeq, Jul 2008].

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Ausgewählte TMED10 Kategorien

TMED10 Antikörper

High quality antibodies with extensive validation data.

TMED10 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene TMED10 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human, Mouse
Applikation WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro), ICC
Validierungen
  • (2)
Kat. Nr. ABIN1386483
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation ELISA, IF, FACS
Validierungen
  • (2)
Kat. Nr. ABIN190858
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Applikation WB
Validierungen
  • (1)
Kat. Nr. ABIN1536747
Menge 400 μL
Datenblatt Datenblatt

Empfohlene TMED10 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
  • (1)
Kat. Nr. ABIN6387259
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
Kat. Nr. ABIN2132195
Menge 20 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren TMED10 Produkten

Chen, Hasegawa, Schmitt-Ulms, Kawarai, Bohm, Katayama, Gu, Sanjo, Glista, Rogaeva, Wakutani, Pardossi-Piquard, Ruan, Tandon, Checler, Marambaud, Hansen, Westaway, St George-Hyslop, Fraser: "TMP21 is a presenilin complex component that modulates gamma-secretase but not epsilon-secretase activity." in: Nature, Vol. 440, Issue 7088, pp. 1208-12, (2006) (PubMed).

Periz, Fortini: "Functional reconstitution of gamma-secretase through coordinated expression of presenilin, nicastrin, Aph-1, and Pen-2." in: Journal of neuroscience research, Vol. 77, Issue 3, pp. 309-22, (2004) (PubMed).

Selkoe: "The cell biology of beta-amyloid precursor protein and presenilin in Alzheimer's disease." in: Trends in cell biology, Vol. 8, Issue 11, pp. 447-53, (1999) (PubMed).

Synonyme und alternative Namen zu TMED10

transmembrane p24 trafficking protein 10 L homeolog (tmed10.L), transmembrane p24 trafficking protein 10 (TMED10), transmembrane p24 trafficking protein 10 (Tmed10), transmembrane p24 trafficking protein 10 (tmed10), 1110014C03Rik, fe06g04, p23, P24(DELTA), p24delta1, S31I125, S31III125, Tmp-21-I, tmp21, TMP21, Tmp21, wu:fb98e10, wu:fe06g04, zgc:85681

Bezeichner auf Proteinebene für TMED10

  • transmembrane protein tmp21
  • 21 kDa transmembrane trafficking protein
  • 21 kDa transmembrane-trafficking protein
  • p24 family protein delta-1
  • p24delta
  • p24delta1
  • transmembrane emp24 domain-containing protein 10
  • transmembrane protein Tmp21
  • transmembrane trafficking protein
  • integral membrane protein Tmp21-I (p23)
  • transmembrane trafficking protein 21
  • p24 delta 1
  • integral membrane protein p23
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