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Topoisomerase I Produkte

(Topoisomerase (DNA) I (TOP1))
This gene encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This enzyme catalyzes the transient breaking and rejoining of a single strand of DNA which allows the strands to pass through one another, thus altering the topology of DNA. This gene is localized to chromosome 20 and has pseudogenes which reside on chromosomes 1 and 22. [provided by RefSeq, Jul 2008].

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Ausgewählte Topoisomerase I Kategorien

Topoisomerase I Antikörper

High quality antibodies with extensive validation data.

Topoisomerase I ELISA Kits

Reliable ELISA kits for a wide range of species.

Topoisomerase I Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene Topoisomerase I Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB, ELISA, IHC (p)
Validierungen
  • (1)
  • (8)
Kat. Nr. ABIN563222
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, IHC, IF, IP
Validierungen
  • (7)
Kat. Nr. ABIN7270850
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, ELISA, IHC, IP, FACS
Validierungen
  • (5)
Kat. Nr. ABIN7127850
Menge 100 μL
Datenblatt Datenblatt

Empfohlene Topoisomerase I ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Rat
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
  • (1)
Kat. Nr. ABIN6960049
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6970752
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Mouse
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6970753
Menge 96 tests
Datenblatt Datenblatt

Empfohlene Topoisomerase I Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1323345
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Mouse
Source Escherichia coli (E. coli)
Validierungen
Kat. Nr. ABIN7413022
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
Kat. Nr. ABIN7396097
Menge 100 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren Topoisomerase I Produkten

Kim, Tan, Liu, Trahair, Liu, Haber, Norris, Marshall, Cheung: "High TDP43 expression is required for TRIM16-induced inhibition of cancer cell growth and correlated with good prognosis of neuroblastoma and breast cancer patients." in: Cancer letters, Vol. 374, Issue 2, pp. 315-23, (2016) (PubMed).

Xu, Chen, Wang, Xu, Yuan, Li, Bai, Xue: "Inhibitory effects of lapachol on rat C6 glioma in vitro and in vivo by targeting DNA topoisomerase I and topoisomerase II." in: Journal of experimental & clinical cancer research : CR, Vol. 35, Issue 1, pp. 178, (2016) (PubMed).

Kim, Rahmanto, Tan, Norris, Haber, Marshall, Cheung: "TRIM16 overexpression induces apoptosis through activation of caspase-2 in cancer cells." in: Apoptosis : an international journal on programmed cell death, Vol. 18, Issue 5, pp. 639-51, (2013) (PubMed).

Kobayashi, Aida, Nagaoka, Begum, Kitawaki, Nakata, Stanlie, Doi, Kato, Okazaki, Shinkura, Muramatsu, Kinoshita, Honjo: "AID-induced decrease in topoisomerase 1 induces DNA structural alteration and DNA cleavage for class switch recombination." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 106, Issue 52, pp. 22375-80, (2010) (PubMed).

Deloukas, Matthews, Ashurst, Burton, Gilbert, Jones, Stavrides, Almeida, Babbage, Bagguley, Bailey, Barlow, Bates, Beard, Beare, Beasley, Bird, Blakey, Bridgeman, Brown, Buck, Burrill, Butler, Carder et al.: "The DNA sequence and comparative analysis of human chromosome 20. ..." in: Nature, Vol. 414, Issue 6866, pp. 865-71, (2002) (PubMed).

Tazi, Rossi, Labourier, Gallouzi, Brunel, Antoine: "DNA topoisomerase I: customs officer at the border between DNA and RNA worlds?" in: Journal of molecular medicine (Berlin, Germany), Vol. 75, Issue 11-12, pp. 786-800, (1998) (PubMed).

Kunze, Yang, Dölberg, Sundarp, Knippers, Richter: "Structure of the human type I DNA topoisomerase gene." in: The Journal of biological chemistry, Vol. 266, Issue 15, pp. 9610-6, (1991) (PubMed).

Sugimoto, Tsukahara, Oh-hara, Isoe, Tsuruo: "Decreased expression of DNA topoisomerase I in camptothecin-resistant tumor cell lines as determined by a monoclonal antibody." in: Cancer research, Vol. 50, Issue 21, pp. 6925-30, (1990) (PubMed).

Synonyme und alternative Namen zu Topoisomerase I

Topoisomerase 1 (Top1), DNA topoisomerase I (top1), DNA topoisomerase I (topA), DNA topoisomerase I (ZMO1193), DNA topoisomerase I (MRAD2831_RS63095), DNA topoisomerase I (Lferr_0016), DNA topoisomerase I (PC1_2015), DNA topoisomerase I (Za10_0136), DNA topoisomerase I (Gbro_0575), DNA topoisomerase I (Dd586_2108), DNA topoisomerase I (Kvar_3044), DNA topoisomerase I (Alvin_2069), DNA topoisomerase I (Dacet_0849), DNA topoisomerase I (Mrub_1615), DNA topoisomerase I (Arnit_2962), DNA topoisomerase I (Ndas_4953), DNA topoisomerase I (Trad_2377), DNA topoisomerase I (Acear_1653), DNA topoisomerase I (Mahau_0844), DNA topoisomerase I (Mesop_4109), DNA topoisomerase I (Thein_1586), DNA topoisomerase I (Theth_0241), DNA topoisomerase I alpha (TOP1ALPHA), DNA topoisomerase 1 (top-1), DNA topoisomerase I (TOP1), topoisomerase (DNA) I (Top1), DNA topoisomerase I (Top1), DNA topoisomerase I, gene 1 L homeolog (top1.1.L), Ab2-086, AI467334, CG6146, D130064I21Rik, Dmel\\CG6146, DNA topoisomerase 1 beta, DNA topoisomerase I alpha, dTopoI, l(1)G0134, l(1)G0201, l(1)G0229, l(1)G0278, l(1)top1, MGO1, MGOUN 1, MTE17.1, MTE17_1, Top-1, TOP1, top1, TOP1BETA, TopI, TOPI, topi, Topo I, TopoI, topo I, topoI, TOPOISOMERASE 1

Bezeichner auf Proteinebene für Topoisomerase I

  • CG6146-PA
  • CG6146-PB
  • CG6146-PC
  • CG6146-PD
  • Top1-PA
  • Top1-PB
  • Top1-PC
  • Top1-PD
  • topoisomerase 1
  • topoisomerase I
  • topoisomerase1
  • type I topoisomerase
  • DNA topoisomerase I
  • DNA topoisomerase 1
  • type I DNA topoisomerase
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