TPSAB1 Produkte
(Tryptase alpha/beta 1 (TPSAB1))
Kategorien
Tryptases comprise a family of trypsin-like serine proteases, the peptidase family S1. Tryptases are enzymatically active only as heparin-stabilized tetramers, and they are resistant to all known endogenous proteinase inhibitors. Several tryptase genes are clustered on chromosome 16p13.3. These genes are characterized by several distinct features. They have a highly conserved 3' UTR and contain tandem repeat sequences at the 5' flank and 3' UTR which are thought to play a role in regulation of the mRNA stability. These genes have an intron immediately upstream of the initiator Met codon, which separates the site of transcription initiation from protein coding sequence. This feature is characteristic of tryptases but is unusual in other genes. The alleles of this gene exhibit an unusual amount of sequence variation, such that the alleles were once thought to represent two separate genes, alpha and beta 1. Beta tryptases appear to be the main isoenzymes expressed in mast cells\; whereas in basophils, alpha tryptases predominate. Tryptases have been implicated as mediators in the pathogenesis of asthma and other allergic and inflammatory disorders. [provided by RefSeq, Jul 2008].
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Ausgewählte TPSAB1 Kategorien
TPSAB1 Antikörper
High quality antibodies with extensive validation data.
TPSAB1 ELISA Kits
Reliable ELISA kits for a wide range of species.
TPSAB1 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene TPSAB1 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, IHC, IP, ICC
Validierungen
- (6)
Kat. Nr.
ABIN7433105
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IHC, IP, ICC
Validierungen
- (6)
Kat. Nr.
ABIN7426172
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IHC, IP, ICC
Validierungen
- (6)
Kat. Nr.
ABIN7428305
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene TPSAB1 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (6)
- (6)
Kat. Nr.
ABIN6574250
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
- (1)
Kat. Nr.
ABIN6960219
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Rat
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
- (1)
Kat. Nr.
ABIN6960221
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene TPSAB1 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Cynomolgus
Source
Escherichia coli (E. coli)
Validierungen
- (1)
Kat. Nr.
ABIN7275682
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1323462
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Baculovirus infected Insect Cells
Validierungen
- (1)
Kat. Nr.
ABIN5855023
Menge
50 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren TPSAB1 Produkten
: "Dengue virus-elicited tryptase induces endothelial permeability and shock." in: The Journal of clinical investigation, Vol. 129, Issue 10, pp. 4180-4193, (2020) (PubMed).: "Localization of cannabinoid receptors CB1, CB2, GPR55, and PPARα in the canine gastrointestinal tract." in: Histochemistry and cell biology, Vol. 150, Issue 2, pp. 187-205, (2018) (PubMed).
: "Altered Expression of IFN-λ2 in Allergic Airway Disorders and Identification of Its Cell Origins." in: Mediators of inflammation, Vol. 2016, pp. 5759496, (2016) (PubMed).
: "Circulating tryptase as a marker for subclinical atherosclerosis in obese subjects." in: PLoS ONE, Vol. 9, Issue 5, pp. e97014, (2015) (PubMed).
: "Peritoneal mast cell degranulation and gastrointestinal recovery in patients undergoing colorectal surgery." in: Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society, Vol. 27, Issue 6, pp. 764-74, (2015) (PubMed).
: "Tryptase and protease-activated receptor-2 stimulate scratching behavior in a murine model of ovalbumin-induced atopic-like dermatitis." in: International immunopharmacology, Vol. 28, Issue 1, pp. 507-12, (2015) (PubMed).
: "Elevated Serum Tryptase and Endothelin in Patients with ST Segment Elevation Myocardial Infarction: Preliminary Report." in: Mediators of inflammation, Vol. 2015, pp. 395173, (2015) (PubMed).
: "Effect of Auricular Acupressure on Uremic Pruritus in Patients Receiving Hemodialysis Treatment: A Randomized Controlled Trial." in: Evidence-based complementary and alternative medicine : eCAM, Vol. 2015, pp. 593196, (2015) (PubMed).
: "Improved liver function and relieved pruritus after 4-phenylbutyrate therapy in a patient with progressive familial intrahepatic cholestasis type 2." in: The Journal of pediatrics, Vol. 164, Issue 5, pp. 1219-1227.e3, (2014) (PubMed).
: "Beetroot (Beta vulgaris L.) extract ameliorates gentamicin-induced nephrotoxicity associated oxidative stress, inflammation, and apoptosis in rodent model." in: Mediators of inflammation, Vol. 2014, pp. 983952, (2014) (PubMed).
Synonyme und alternative Namen zu TPSAB1
tryptase alpha/beta 1 (TPSAB1), tryptase (MCT7), tryptase alpha/beta 1 (tpsab1), tryptase beta 2 (gene/pseudogene) (TPSB2), tryptase alpha/beta 1 (Tpsab1), tryptase beta 2 (Tpsb2), AV011504, Mcp-6, Mcp-7, Mcp6, Mcp7, Mcpt6, Mcpt7, MMCP-6, MMCP-7, PMCT7, rMCP-7, TPS1, TPS2, tpsab1, TPSB1, tryptaseB, tryptaseCBezeichner auf Proteinebene für TPSAB1
- mast cell alpha II tryptase
- mast cell beta I tryptase
- tryptase I
- tryptase alpha II
- tryptase alpha-1
- tryptase alpha/beta-1
- tryptase beta 1
- tryptase beta I
- tryptase beta-1
- tryptase-1
- tryptase-I
- tryptase-III
- tryptase alpha/beta 1
- mast cell tryptase beta II
- mast cell tryptase beta III
- tryptase beta-2
- mast cell protease 7
- mast cell-restricted serine protease 7
- tryptase
- MMCP-7
- tryptase, skin
- mast cell protease 6
- tryptase-2
- rMCP-6
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