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TPX2, Microtubule-Associated, Homolog (Xenopus Laevis) Produkte

(TPX2, Microtubule-Associated, Homolog (Xenopus Laevis) (TPX2))
Spindle assembly factor. Required for normal assembly of mitotic spindles. Required for normal assembly of microtubules during apoptosis. Required for chromatin and/or kinetochore dependent microtubule nucleation. Mediates AURKA localization to spindle microtubules. Activates AURKA by promoting its autophosphorylation and protects the phosphorylated residue against dephosphorylation (By similarity).

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Ausgewählte TPX2, Microtubule-Associated, Homolog (Xenopus Laevis) Kategorien

TPX2, Microtubule-Associated, Homolog (Xenopus Laevis) Antikörper

High quality antibodies with extensive validation data.

TPX2, Microtubule-Associated, Homolog (Xenopus Laevis) ELISA Kits

Reliable ELISA kits for a wide range of species.

TPX2, Microtubule-Associated, Homolog (Xenopus Laevis) Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene TPX2, Microtubule-Associated, Homolog (Xenopus Laevis) Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human, Mouse, Rat
Applikation WB, ELISA, IP, IHC (p), ICC
Validierungen
  • (3)
Kat. Nr. ABIN5711936
Menge 0.1 mg
Datenblatt Datenblatt
Reaktivität Human, Mouse, Rat
Applikation WB, ELISA, IHC, IF, ICC
Validierungen
  • (3)
Kat. Nr. ABIN6261299
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, IP, ICC, FACS, DB
Validierungen
  • (3)
Kat. Nr. ABIN931062
Menge 100 μg
Datenblatt Datenblatt

Empfohlene TPX2, Microtubule-Associated, Homolog (Xenopus Laevis) ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method
Validierungen
Kat. Nr. ABIN1160841
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Mouse
Analytical Method
Validierungen
Kat. Nr. ABIN1160842
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Cow
Analytical Method
Validierungen
Kat. Nr. ABIN1160840
Menge 96 tests
Datenblatt Datenblatt

Empfohlene TPX2, Microtubule-Associated, Homolog (Xenopus Laevis) Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
  • (1)
Kat. Nr. ABIN7125423
Menge 50 μg
Datenblatt Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1323477
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source HEK-293 Cells
Validierungen
  • (2)
Kat. Nr. ABIN2734107
Menge 20 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren TPX2, Microtubule-Associated, Homolog (Xenopus Laevis) Produkten

Hsu, Wang, Lin, Huang, Lai, Liao, Chen: "Adducin-1 is essential for spindle pole integrity through its interaction with TPX2." in: EMBO reports, Vol. 19, Issue 8, (2019) (PubMed).

van Gijn, Wierenga, van den Tempel, Kok, Heijink, Spierings, Foijer, van Vugt, Fehrmann: "TPX2/Aurora kinase A signaling as a potential therapeutic target in genomically unstable cancer cells." in: Oncogene, Vol. 38, Issue 6, pp. 852-867, (2019) (PubMed).

Manukyan, Sargsyan, Parsons, Stukenberg: "P190RhoGAP prevents mitotic spindle fragmentation and is required to activate Aurora A kinase at acentriolar poles." in: Chromosoma, Vol. 127, Issue 3, pp. 375-386, (2019) (PubMed).

Connell, Chen, Jiang, Kuan, Fotovati, Chu, He, Lengyell, Li, Kroll, Li, Goldowitz, Frappart, Ploubidou, Patel, Pilarski, Simpson, Lange, Allan, Maxwell: "HMMR acts in the PLK1-dependent spindle positioning pathway and supports neural development." in: eLife, Vol. 6, (2018) (PubMed).

Park, Kwon, Kim, Lee, Song: "USP35 regulates mitotic progression by modulating the stability of Aurora B." in: Nature communications, Vol. 9, Issue 1, pp. 688, (2018) (PubMed).

Mann, Wadsworth: "Distribution of Eg5 and TPX2 in mitosis: Insight from CRISPR tagged cells." in: Cytoskeleton (Hoboken, N.J.), Vol. 75, Issue 12, pp. 508-521, (2018) (PubMed).

Franciosi, Manandhar, Conti: "FSH Regulates mRNA Translation in Mouse Oocytes and Promotes Developmental Competence." in: Endocrinology, Vol. 157, Issue 2, pp. 872-82, (2016) (PubMed).

Rao, Flores-Rodriguez, Page, Wong, Robinson, Chircop: "The Clathrin-dependent Spindle Proteome." in: Molecular & cellular proteomics : MCP, Vol. 15, Issue 8, pp. 2537-53, (2016) (PubMed).

Mann, Balchand, Wadsworth: "Regulation of Kif15 localization and motility by the C-terminus of TPX2 and microtubule dynamics." in: Molecular biology of the cell, Vol. 28, Issue 1, pp. 65-75, (2016) (PubMed).

Shim, Perez de Castro, Neumayer, Wang, Park, Sanada, Nguyen: "Phosphorylation of targeting protein for Xenopus kinesin-like protein 2 (TPX2) at threonine 72 in spindle assembly." in: The Journal of biological chemistry, Vol. 290, Issue 14, pp. 9122-34, (2015) (PubMed).

Synonyme und alternative Namen zu TPX2, Microtubule-Associated, Homolog (Xenopus Laevis)

TPX2, microtubule nucleation factor (TPX2), TPX2, microtubule-associated (Tpx2), TPX2, microtubule nucleation factor (Tpx2), TPX2, microtubule-associated, homolog (Xenopus laevis) (TPX2), TPX2, microtubule-associated S homeolog (tpx2.S), TPX2, microtubule-associated L homeolog (tpx2.L), 2610005B21Rik, C20orf1, C20orf2, DIL-2, dil-2, DIL2, dil2, FLS353, GD:C20orf1, HCA519, HCTP4, hctp4, p100, REPP86, repp86, TPX2, tpx2

Bezeichner auf Proteinebene für TPX2, Microtubule-Associated, Homolog (Xenopus Laevis)

  • TPX2, microtubule-associated protein homolog
  • TPX2, microtubule-associated, homolog
  • differentially expressed in cancerous and non-cancerous lung cells 2
  • differentially expressed in lung cells
  • hepatocellular carcinoma-associated antigen 519
  • preferentially expressed in colorectal cancer
  • protein fls353
  • restricted expression proliferation associated protein 100
  • restricted expression proliferation-associated protein 100
  • targeting protein for Xklp2
  • TPX2, microtubule-associated, homolog (Xenopus laevis)
  • targeting protein for Xklp2-like
  • TPX2 protein, microtubule-associated
  • targeting protein for Xklp2-B
  • targeting protein for Xklp2-A
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