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TRAFs and NIK-Associated Protein Antikörper

(TRAFs and NIK-Associated Protein (TNAP))
There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific). The first three are located together on chromosome 2, while the tissue non-specific form is located on chromosome 1. The product of this gene is a membrane bound glycosylated enzyme that is not expressed in any particular tissue and is, therefore, referred to as the tissue-nonspecific form of the enzyme. The exact physiological function of the alkaline phosphatases is not known. A proposed function of this form of the enzyme is matrix mineralization\; however, mice that lack a functional form of this enzyme show normal skeletal development. This enzyme has been linked directly to hypophosphatasia, a disorder that is characterized by hypercalcemia and includes skeletal defects. The character of this disorder can vary, however, depending on the specific mutation since this determines age of onset and severity of symptoms. Alternatively spliced transcript variants have been described. [provided by RefSeq, Apr 2010].

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Ausgewählte TRAFs and NIK-Associated Protein Kategorien

TRAFs and NIK-Associated Protein Antikörper

High quality antibodies with extensive validation data.

Empfohlene TRAFs and NIK-Associated Protein Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human, Rat
Applikation ELISA, WB, IHC (p)
Validierungen
  • (4)
Kat. Nr. ABIN3181417
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Dog, Goat, Human, Monkey, Pig, Sheep
Applikation FACS
Validierungen
  • (2)
Kat. Nr. ABIN7013887
Menge 0.1 mg
Datenblatt Datenblatt
Reaktivität Dog, Goat, Human, Monkey, Pig, Sheep
Applikation FACS
Validierungen
  • (2)
Kat. Nr. ABIN7013888
Menge 0.1 mg
Datenblatt Datenblatt

Synonyme und alternative Namen zu TRAFs and NIK-Associated Protein

alkaline phosphatase, liver/bone/kidney (ALPL), alkaline phosphatase, liver/bone/kidney (Alpl), Akp-2, Akp2, AP-TNAP, APTNAP, HOPS, TNAP, TNSALP

Bezeichner auf Proteinebene für TRAFs and NIK-Associated Protein

  • alkaline phosphatase liver/bone/kidney isozyme
  • alkaline phosphatase, tissue-nonspecific isozyme
  • alkaline phosphomonoesterase
  • glycerophosphatase
  • liver/bone/kidney-type alkaline phosphatase
  • tissue-nonspecific ALP
  • alkaline phosphatase 2, liver
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