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TREM2 Produkte

(Triggering Receptor Expressed On Myeloid Cells 2 (TREM2))

Kategorien

This gene encodes a membrane protein that forms a receptor signaling complex with the TYRO protein tyrosine kinase binding protein. The encoded protein functions in immune response and may be involved in chronic inflammation by triggering the production of constitutive inflammatory cytokines. Defects in this gene are a cause of polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy (PLOSL). Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Nov 2012].

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Ausgewählte TREM2 Kategorien

TREM2 Antikörper

High quality antibodies with extensive validation data.

TREM2 ELISA Kits

Reliable ELISA kits for a wide range of species.

TREM2 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene TREM2 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Rat
Applikation WB, IHC, IP, ICC
Validierungen
  • (5)
Kat. Nr. ABIN7443632
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human, Mouse, Pig, Rat
Applikation WB, ELISA, ICC, IHC (p), IF (p), IHC (fro), IF (cc)
Validierungen
  • (3)
  • (4)
Kat. Nr. ABIN749678
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Mouse
Applikation WB, IHC (p)
Validierungen
  • (4)
Kat. Nr. ABIN1539189
Menge 400 μL
Datenblatt Datenblatt

Empfohlene TREM2 ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Rat
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6974840
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Mouse
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6999586
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6960173
Menge 96 tests
Datenblatt Datenblatt

Empfohlene TREM2 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source HEK-293 Cells
Validierungen
  • (3)
Kat. Nr. ABIN7275789
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Source HEK-293 Cells
Validierungen
  • (3)
Kat. Nr. ABIN7275790
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Cynomolgus
Source HEK-293 Cells
Validierungen
  • (2)
Kat. Nr. ABIN7275786
Menge 100 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren TREM2 Produkten

Abdi, Pasbakhsh, Shabani, Nekoonam, Sadeghi, Fathi, Abouzaripour, Mohamed, Zibara, Kashani, Zendedel: "Metformin Therapy Attenuates Pro-inflammatory Microglia by Inhibiting NF-κB in Cuprizone Demyelinating Mouse Model of Multiple Sclerosis." in: Neurotoxicity research, (2021) (PubMed).

Banerjee, Ambler, Keshavan, Paterson, Foiani, Toombs, Heslegrave, Dickson, Fraioli, Groves, Lunn, Fox, Zetterberg, Schott, Werring: "Cerebrospinal Fluid Biomarkers in Cerebral Amyloid Angiopathy." in: Journal of Alzheimer's disease : JAD, Vol. 74, Issue 4, pp. 1189-1201, (2020) (PubMed).

Manich, Gómez-López, Almolda, Villacampa, Recasens, Shrivastava, González, Castellano: "Differential Roles of TREM2+ Microglia in Anterograde and Retrograde Axonal Injury Models." in: Frontiers in cellular neuroscience, Vol. 14, pp. 567404, (2020) (PubMed).

Hall, Agrawal: "Increased TREM-2 expression on the subsets of CD11c+ cells in the lungs and lymph nodes during allergic airway inflammation." in: Scientific reports, Vol. 7, Issue 1, pp. 11853, (2019) (PubMed).

Henjum, Quist-Paulsen, Zetterberg, Blennow, Nilsson, Watne: "CSF sTREM2 in delirium-relation to Alzheimer's disease CSF biomarkers Aβ42, t-tau and p-tau." in: Journal of neuroinflammation, Vol. 15, Issue 1, pp. 304, (2019) (PubMed).

Zhong, Xu, Zhuo, Wang, Wang, Huang, Wang, Gao, Zhu, Sheng, Chen, Wang, Zhu, Can, Marten, Shinohara, Liu, Du, Sun, Wen, Xu, Bu, Chen: "Soluble TREM2 ameliorates pathological phenotypes by modulating microglial functions in an Alzheimer's disease model." in: Nature communications, Vol. 10, Issue 1, pp. 1365, (2019) (PubMed).

Jensen, Bahl, Østergaard, Høgh, Wermuth, Heslegrave, Zetterberg, Heegaard, Hasselbalch, Simonsen: "Exercise as a potential modulator of inflammation in patients with Alzheimer's disease measured in cerebrospinal fluid and plasma." in: Experimental gerontology, Vol. 121, pp. 91-98, (2019) (PubMed).

Nordengen, Kirsebom, Henjum, Selnes, Gísladóttir, Wettergreen, Torsetnes, Grøntvedt, Waterloo, Aarsland, Nilsson, Fladby: "Glial activation and inflammation along the Alzheimer's disease continuum." in: Journal of neuroinflammation, Vol. 16, Issue 1, pp. 46, (2019) (PubMed).

Lee, Daggett, Gu, Jiang, Langfelder, Li, Wang, Zhao, Park, Cooper, Ferando, Mody, Coppola, Xu, Yang: "Elevated TREM2 Gene Dosage Reprograms Microglia Responsivity and Ameliorates Pathological Phenotypes in Alzheimer's Disease Models." in: Neuron, Vol. 97, Issue 5, pp. 1032-1048.e5, (2019) (PubMed).

Zhao, Wu, Li, Jiang, Gui, Liu, Sun, Zhu, Piña-Crespo, Zhang, Zhang, Chen, Bu, An, Huang, Xu: "TREM2 Is a Receptor for β-Amyloid that Mediates Microglial Function." in: Neuron, Vol. 97, Issue 5, pp. 1023-1031.e7, (2019) (PubMed).

Synonyme und alternative Namen zu TREM2

triggering receptor expressed on myeloid cells 2 (TREM2), triggering receptor expressed on myeloid cells 2 (trem2), trem-like transcript 2 protein (LOC100228399), triggering receptor expressed on myeloid cells 2 (Trem2), trem-2, TREM-2, TREM-A1, TREM-B1, TREM2, trem2a, Trem2a, trem2b, Trem2b, trem2c, Trem2c

Bezeichner auf Proteinebene für TREM2

  • triggering receptor expressed on myeloid cells 2
  • triggering receptor expressed on monocytes 2
  • triggering receptor expressed on myeloid cells 2a
  • triggering receptor expressed on myeloid cells 2b
  • triggering receptor expressed on myeloid cells 2c
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