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TREX1 Produkte

(three Prime Repair Exonuclease 1 (TREX1))

Kategorien

This gene encodes a nuclear protein with 3' exonuclease activity. The encoded protein may play a role in DNA repair and serve as a proofreading function for DNA polymerase. Mutations in this gene result in Aicardi-Goutieres syndrome, chilblain lupus, Cree encephalitis, and other diseases of the immune system. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2012].

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Ausgewählte TREX1 Kategorien

TREX1 Antikörper

High quality antibodies with extensive validation data.

TREX1 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene TREX1 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB
Validierungen
  • (2)
  • (8)
Kat. Nr. ABIN524703
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, ELISA, IHC, IP
Validierungen
  • (3)
Kat. Nr. ABIN7172071
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, IHC, IF
Validierungen
  • (3)
Kat. Nr. ABIN6149486
Menge 100 μL
Datenblatt Datenblatt

Empfohlene TREX1 ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6970621
Menge 96 tests
Datenblatt Datenblatt

Empfohlene TREX1 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1323580
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1323578
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
Kat. Nr. ABIN7419013
Menge 100 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren TREX1 Produkten

Takahashi, Loo, Okada, Kamachi, Watanabe, Wakita, Watanabe, Kawamoto, Miyata, Barber, Ohtani, Hara: "Downregulation of cytoplasmic DNases is implicated in cytoplasmic DNA accumulation and SASP in senescent cells." in: Nature communications, Vol. 9, Issue 1, pp. 1249, (2018) (PubMed).

Sakai, Miyazaki, Shin, Kim, Qi, Fariss, Munasinghe, Wang, Kovalchuk, Kothari, Fermaintt, Atkinson, Perrino, Yan, Morse: "DNase-active TREX1 frame-shift mutants induce serologic autoimmunity in mice." in: Journal of autoimmunity, Vol. 81, pp. 13-23, (2017) (PubMed).

Tomicic, Aasland, Nikolova, Kaina, Christmann: "Human three prime exonuclease TREX1 is induced by genotoxic stress and involved in protection of glioma and melanoma cells to anticancer drugs." in: Biochimica et biophysica acta, Vol. 1833, Issue 8, pp. 1832-43, (2013) (PubMed).

Christmann, Tomicic, Aasland, Berdelle, Kaina: "Three prime exonuclease I (TREX1) is Fos/AP-1 regulated by genotoxic stress and protects against ultraviolet light and benzo(a)pyrene-induced DNA damage." in: Nucleic acids research, Vol. 38, Issue 19, pp. 6418-32, (2010) (PubMed).

Höss, Robins, Naven, Pappin, Sgouros, Lindahl: "A human DNA editing enzyme homologous to the Escherichia coli DnaQ/MutD protein." in: The EMBO journal, Vol. 18, Issue 13, pp. 3868-75, (1999) (PubMed).

Mazur, Perrino: "Identification and expression of the TREX1 and TREX2 cDNA sequences encoding mammalian 3'-->5' exonucleases." in: The Journal of biological chemistry, Vol. 274, Issue 28, pp. 19655-60, (1999) (PubMed).

Synonyme und alternative Namen zu TREX1

three prime repair exonuclease 1 (CpipJ_CPIJ012074), three prime repair exonuclease 1 (Tsp_03749), three prime repair exonuclease 1 (TREX1), three prime repair exonuclease 1 (Trex1), 1661, AGS1, AU041952, CRV, DRN3, HERNS, RGD1309596

Bezeichner auf Proteinebene für TREX1

  • three prime repair exonuclease 1
  • 3' repair exonuclease 1
  • 3'-5' exonuclease TREX1
  • DNase III
  • deoxyribonuclease III
  • three prime exonuclease 1
  • trophoblast expressed 1
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