TRIB2 Produkte
(Tribbles Pseudokinase 2 (TRIB2))
Kategorien
This gene encodes one of three members of the Tribbles family. The Tribbles members share a Trb domain, which is homologous to protein serine-threonine kinases, but lacks the active site lysine and probably lacks a catalytic function. The Tribbles proteins interact and modulate the activity of signal transduction pathways in a number of physiological and pathological processes. This Tribbles member induces apoptosis of cells mainly of the hematopoietic origin. It has been identified as a protein up-regulated by inflammatory stimuli in myeloid (THP-1) cells, and also as an oncogene that inactivates the transcription factor C/EBPalpha (CCAAT/enhancer-binding protein alpha) and causes acute myelogenous leukemia. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2009].
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Ausgewählte TRIB2 Kategorien
TRIB2 Antikörper
High quality antibodies with extensive validation data.
TRIB2 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene TRIB2 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IHC (p), RNAi
Validierungen
- (3)
- (6)
Kat. Nr.
ABIN565396
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro)
Validierungen
- (3)
Kat. Nr.
ABIN716546
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IHC (p), FACS
Validierungen
- (3)
Kat. Nr.
ABIN652876
Menge
400 μL
Datenblatt
Datenblatt
Empfohlene TRIB2 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
Kat. Nr.
ABIN6209170
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene TRIB2 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
- (1)
Kat. Nr.
ABIN1323589
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Baculovirus infected Insect Cells
Validierungen
- (1)
Kat. Nr.
ABIN7198335
Menge
50 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Tobacco (Nicotiana tabacum)
Validierungen
Kat. Nr.
ABIN3074737
Menge
1 mg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren TRIB2 Produkten
: "TRIB2 inhibits Wnt/?-Catenin/TCF4 signaling through its associated ubiquitin E3 ligases, ?-TrCP, COP1 and Smurf1, in liver cancer cells." in: FEBS letters, Vol. 588, Issue 23, pp. 4334-41, (2014) (PubMed).: "Enhanced macrophage tribbles-1 expression in murine experimental atherosclerosis." in: Biology, Vol. 1, Issue 1, pp. 43-57, (2014) (PubMed).
: "Impaired phosphorylation and ubiquitination by p70 S6 kinase (p70S6K) and Smad ubiquitination regulatory factor 1 (Smurf1) promote tribbles homolog 2 (TRIB2) stability and carcinogenic property in ..." in: The Journal of biological chemistry, Vol. 288, Issue 47, pp. 33667-81, (2013) (PubMed).
: "Ubiquitin E3 ligase SCF(?-TRCP) regulates TRIB2 stability in liver cancer cells." in: Biochemical and biophysical research communications, Vol. 441, Issue 3, pp. 555-9, (2013) (PubMed).
Synonyme und alternative Namen zu TRIB2
tribbles pseudokinase 2 (TRIB2), tribbles pseudokinase 2 (trib2), tribbles pseudokinase 2 S homeolog (trib2.S), tribbles pseudokinase 2 (Trib2), AW319517, c5fw, C5FW, gs3955, GS3955, RGD1564451, TRB-2, Trb2, trb2, TRB2, TRIB2, xtrb2, XtrblBezeichner auf Proteinebene für TRIB2
- tribbles homolog 2 (Drosophila)
- tribbles homolog 2-like
- tribbles homolog 2
- serine/threonine protein kinase
- tribbles-like protein 2
- TRB-2
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