TRIM5 Produkte
(Tripartite Motif Containing 5 (TRIM5))
Kategorien
The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein forms homo-oligomers via the coilel-coil region and localizes to cytoplasmic bodies. It appears to function as a E3 ubiquitin-ligase and ubiqutinates itself to regulate its subcellular localization. It may play a role in retroviral restriction. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Dec 2009].
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Ausgewählte TRIM5 Kategorien
TRIM5 Antikörper
High quality antibodies with extensive validation data.
TRIM5 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene TRIM5 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IHC
Validierungen
- (7)
Kat. Nr.
ABIN184983
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB
Validierungen
- (6)
Kat. Nr.
ABIN2778419
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IHC
Validierungen
- (3)
- (3)
Kat. Nr.
ABIN969443
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene TRIM5 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
Kat. Nr.
ABIN6211786
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene TRIM5 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1323702
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1323704
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
Kat. Nr.
ABIN7420255
Menge
100 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren TRIM5 Produkten
: "Stabilized human TRIM5α protects human T cells from HIV-1 infection." in: Molecular therapy : the journal of the American Society of Gene Therapy, Vol. 22, Issue 6, pp. 1084-95, (2014) (PubMed).: "Type I interferon responses in rhesus macaques prevent SIV infection and slow disease progression. ..." in: Nature, Vol. 511, Issue 7511, pp. 601-5, (2014) (PubMed).
: "Determinants of the higher order association of the restriction factor TRIM5alpha and other tripartite motif (TRIM) proteins." in: The Journal of biological chemistry, Vol. 286, Issue 32, pp. 27959-70, (2011) (PubMed).
: "Restriction of foamy viruses by primate Trim5alpha." in: Journal of virology, Vol. 82, Issue 11, pp. 5429-39, (2008) (PubMed).
: "The design of artificial retroviral restriction factors." in: Virology, Vol. 365, Issue 2, pp. 302-14, (2007) (PubMed).
: "All three variable regions of the TRIM5alpha B30.2 domain can contribute to the specificity of retrovirus restriction." in: Journal of virology, Vol. 80, Issue 17, pp. 8554-65, (2006) (PubMed).
: "Retrovirus restriction by TRIM5alpha variants from Old World and New World primates." in: Journal of virology, Vol. 79, Issue 7, pp. 3930-7, (2005) (PubMed).
: "Cyclophilin A is required for TRIM5{alpha}-mediated resistance to HIV-1 in Old World monkey cells." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 102, Issue 41, pp. 14849-53, (2005) (PubMed).
: "The human and African green monkey TRIM5alpha genes encode Ref1 and Lv1 retroviral restriction factor activities." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 101, Issue 29, pp. 10780-5, (2004) (PubMed).
: "The cytoplasmic body component TRIM5alpha restricts HIV-1 infection in Old World monkeys." in: Nature, Vol. 427, Issue 6977, pp. 848-53, (2004) (PubMed).
Synonyme und alternative Namen zu TRIM5
tripartite motif containing 5 (TRIM5), tripartite motif-containing 5 (Trim5), EG667823, Gm8833, RGD1304579, RNF88, TRIM5, TRIM5alphaBezeichner auf Proteinebene für TRIM5
- tripartite motif-containing 5
- TRIM5alpha
- tripartite motif-containing 5 alpha
- tripartite motif-containing protein 5
- tri-partite motif protein 5
- ring finger protein 88
- tripartite motif containing 5 transcript variant iota
- tripartite motif containing 5 transcript variant kappa
- tripartite motif protein TRIM5
- tripartite motif-containing protein 5 isoform alpha
- TRIM5 alpha
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