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TRPC6 Produkte

(Transient Receptor Potential Cation Channel, Subfamily C, Member 6 (TRPC6))
The protein encoded by this gene forms a receptor-activated calcium channel in the cell membrane. The channel is activated by diacylglycerol and is thought to be under the control of a phosphatidylinositol second messenger system. Activation of this channel occurs independently of protein kinase C and is not triggered by low levels of intracellular calcium. Defects in this gene are a cause of focal segmental glomerulosclerosis 2 (FSGS2). [provided by RefSeq, Mar 2009].

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Ausgewählte TRPC6 Kategorien

TRPC6 Antikörper

High quality antibodies with extensive validation data.

TRPC6 ELISA Kits

Reliable ELISA kits for a wide range of species.

TRPC6 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene TRPC6 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB, IHC, IP, ICC
Validierungen
  • (7)
Kat. Nr. ABIN7441304
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, IHC
Validierungen
  • (4)
Kat. Nr. ABIN6149580
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human, Rat
Applikation WB, IHC (p)
Validierungen
  • (1)
  • (4)
Kat. Nr. ABIN3044146
Menge 100 μg
Datenblatt Datenblatt

Empfohlene TRPC6 ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6960122
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
Kat. Nr. ABIN5659481
Menge 96 tests
Datenblatt Datenblatt

Empfohlene TRPC6 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1323826
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
Kat. Nr. ABIN7408279
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Mouse
Source Tobacco (Nicotiana tabacum)
Validierungen
Kat. Nr. ABIN3135362
Menge 1 mg
Datenblatt Datenblatt

Neueste Publikationen zu unseren TRPC6 Produkten

Wang, Wang, Li: "TRPC1/TRPC3 channels mediate lysophosphatidylcholine-induced apoptosis in cultured human coronary artery smooth muscles cells." in: Oncotarget, Vol. 7, Issue 32, pp. 50937-50951, (2018) (PubMed).

Alonso-González, Cabo, San José, Gago, Suazo, García-Suárez, Cobo, Vega: "Human Digital Meissner Corpuscles Display Immunoreactivity for the Multifunctional Ion Channels Trpc6 and Trpv4." in: Anatomical record (Hoboken, N.J. : 2007), Vol. 300, Issue 6, pp. 1022-1031, (2018) (PubMed).

Wajdner, Farrington, Barnard, Peachell, Schnackenberg, Marino, Xu, Affleck, Begg, Seward: "Orai and TRPC channel characterization in FcεRI-mediated calcium signaling and mediator secretion in human mast cells." in: Physiological reports, Vol. 5, Issue 5, (2017) (PubMed).

Álvarez-Miguel, Cidad, Pérez-García, López-López: "Differences in TRPC3 and TRPC6 channels assembly in mesenteric vascular smooth muscle cells in essential hypertension." in: The Journal of physiology, (2016) (PubMed).

Takada, Furuya, Sokabe: "Mechanosensitive ATP release from hemichannels and Ca²⁺ influx through TRPC6 accelerate wound closure in keratinocytes." in: Journal of cell science, Vol. 127, Issue Pt 19, pp. 4159-71, (2014) (PubMed).

Anderson, Kim, Hagmann, Benzing, Dryer: "Opposing effects of podocin on the gating of podocyte TRPC6 channels evoked by membrane stretch or diacylglycerol." in: American journal of physiology. Cell physiology, Vol. 305, Issue 3, pp. C276-89, (2013) (PubMed).

Kim, Anderson, Wilson, Hagmann, Benzing, Dryer: "NOX2 interacts with podocyte TRPC6 channels and contributes to their activation by diacylglycerol: essential role of podocin in formation of this complex." in: American journal of physiology. Cell physiology, Vol. 305, Issue 9, pp. C960-71, (2013) (PubMed).

Li, Ding, Lopez, Takeshima, Ma, Allen, Eltit: "Impaired Orai1-mediated resting Ca2+ entry reduces the cytosolic [Ca2+] and sarcoplasmic reticulum Ca2+ loading in quiescent junctophilin 1 knock-out myotubes." in: The Journal of biological chemistry, Vol. 285, Issue 50, pp. 39171-9, (2010) (PubMed).

Ding, He, Zhou, Cheng, Yao, Lu, Cai, Jin, Dong, Xu, Wang: "Essential role of TRPC6 channels in G2/M phase transition and development of human glioma." in: Journal of the National Cancer Institute, Vol. 102, Issue 14, pp. 1052-68, (2010) (PubMed).

Potier, Gonzalez, Motiani, Abdullaev, Bisaillon, Singer, Trebak: "Evidence for STIM1- and Orai1-dependent store-operated calcium influx through ICRAC in vascular smooth muscle cells: role in proliferation and migration." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 23, Issue 8, pp. 2425-37, (2009) (PubMed).

Synonyme und alternative Namen zu TRPC6

transient receptor potential cation channel subfamily C member 6 (TRPC6), transient receptor potential cation channel, subfamily C, member 6 (Trpc6), transient receptor potential cation channel, subfamily C, member 6a (trpc6a), transient receptor potential cation channel subfamily C member 6 (Trpc6), transient receptor potential cation channel subfamily C member 6 (trpc6), AV025995, bZ1P14.9, FSGS2, LLHWJM002, LLHWJM003, LLHWJM004, mtrp6, si:rp71-1p14.9, TRP-6, TRP6, trp6, trpc6, Trrp6

Bezeichner auf Proteinebene für TRPC6

  • TRP-6
  • short transient receptor potential channel 6
  • transient receptor protein 6
  • calcium entry channel
  • transient receptor potential cation channel, subfamily C, member 6
  • transient receptor potential channel subfamily C member 6
  • short transient receptor potential channel 6-like
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