TRPM2 Produkte
(Transient Receptor Potential Cation Channel, Subfamily M, Member 2 (TRPM2))
Kategorien
The protein encoded by this gene is a calcium-permeable cation channel that is regulated by free intracellular ADP-ribose. The encoded protein is activated by oxidative stress and confers susceptibility to cell death. Several alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known. [provided by RefSeq, Jul 2008].
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Ausgewählte TRPM2 Kategorien
TRPM2 Antikörper
High quality antibodies with extensive validation data.
TRPM2 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene TRPM2 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
IHC, WB, ELISA, IF
Validierungen
- (6)
Kat. Nr.
ABIN7172859
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
IHC, WB, ELISA
Validierungen
- (3)
Kat. Nr.
ABIN7172857
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Guinea Pig, Human, Mouse, Rat
Applikation
IHC, WB, IHC (p)
Validierungen
- (3)
Kat. Nr.
ABIN490062
Menge
50 μg
Datenblatt
Datenblatt
Empfohlene TRPM2 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Insect Cells
Validierungen
Kat. Nr.
ABIN3096095
Menge
1 mg
Datenblatt
Datenblatt
Reaktivität
Mouse
Source
Escherichia coli (E. coli)
Validierungen
Kat. Nr.
ABIN3127490
Menge
1 mg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Tobacco (Nicotiana tabacum)
Validierungen
Kat. Nr.
ABIN3110954
Menge
1 mg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren TRPM2 Produkten
: "Novel CaM-binding motif in its NudT9H domain contributes to temperature sensitivity of TRPM2." in: Biochimica et biophysica acta. Molecular cell research, (2018) (PubMed).: "Paradoxical lower sensitivity of Locus Coeruleus than Substantia Nigra pars compacta neurons to acute actions of rotenone." in: Experimental neurology, Vol. 287, Issue Pt 1, pp. 34-43, (2016) (PubMed).
: "The role of TRPM2 in hydrogen peroxide-induced expression of inflammatory cytokine and chemokine in rat trigeminal ganglia." in: Neuroscience, Vol. 297, pp. 160-9, (2015) (PubMed).
: "ADP-ribose/TRPM2-mediated Ca2+ signaling is essential for cytolytic degranulation and antitumor activity of natural killer cells." in: Scientific reports, Vol. 5, pp. 9482, (2015) (PubMed).
: "The enzymatic activities of CD38 enhance CLL growth and trafficking: implications for therapeutic targeting." in: Leukemia, Vol. 29, Issue 2, pp. 356-68, (2015) (PubMed).
: "TNF-α-mediated caspase-8 activation induces ROS production and TRPM2 activation in adult ventricular myocytes." in: Cardiovascular research, Vol. 103, Issue 1, pp. 90-9, (2014) (PubMed).
: "Oxidative stress increases pulmonary vascular permeability in diabetic rats through activation of transient receptor potential melastatin 2 channels." in: Microcirculation (New York, N.Y. : 1994), Vol. 21, Issue 8, pp. 754-60, (2014) (PubMed).
: "Structure-activity relationship of adenosine 5'-diphosphoribose at the transient receptor potential melastatin 2 (TRPM2) channel: rational design of antagonists." in: Journal of medicinal chemistry, Vol. 56, Issue 24, pp. 10079-102, (2013) (PubMed).
: "TRPM2 cation channels modulate T cell effector functions and contribute to autoimmune CNS inflammation." in: PLoS ONE, Vol. 7, Issue 10, pp. e47617, (2012) (PubMed).
: "Expression and functional properties of TRPM2 channels in dopaminergic neurons of the substantia nigra of the rat." in: Journal of neurophysiology, Vol. 106, Issue 6, pp. 2865-75, (2011) (PubMed).
Synonyme und alternative Namen zu TRPM2
transient receptor potential cation channel subfamily M member 2 (TRPM2), transient receptor potential cation channel, subfamily M, member 2 (Trpm2), transient receptor potential cation channel, subfamily M, member 2 (trpm2), transient receptor potential cation channel subfamily C member 7 (TRPC7), transient receptor potential cation channel subfamily M member 2 (trpm2), transient receptor potential cation channel subfamily M member 2 (Trpm2), 9830168K16Rik, C79133, EREG1, KNP3, LTRPC2, NUDT9H, NUDT9L1, si:ch73-263b18.1, Trp7, TRPC7, TRPM2, Trpm2-predicted, Trrp7Bezeichner auf Proteinebene für TRPM2
- LTrpC-2
- estrogen-responsive element-associated gene 1 protein
- long transient receptor potential channel 2
- transient receptor potential cation channel subfamily M member 2
- transient receptor potential channel 7
- transient receptor potential melastatin family 2
- transient receptor potential cation channel, subfamily M, member 2
- transient receptor potential cation channel, subfamily C, member 7
- transient receptor potential cation channel, subfamily C, member 7-like
- transient receptor potential cation channel subfamily M member 2-like
- transient receptor protein 7
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