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TSPO Produkte

(Peripheral-Type Benzodiazepine Receptor (TSPO))

Kategorien

Present mainly in the mitochondrial compartment of peripheral tissues, the protein encoded by this gene interacts with some benzodiazepines and has different affinities than its endogenous counterpart. The protein is a key factor in the flow of cholesterol into mitochondria to permit the initiation of steroid hormone synthesis. Alternatively spliced transcript variants have been reported\; one of the variants lacks an internal exon and is considered non-coding, and the other variants encode the same protein. [provided by RefSeq, Feb 2012].

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Ausgewählte TSPO Kategorien

TSPO Antikörper

High quality antibodies with extensive validation data.

TSPO ELISA Kits

Reliable ELISA kits for a wide range of species.

TSPO Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene TSPO Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Mouse
Applikation WB, ELISA, IHC, FACS
Validierungen
  • (1)
  • (11)
Kat. Nr. ABIN570960
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, ELISA, IHC, IP, IF, FACS
Validierungen
  • (6)
Kat. Nr. ABIN7127858
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, ELISA, IHC, IF, FACS
Validierungen
  • (8)
Kat. Nr. ABIN185697
Menge 100 μg
Datenblatt Datenblatt

Empfohlene TSPO ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Mouse
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6969216
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6958481
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN1572930
Menge 96 tests
Datenblatt Datenblatt

Empfohlene TSPO Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1323951
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
Kat. Nr. ABIN7399829
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Source Tobacco (Nicotiana tabacum)
Validierungen
Kat. Nr. ABIN3074824
Menge 1 mg
Datenblatt Datenblatt

Neueste Publikationen zu unseren TSPO Produkten

Hieu Tran, Park, Park, Kwon, Kang, Ho Jung, Chang, Chul Lee, Lee, Kang, Kim: "Synthesis and evaluation of novel potent TSPO PET ligands with 2-phenylpyrazolo[1,5-a]pyrimidin-3-yl acetamide." in: Bioorganic & medicinal chemistry, Vol. 27, Issue 18, pp. 4069-4080, (2019) (PubMed).

Foss, Liu, Mease, Wang, Pasricha, Pomper: "Imaging Macrophage Accumulation in a Murine Model of Chronic Pancreatitis with (125)I-Iodo-DPA-713 SPECT/CT." in: Journal of nuclear medicine : official publication, Society of Nuclear Medicine, Vol. 58, Issue 10, pp. 1685-1690, (2017) (PubMed).

Zhou, Frabutt, Moremen, Zheng: "ERManI (Endoplasmic Reticulum Class I α-Mannosidase) Is Required for HIV-1 Envelope Glycoprotein Degradation via Endoplasmic Reticulum-associated Protein Degradation Pathway." in: The Journal of biological chemistry, Vol. 290, Issue 36, pp. 22184-92, (2015) (PubMed).

Buck, McKinley, Fu, Abel, Thompson, Chambless, Watchmaker, Harty, Cooper, Manning: "Preclinical TSPO Ligand PET to Visualize Human Glioma Xenotransplants: A Preliminary Study." in: PLoS ONE, Vol. 10, Issue 10, pp. e0141659, (2015) (PubMed).

Zhou, Dang, Zheng: "The mitochondrial translocator protein, TSPO, inhibits HIV-1 envelope glycoprotein biosynthesis via the endoplasmic reticulum-associated protein degradation pathway." in: Journal of virology, Vol. 88, Issue 6, pp. 3474-84, (2014) (PubMed).

Bae, Shim, Balu, Kim, Yu: "Translocator protein 18 kDa negatively regulates inflammation in microglia." in: Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology, Vol. 9, Issue 3, pp. 424-37, (2014) (PubMed).

Taylor, Allen, Graham: "Targeting mitochondrial 18 kDa translocator protein (TSPO) regulates macrophage cholesterol efflux and lipid phenotype." in: Clinical science (London, England : 1979), Vol. 127, Issue 10, pp. 603-13, (2014) (PubMed).

Wu, Gallo: "The 18-kDa translocator protein (TSPO) disrupts mammary epithelial morphogenesis and promotes breast cancer cell migration." in: PLoS ONE, Vol. 8, Issue 8, pp. e71258, (2013) (PubMed).

Morgan, Cheepala, Wang, Neale, Adachi, Nachagari, Leggas, Zhao, Boyd, Venkataramanan, Schuetz: "Deregulated hepatic metabolism exacerbates impaired testosterone production in Mrp4-deficient mice." in: The Journal of biological chemistry, Vol. 287, Issue 18, pp. 14456-66, (2012) (PubMed).

Joo, Lee, Lim, Lee, Choi, Cho, Park, Ryoo, Park, Jeon: "Peripheral benzodiazepine receptor regulates vascular endothelial activations via suppression of the voltage-dependent anion channel-1." in: FEBS letters, Vol. 586, Issue 9, pp. 1349-55, (2012) (PubMed).

Synonyme und alternative Namen zu TSPO

peripheral-type benzodiazepine receptor (LOC732875), peripheral-type benzodiazepine receptor (MAV_3896), Peripheral-type benzodiazepine receptor (xccb100_2086), putative peripheral-type benzodiazepine receptor (Smp_102510), peripheral-type benzodiazepine receptor (Sros_1911), translocator protein (tspo), translocator protein homolog (LOC100280949), hypothetical protein (PGTG_16395), translocator protein (TSPO), translocator protein (Tspo), BPBS, BZRP, Bzrp, DBI, IBP, LOC732875, LOC100136652, LOC100280949, MBR, mDRC, PBR, PBS, pk18, PKBS, PTBR, Ptbzr, PTBZR02, RATPTBZR02, TSPO, Tspo1

Bezeichner auf Proteinebene für TSPO

  • peripheral-type benzodiazepine receptor
  • Peripheral-type benzodiazepine receptor
  • translocator protein
  • PKBS
  • benzodiazepine receptor, peripheral
  • isoquinoline-binding protein
  • mitochondrial benzodiazepine receptor
  • Benzodiazepin receptor (peripheral)
  • PBR
  • benzodiazepine peripheral binding site
  • peripheral benzodiazepine receptor
  • IBP
  • benzodiazepine receptor (peripheral)
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