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TUBA1A Produkte

(Tubulin, alpha 1a (Tuba1a))
Microtubules of the eukaryotic cytoskeleton perform essential and diverse functions and are composed of a heterodimer of alpha and beta tubulins. The genes encoding these microtubule constituents belong to the tubulin superfamily, which is composed of six distinct families. Genes from the alpha, beta and gamma tubulin families are found in all eukaryotes. The alpha and beta tubulins represent the major components of microtubules, while gamma tubulin plays a critical role in the nucleation of microtubule assembly. There are multiple alpha and beta tubulin genes, which are highly conserved among species. This gene encodes alpha tubulin and is highly similar to the mouse and rat Tuba1 genes. Northern blotting studies have shown that the gene expression is predominantly found in morphologically differentiated neurologic cells. This gene is one of three alpha-tubulin genes in a cluster on chromosome 12q. Mutations in this gene cause lissencephaly type 3 (LIS3) - a neurological condition characterized by microcephaly, mental retardation, and early-onset epilepsy and caused by defective neuronal migration. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2012].

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Ausgewählte TUBA1A Kategorien

TUBA1A Antikörper

High quality antibodies with extensive validation data.

TUBA1A ELISA Kits

Reliable ELISA kits for a wide range of species.

TUBA1A Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene TUBA1A Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB, IF, IHC (p), ICC
Validierungen
  • (1)
  • (7)
Kat. Nr. ABIN2856707
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation ELISA, WB, IHC, IF, IP, FACS
Validierungen
  • (6)
Kat. Nr. ABIN7127861
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation ELISA, WB, IF
Validierungen
  • (1)
  • (4)
Kat. Nr. ABIN521658
Menge 100 μg
Datenblatt Datenblatt

Empfohlene TUBA1A ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6960236
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Monkey
Analytical Method Quantitative Sandwich ELISA
Validierungen
Kat. Nr. ABIN6200875
Menge 96 tests
Datenblatt Datenblatt

Empfohlene TUBA1A Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
  • (1)
Kat. Nr. ABIN7125523
Menge 50 μg
Datenblatt Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1324098
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1324100
Menge 10 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren TUBA1A Produkten

Chiu, Wen, Wang, Hsu, Tsai, Hung, Tseng, Shyr: "Role of estrogen receptors and Src signaling in mechanisms of bone metastasis by estrogen receptor positive breast cancers." in: Journal of translational medicine, Vol. 15, Issue 1, pp. 97, (2018) (PubMed).

Ambadipudi, Georges: "Sequences in Linker-1 domain of the multidrug resistance associated protein (MRP1 or ABCC1) bind to tubulin and their binding is modulated by phosphorylation." in: Biochemical and biophysical research communications, Vol. 482, Issue 4, pp. 1001-1006, (2017) (PubMed).

Schmid, Sailland, Novak, Baumlin, Fregien, Salathe: "Modulation of Wnt signaling is essential for the differentiation of ciliated epithelial cells in human airways." in: FEBS letters, Vol. 591, Issue 21, pp. 3493-3506, (2017) (PubMed).

Niemeyer, Kang, Shin, Furlan, Erlacher, Bunin, Bunda, Finklestein, Sakamoto, Gorr, Mehta, Schmid, Kropshofer, Corbacioglu, Lang, Klein, Schlegel, Heinzmann, Schneider, Starý, van den Heuvel-Eibrink et al.: "Germline CBL mutations cause developmental abnormalities and predispose to juvenile myelomonocytic leukemia. ..." in: Nature genetics, Vol. 42, Issue 9, pp. 794-800, (2010) (PubMed).

Fourest-Lieuvin, Peris, Gache, Garcia-Saez, Juillan-Binard, Lantez, Job: "Microtubule regulation in mitosis: tubulin phosphorylation by the cyclin-dependent kinase Cdk1." in: Molecular biology of the cell, Vol. 17, Issue 3, pp. 1041-50, (2006) (PubMed).

Westermann, Weber: "Post-translational modifications regulate microtubule function." in: Nature reviews. Molecular cell biology, Vol. 4, Issue 12, pp. 938-47, (2003) (PubMed).

Synonyme und alternative Namen zu TUBA1A

tubulin, alpha 1A (Tuba1a), tubulin alpha 1a (TUBA1A), tubulin, alpha 1a (TUBA1A), tubulin alpha-1B chain (LOC608147), tubulin alpha-1A chain (LOC100392817), tubulin alpha-3 chain-like (LOC425049), tubulin, alpha 1a (tuba1a), alpha-Tubulin at 84B (alphaTub84B), tubulin alpha-1A chain (LOC100051840), tubulin alpha-1A chain (LOC100340483), tubulin alpha-1A chain (LOC100726777), tubulin alpha 1a L homeolog (tuba1a.L), 1t, a-tub84B, a1t, alpha-Tub, alpha-tub, alpha-Tub84B, alpha-tub84B, alpha-tubulin, Alpha-Tubulin84B, alpha-tubulin 84B, alpha1, alpha1t, alpha1tub, alpha1tub84B, alpha84B, ALPHA 84C, alphaT, alphat-1, alphaTUB, alphaTub, alphatub, alphaTub1, alphaTub84, alphatub84, alphaTUB84B, alphatub84B, anon-EST:Liang-1.59, anon-EST:Liang-2.30, aTub84B, B-ALPHA-1, b-alpha-1, BEST:LD32507, CG1913, chr3R:2914276..2914416, clone 1.59, clone 2.30, DM1alpha, Dmel\CG1913, DTA1, l(3)84Bd, l(3)g3, LIS3, lis3, ms(3)nc33, nc33, T, Talpha1, TBA1_DROME, Tub, tub, Tub1C, Tub 84B, Tuba-1, Tuba1, TUBA1A, Tuba1a, tuba1a, tuba1a-a, tuba1a-b, Tuba2, TUBA3, tuba3, TUBA3D, TUBA3E, Tuba84B, tubA84B, Tubalpha1, tubalpha1, tubulin, wu:fb37a10

Bezeichner auf Proteinebene für TUBA1A

  • alpha-tubulin 1
  • tubulin alpha-1 chain
  • tubulin alpha-1A chain
  • tubulin, alpha 1
  • hum-a-tub1
  • hum-a-tub2
  • tubulin B-alpha-1
  • tubulin alpha-3 chain
  • tubulin, alpha, brain-specific
  • alpha-tubulin 3
  • tubulin, alpha 3
  • Talpha1 alpha-tubulin
  • alpha-tubulin isotype M-alpha-1
  • alpha-tubulin ubiquitous
  • tubulin K-alpha-1
  • tubulin alpha-1B chain
  • tubulin alpha-ubiquitous chain
  • tubulin, alpha 1a
  • tubulin alpha-1A chain-like
  • tubulin, alpha 3d
  • tubulin, alpha 3e
  • CG1913 gene product from transcript CG1913-RA
  • CG1913-PA
  • Tubulin-alpha1
  • alpha tubulin
  • alpha tubulin 84B
  • alpha-Tubulin
  • alpha-Tubulin 84B
  • alpha-tubulin84B
  • alpha1 tubulin
  • alpha1-tubulin
  • alphaT
  • alphaTub84B-PA
  • alphaTubulin 84B
  • alphaTubulin84B
  • alpha[[1]] tubulin
  • alpha[[1]]-tubulin
  • alphatubulin
  • tubulin
  • tubulin 1 alpha-chain
  • tubulin 1alpha
  • tubulin alpha1
  • tubulin alpha1 promoter
  • tubulin(alpha1)
  • tubulin1alpha
  • tubulin84B
  • Alpha-tubulin 1
  • Tubulin alpha-1 chain
  • tubulin alpha 3
  • Alpha-tubulin 2
  • Alpha-tubulin II
  • Tubulin alpha-2 chain
  • alpha-tubulin II
  • tubulin alpha 1a L homeolog
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