TYROBP Produkte
(TYRO Protein tyrosine Kinase Binding Protein (TYROBP))
Kategorien
This gene encodes a transmembrane signaling polypeptide which contains an immunoreceptor tyrosine-based activation motif (ITAM) in its cytoplasmic domain. The encoded protein may associate with the killer-cell inhibitory receptor (KIR) family of membrane glycoproteins and may act as an activating signal transduction element. This protein may bind zeta-chain (TCR) associated protein kinase 70kDa (ZAP-70) and spleen tyrosine kinase (SYK) and play a role in signal transduction, bone modeling, brain myelination, and inflammation. Mutations within this gene have been associated with polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy (PLOSL), also known as Nasu-Hakola disease. Its putative receptor, triggering receptor expressed on myeloid cells 2 (TREM2), also causes PLOSL. Multiple alternative transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Mar 2010].
antibodies-online.com steht für hochwertige Forschungsprodukte. Suchen, finden und bestellen Sie Tools mit umfangreichen Validierungsdaten, Bildern, Referenzen. Unser wissenschaftlicher Kundenservice steht Ihnen jederzeit zur Verfügung, wenn Sie Fragen zur Auswahl oder Anwendung unserer Produkte haben.
Ausgewählte TYROBP Kategorien
TYROBP Antikörper
High quality antibodies with extensive validation data.
TYROBP ELISA Kits
Reliable ELISA kits for a wide range of species.
TYROBP Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene TYROBP Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, FACS, IHC (p)
Validierungen
- (3)
Kat. Nr.
ABIN653819
Menge
400 μL
Datenblatt
Datenblatt
Reaktivität
Mouse, Rat
Applikation
IHC
Validierungen
- (2)
Kat. Nr.
ABIN7261337
Menge
200 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IHC, ELISA
Validierungen
- (2)
Kat. Nr.
ABIN6265826
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene TYROBP ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6971010
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6960320
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Mouse
Analytical Method
Quantitative Competition ELISA
Validierungen
Kat. Nr.
ABIN5593698
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene TYROBP Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1324265
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1324267
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
Kat. Nr.
ABIN7414999
Menge
100 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren TYROBP Produkten
: "Expansion and activation of distinct central memory T lymphocyte subsets in complex regional pain syndrome." in: Journal of neuroinflammation, Vol. 16, Issue 1, pp. 63, (2019) (PubMed).: "The female reproductive tract contains multiple innate sialic acid-binding immunoglobulin-like lectins (Siglecs) that facilitate sperm survival." in: The Journal of biological chemistry, Vol. 294, Issue 31, pp. 11910-11919, (2019) (PubMed).
: "CD33 modulates TREM2: convergence of Alzheimer loci." in: Nature neuroscience, Vol. 18, Issue 11, pp. 1556-8, (2016) (PubMed).
: "Th2-M2 immunity in lesions of muscular sarcoidosis and macrophagic myofasciitis." in: Neuropathology and applied neurobiology, Vol. 41, Issue 7, pp. 952-63, (2015) (PubMed).
: "DAP12 impacts trafficking and surface stability of killer immunoglobulin-like receptors on natural killer cells." in: Journal of leukocyte biology, Vol. 94, Issue 2, pp. 301-13, (2013) (PubMed).
: "The ITAM-bearing transmembrane adaptor DAP12 in lymphoid and myeloid cell function." in: Immunology today, Vol. 21, Issue 12, pp. 611-4, (2001) (PubMed).
: "Loss-of-function mutations in TYROBP (DAP12) result in a presenile dementia with bone cysts." in: Nature genetics, Vol. 25, Issue 3, pp. 357-61, (2000) (PubMed).
: "Combined natural killer cell and dendritic cell functional deficiency in KARAP/DAP12 loss-of-function mutant mice." in: Immunity, Vol. 13, Issue 3, pp. 355-64, (2000) (PubMed).
Synonyme und alternative Namen zu TYROBP
TYRO protein tyrosine kinase binding protein (TYROBP), TYRO protein tyrosine kinase binding protein (tyrobp), Tyro protein tyrosine kinase binding protein (Tyrobp), TYRO protein tyrosine kinase binding protein (Tyrobp), DAP12, dap12, Karap, KARAP, Ly83, PLOSL, TYROBP, tyrpbpBezeichner auf Proteinebene für TYROBP
- TYRO protein tyrosine kinase-binding protein
- TYRO protein tyrosine kinase binding protein
- DAP12 protein
- dap12
- DAP12
- DNAX-activation protein 12
- killer cell activating receptor-associated protein
- KAR-associated protein
- killer activating receptor associated protein
- killer-activating receptor-associated protein
- killer cell activating receptor associated protein
- immunoreceptor DAP12
- tyrosine kinase binding protein
Sie sind hier:
