UBA3 Produkte
(Ubiquitin-Like Modifier Activating Enzyme 3 (UBA3))
Kategorien
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E1 ubiquitin-activating enzyme family. The encoded enzyme associates with AppBp1, an amyloid beta precursor protein binding protein, to form a heterodimer, and then the enzyme complex activates NEDD8, a ubiquitin-like protein, which regulates cell division, signaling and embryogenesis. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
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Ausgewählte UBA3 Kategorien
UBA3 Antikörper
High quality antibodies with extensive validation data.
UBA3 ELISA Kits
Reliable ELISA kits for a wide range of species.
UBA3 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene UBA3 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human, Mouse
Applikation
WB, IHC (p)
Validierungen
- (4)
Kat. Nr.
ABIN387909
Menge
400 μL
Datenblatt
Datenblatt
Reaktivität
Human, Mouse, Rat
Applikation
WB, IHC, ELISA
Validierungen
- (2)
Kat. Nr.
ABIN6265835
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB
Validierungen
- (2)
Kat. Nr.
ABIN7271186
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene UBA3 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6971051
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Mouse
Analytical Method
Validierungen
Kat. Nr.
ABIN1144447
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Rat
Analytical Method
Validierungen
Kat. Nr.
ABIN1144448
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene UBA3 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1324294
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
- (1)
Kat. Nr.
ABIN7125641
Menge
50 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
Kat. Nr.
ABIN2132403
Menge
100 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren UBA3 Produkten
: "The covalent modifier Nedd8 is critical for the activation of Smurf1 ubiquitin ligase in tumorigenesis." in: Nature communications, Vol. 5, pp. 3733, (2014) (PubMed).: "Immunofluorescence and fluorescent-protein tagging show high correlation for protein localization in mammalian cells." in: Nature methods, Vol. 10, Issue 4, pp. 315-23, (2013) (PubMed).
: "Insights into the ubiquitin transfer cascade from the structure of the activating enzyme for NEDD8." in: Nature, Vol. 422, Issue 6929, pp. 330-4, (2003) (PubMed).
: "Conservation in the mechanism of Nedd8 activation by the human AppBp1-Uba3 heterodimer." in: The Journal of biological chemistry, Vol. 278, Issue 29, pp. 26823-30, (2003) (PubMed).
Synonyme und alternative Namen zu UBA3
ubiquitin like modifier activating enzyme 3 (UBA3), ubiquitin-like modifier activating enzyme 3 (Uba3), ubiquitin-like modifier activating enzyme 3 (uba3), ubiquitin like modifier activating enzyme 3 (uba3), ubiquitin like modifier activating enzyme 3 S homeolog (uba3.S), A830034N06Rik, AI256736, AI848246, AW546539, hUBA3, UBE1C, Ube1c, ube1c, wu:fb75e04, wu:fc37b11, zgc:55528Bezeichner auf Proteinebene für UBA3
- NEDD8-activating enzyme E1 catalytic subunit
- NEDD8-activating enzyme E1C
- Nedd8-activating enzyme hUba3
- UBA3, ubiquitin-activating enzyme E1 homolog
- ubiquitin-activating enzyme 3
- ubiquitin-activating enzyme E1C (UBA3 homolog, yeast)
- ubiquitin-activating enzyme E1C (homologous to yeast UBA3)
- ubiquitin-like modifier-activating enzyme 3
- ubiquitin activating enzyme 3
- ubiquitin-activating enzyme E1C
- ubiquitin-like modifier activating enzyme 3
- NEDD8-activating enzyme E1 catalytic subunit-like
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