ube3a Produkte
(Ubiquitin Protein Ligase E3A (ube3a))
Kategorien
This gene encodes an E3 ubiquitin-protein ligase, part of the ubiquitin protein degradation system. This imprinted gene is maternally expressed in brain and biallelically expressed in other tissues. Maternally inherited deletion of this gene causes Angelman Syndrome, characterized by severe motor and intellectual retardation, ataxia, hypotonia, epilepsy, absence of speech, and characteristic facies. The protein also interacts with the E6 protein of human papillomavirus types 16 and 18, resulting in ubiquitination and proteolysis of tumor protein p53. Alternative splicing of this gene results in three transcript variants encoding three isoforms with different N-termini. Additional transcript variants have been described, but their full length nature has not been determined. [provided by RefSeq, Jul 2008].
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Ausgewählte ube3a Kategorien
ube3a Antikörper
High quality antibodies with extensive validation data.
ube3a ELISA Kits
Reliable ELISA kits for a wide range of species.
ube3a Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene ube3a Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IF, IHC (p)
Validierungen
- (1)
- (6)
Kat. Nr.
ABIN563326
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human, Mouse, Rat
Applikation
IHC, IF
Validierungen
- (11)
Kat. Nr.
ABIN7076105
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IF, IHC (p), FACS
Validierungen
- (1)
- (4)
Kat. Nr.
ABIN388925
Menge
400 μL
Datenblatt
Datenblatt
Empfohlene ube3a ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6971042
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6960350
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN1572964
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene ube3a Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1324426
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1324424
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
Kat. Nr.
ABIN7393133
Menge
100 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren ube3a Produkten
: "Cognition and Synaptic-Plasticity Related Changes in Aged Rats Supplemented with 8- and 10-Carbon Medium Chain Triglycerides." in: PLoS ONE, Vol. 11, Issue 8, pp. e0160159, (2017) (PubMed).: "A coding-independent function of an alternative Ube3a transcript during neuronal development." in: Nature neuroscience, Vol. 18, Issue 5, pp. 666-73, (2015) (PubMed).
: "A fine balance: Regulation of hippocampal Arc/Arg3.1 transcription, translation and degradation in a rat model of normal cognitive aging." in: Neurobiology of learning and memory, Vol. 115, pp. 58-67, (2014) (PubMed).
: "Interaction of HPV E6 oncoproteins with specific proteasomal subunits." in: Virology, Vol. 446, Issue 1-2, pp. 389-96, (2013) (PubMed).
: "E6AP ubiquitin ligase regulates PML-induced senescence in Myc-driven lymphomagenesis." in: Blood, Vol. 120, Issue 4, pp. 822-32, (2012) (PubMed).
: "Ube3a-ATS is an atypical RNA polymerase II transcript that represses the paternal expression of Ube3a." in: Human molecular genetics, Vol. 21, Issue 13, pp. 3001-12, (2012) (PubMed).
: "Spatial and temporal silencing of the human maternal UBE3A gene." in: European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society, Vol. 16, Issue 6, pp. 587-91, (2012) (PubMed).
: "Adeno-associated virus-mediated rescue of the cognitive defects in a mouse model for Angelman syndrome." in: PLoS ONE, Vol. 6, Issue 12, pp. e27221, (2011) (PubMed).
: "Genomic imprinting of experience-dependent cortical plasticity by the ubiquitin ligase gene Ube3a." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 107, Issue 12, pp. 5611-6, (2010) (PubMed).
: "Isoform-specific degradation of PR-B by E6-AP is critical for normal mammary gland development." in: Molecular endocrinology (Baltimore, Md.), Vol. 24, Issue 11, pp. 2099-113, (2010) (PubMed).
Synonyme und alternative Namen zu ube3a
ubiquitin protein ligase E3A (UBE3A), ubiquitin-protein ligase E3A (ube3a), ubiquitin-protein ligase E3A (LOC100194730), ubiquitin protein ligase E3A (Ube3a), ubiquitin protein ligase E3A (ube3a), Ubiquitin protein ligase E3A (Ube3a), ubiquitin protein ligase E3A (human papilloma virus E6-associated protein, Angelman syndrome) S homeolog (ube3a.S), ubiquitin protein ligase E3A (human papilloma virus E6-associated protein, Angelman syndrome) (ube3a), ubiquitin protein ligase E3A (Eint_040430), 4732496B02, 5830462N02Rik, A130086L21Rik, ANCR, AS, As, CG6190, das, DDBDRAFT_0188760, DDBDRAFT_0302447, DDB_0188760, DDB_0302447, Dmel\\CG6190, Dube3a, dUBE3A, dube3A, dube3a, E6-AP, EPVE6AP, HPVE6A, Hpve6a, im:7140733, MGC69536, mKIAA4216, ube3a, UBE3A, UME3A, zgc:92173Bezeichner auf Proteinebene für ube3a
- CTCL tumor antigen se37-2
- E6AP ubiquitin-protein ligase
- human papilloma virus E6-associated protein
- human papillomavirus E6-associated protein
- oncogenic protein-associated protein E6-AP
- renal carcinoma antigen NY-REN-54
- ubiquitin-protein ligase E3A
- ubiquitin protein ligase E3A (human papilloma virus E6-associated protein, Angelman syndrome)
- ubiquitin protein ligase E3A
- E6-AP ubiquitin protein ligase
- ubiquitin conjugating enzyme E3A
- CG6190-PA
- Ube3a-PA
- drosophila angelman syndrome
- angelman syndrome
- ubiquitin-protein ligase E3A-like
Haben Sie etwas anderes gesucht?
- UBE2Z
- UBE2W
- UBE2V2
- UBE2V1
- UBE2U
- Ube2t
- UBE2S.2
- UBE2R2
- UBE2QL1
- UBE2Q2
- UBE2Q1
- UBE2O
- UBE2NL
- UBE2M
- UBE2L6
- UBE2L3
- UBE2J2
- UBE2J1
- UBE2I2
- UBE2H
- UBE3B
- UBE3C
- UBE3D
- UBE4A
- UBE4B
- UBFD1
- UBIAD1
- UBIM
- Ubinuclein 1
- Ubiquilin 1
- Ubiquilin 2
- Ubiquilin 3
- Ubiquinol-Cytochrome C Reductase Complex Assembly Factor 3
- Ubiquinol-Cytochrome C Reductase Complex Chaperone
- Ubiquinol-Cytochrome C Reductase Core Protein II
- Ubiquitin
- Ubiquitin +1
- Ubiquitin 11
- Ubiquitin Associated Protein 1
- Ubiquitin B
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