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Ubiquilin 1 Produkte

(Ubiquilin 1 (UBQLN1))
This gene encodes an ubiquitin-like protein (ubiquilin) that shares a high degree of similarity with related products in yeast, rat and frog. Ubiquilins contain an N-terminal ubiquitin-like domain and a C-terminal ubiquitin-associated domain. They physically associate with both proteasomes and ubiquitin ligases, and thus are thought to functionally link the ubiquitination machinery to the proteasome to affect in vivo protein degradation. This ubiquilin has also been shown to modulate accumulation of presenilin proteins, and it is found in lesions associated with Alzheimer's and Parkinson's disease. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].

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Ausgewählte Ubiquilin 1 Kategorien

Ubiquilin 1 Antikörper

High quality antibodies with extensive validation data.

Ubiquilin 1 ELISA Kits

Reliable ELISA kits for a wide range of species.

Ubiquilin 1 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene Ubiquilin 1 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human, Mouse
Applikation WB, IHC (p), IF
Validierungen
  • (3)
  • (3)
Kat. Nr. ABIN388966
Menge 400 μL
Datenblatt Datenblatt
Reaktivität Cow, Dog, Guinea Pig, Horse, Human, Monkey, Rabbit, Sheep
Applikation WB, IHC, IHC (p)
Validierungen
  • (4)
Kat. Nr. ABIN6741620
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human, Mouse
Applikation WB, ELISA, IHC, IF
Validierungen
  • (5)
Kat. Nr. ABIN3029415
Menge 0.4 mL
Datenblatt Datenblatt

Empfohlene Ubiquilin 1 ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6971031
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Rat
Analytical Method Quantitative Sandwich ELISA
Validierungen
Kat. Nr. ABIN6208313
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Mouse
Analytical Method
Validierungen
Kat. Nr. ABIN1164827
Menge 96 tests
Datenblatt Datenblatt

Empfohlene Ubiquilin 1 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1324458
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source HEK-293 Cells
Validierungen
  • (1)
Kat. Nr. ABIN2734885
Menge 20 μg
Datenblatt Datenblatt
Reaktivität Human
Source HEK-293 Cells
Validierungen
  • (1)
Kat. Nr. ABIN2734886
Menge 20 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren Ubiquilin 1 Produkten

Chen, Wang, Jiang, Zheng, Justice, Wang, Ran, Li, Huo, Zhang, Li, Lu, Wang, Zheng, Long, Yang: "APP modulates KCC2 expression and function in hippocampal GABAergic inhibition." in: eLife, Vol. 6, (2018) (PubMed).

Sun, Liu, Yuan, Guo, Xie, Du, Lin, Xu, Liu, Wang, Yuan, Chen: "MiR-200c inhibits autophagy and enhances radiosensitivity in breast cancer cells by targeting UBQLN1." in: International journal of cancer. Journal international du cancer, Vol. 136, Issue 5, pp. 1003-12, (2014) (PubMed).

Bieniek, Murray, Rutherford, Castanedes-Casey, DeJesus-Hernandez, Liesinger, Baker, Boylan, Rademakers, Dickson: "Tau pathology in frontotemporal lobar degeneration with C9ORF72 hexanucleotide repeat expansion." in: Acta neuropathologica, Vol. 125, Issue 2, pp. 289-302, (2013) (PubMed).

Bao, Zhang, Zheng, Xu, Yan: "UBQLN1 interacts with SPEM1 and participates in spermiogenesis." in: Molecular and cellular endocrinology, Vol. 327, Issue 1-2, pp. 89-97, (2010) (PubMed).

Sick, Boukhari, Deramaudt, Rondé, Bucher, André, Gies, Takeda: "Activation of CD47 receptors causes proliferation of human astrocytoma but not normal astrocytes via an Akt-dependent pathway." in: Glia, Vol. 59, Issue 2, pp. 308-19, (2010) (PubMed).

Massey, Mah, Ford, Miller, Liang, Doong, Monteiro: "Overexpression of ubiquilin decreases ubiquitination and degradation of presenilin proteins." in: Journal of Alzheimer's disease : JAD, Vol. 6, Issue 1, pp. 79-92, (2004) (PubMed).

Gao, Tu, Shi, Lee, Asanaka, Hwang, Lai: "Interaction with a ubiquitin-like protein enhances the ubiquitination and degradation of hepatitis C virus RNA-dependent RNA polymerase." in: Journal of virology, Vol. 77, Issue 7, pp. 4149-59, (2003) (PubMed).

Kleijnen, Shih, Zhou, Kumar, Soccio, Kedersha, Gill, Howley: "The hPLIC proteins may provide a link between the ubiquitination machinery and the proteasome." in: Molecular cell, Vol. 6, Issue 2, pp. 409-19, (2000) (PubMed).

Mah, Perry, Smith, Monteiro: "Identification of ubiquilin, a novel presenilin interactor that increases presenilin protein accumulation." in: The Journal of cell biology, Vol. 151, Issue 4, pp. 847-62, (2000) (PubMed).

Synonyme und alternative Namen zu Ubiquilin 1

ubiquilin 1 (UBQLN1), ubiquilin 1 (Ubqln1), 1110046H03Rik, 1810030E05Rik, AU019746, C77538, D13Ertd372e, DA41, Da41, DSK2, Dsk2, PLIC-1, Plic-1, Plic1, UBQLN1, UBQN, XDRP1, Xdrp1

Bezeichner auf Proteinebene für Ubiquilin 1

  • ubiquilin-1
  • ubiquilin 1
  • ubiquilin-1-like
  • hPLIC-1
  • protein linking IAP with cytoskeleton 1
  • PLIC-1
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