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Ubiquitin B Produkte

(Ubiquitin B (UBB))
This gene encodes ubiquitin, one of the most conserved proteins known. Ubiquitin is required for ATP-dependent, nonlysosomal intracellular protein degradation of abnormal proteins and normal proteins with a rapid turnover. Ubiquitin is covalently bound to proteins to be degraded, and presumably labels these proteins for degradation. Ubiquitin also binds to histone H2A in actively transcribed regions but does not cause histone H2A degradation, suggesting that ubiquitin is also involved in regulation of gene expression. This gene consists of three direct repeats of the ubiquitin coding sequence with no spacer sequence. Consequently, the protein is expressed as a polyubiquitin precursor with a final amino acid after the last repeat. Aberrant form of this protein has been noticed in patients with Alzheimer's and Down syndrome. [provided by RefSeq, Jul 2008].

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Ausgewählte Ubiquitin B Kategorien

Ubiquitin B Antikörper

High quality antibodies with extensive validation data.

Ubiquitin B ELISA Kits

Reliable ELISA kits for a wide range of species.

Ubiquitin B Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene Ubiquitin B Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB, IHC, FACS, IF, StM
Validierungen
  • (6)
Kat. Nr. ABIN6940844
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, ELISA, FACS
Validierungen
  • (2)
  • (4)
Kat. Nr. ABIN969573
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, IHC, ELISA, StM, Coat
Validierungen
  • (5)
Kat. Nr. ABIN6940845
Menge 100 μg
Datenblatt Datenblatt

Empfohlene Ubiquitin B ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6971035
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Rat
Analytical Method
Validierungen
  • (1)
Kat. Nr. ABIN579427
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Mouse
Analytical Method
Validierungen
Kat. Nr. ABIN456733
Menge 96 tests
Datenblatt Datenblatt

Empfohlene Ubiquitin B Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1324322
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
Kat. Nr. ABIN2115459
Menge 50 μg
Datenblatt Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
Kat. Nr. ABIN7318921
Menge 50 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren Ubiquitin B Produkten

Yang, Liu, Yao, Jiang, Wang, Yang, Sun, Miao, Wang, Huang, Wang, Tang, Rayner, Britt, McVoy, Luo, Zhao: "WDR5 Facilitates Human Cytomegalovirus Replication by Promoting Capsid Nuclear Egress." in: Journal of virology, Vol. 92, Issue 9, (2018) (PubMed).

Zhang, Wang, Zhong, Luo, Shang, Liu, Chen, Fang, Xiao: "Ubiquitin-specific Protease 15 Negatively Regulates Virus-induced Type I Interferon Signaling via Catalytically-dependent and -independent Mechanisms." in: Scientific reports, Vol. 5, pp. 11220, (2016) (PubMed).

Cheng, Wang, Jiang, Wang, Xin, Liu, Jia, Song, Zhu: "A novel ubiquitin-protein ligase E3 functions as a modulator of immune response against lipopolysaccharide in Pacific oyster, Crassostrea gigas." in: Developmental and comparative immunology, Vol. 60, pp. 180-90, (2016) (PubMed).

Li, Liu, Yang, Fu, Zhao, Shen, Miao, Rayner, Chavanas, Zhu, Britt, Tang, McVoy, Luo: "Human Cytomegalovirus Infection Dysregulates the Localization and Stability of NICD1 and Jag1 in Neural Progenitor Cells." in: Journal of virology, Vol. 89, Issue 13, pp. 6792-804, (2015) (PubMed).

Zhong, Wang, Fang, Zhang, Luo, Shang, Ouyang, Ouyang, Chen, Xiao: "Ubiquitin-specific proteases 25 negatively regulates virus-induced type I interferon signaling." in: PLoS ONE, Vol. 8, Issue 11, pp. e80976, (2013) (PubMed).

Di Filippo, Capuano, Rinaldi, Luongo, Lettieri, Rossi, DAmico: "Intraperitoneal oxygen/ozone treatment decreases the formation of experimental postsurgical peritoneal adhesions and the levels/activity of the local ubiquitin-proteasome system." in: Mediators of inflammation, Vol. 2011, pp. 606718, (2012) (PubMed).

Choudhary, Kumar, Gnad, Nielsen, Rehman, Walther, Olsen, Mann: "Lysine acetylation targets protein complexes and co-regulates major cellular functions." in: Science (New York, N.Y.), Vol. 325, Issue 5942, pp. 834-40, (2009) (PubMed).

Komander: "The emerging complexity of protein ubiquitination." in: Biochemical Society transactions, Vol. 37, Issue Pt 5, pp. 937-53, (2009) (PubMed).

Vernes, Nicod, Elahi, Coventry, Kenny, Coupe, Bird, Davies, Fisher: "Functional genetic analysis of mutations implicated in a human speech and language disorder." in: Human molecular genetics, Vol. 15, Issue 21, pp. 3154-67, (2006) (PubMed).

Synonyme und alternative Namen zu Ubiquitin B

ubiquitin B (UBB), ubiquitin B (Ubb), ubiquitin C (UBC), ubiquitin B (ubb), AL033289, im:6892314, Rps27a, si:ch211-202a12.3, Uba52, UBB, Ubb2, Ubc, UBC, ubc, Ubi-p63E, Ubiquitin, zgc:172187, zUBC

Bezeichner auf Proteinebene für Ubiquitin B

  • polyubiquitin B
  • polyubiquitin-B
  • polyubiquitin
  • ubiquitin C
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