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UHMK1 Produkte

(U2AF Homology Motif (UHM) Kinase 1 (UHMK1))

Kategorien

The gene encodes a serine/threonine protein kinase that promotes cell cycle progression through G1 by phosphorylation of the cyclin-dependent kinase inhibitor 1B (p27Kip1), which causes nuclear export and degradation. The encoded protein is also thought to function in the adult nervous system and the gene has been associated with schizophrenia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2010].

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Ausgewählte UHMK1 Kategorien

UHMK1 Antikörper

High quality antibodies with extensive validation data.

UHMK1 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene UHMK1 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human, Mouse
Applikation WB, IHC (p)
Validierungen
  • (6)
  • (3)
Kat. Nr. ABIN392641
Menge 400 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, ELISA, IHC, IF
Validierungen
  • (3)
Kat. Nr. ABIN7169055
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human, Mouse
Applikation WB
Validierungen
  • (2)
Kat. Nr. ABIN6243411
Menge 400 μL
Datenblatt Datenblatt

Empfohlene UHMK1 ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
Kat. Nr. ABIN6225152
Menge 96 tests
Datenblatt Datenblatt

Empfohlene UHMK1 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
  • (1)
Kat. Nr. ABIN1324602
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1324604
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Tobacco (Nicotiana tabacum)
Validierungen
Kat. Nr. ABIN3075295
Menge 1 mg
Datenblatt Datenblatt

Neueste Publikationen zu unseren UHMK1 Produkten

Chen, Xie, Gu, Cai, Wang, Xie, Dong, He, Zhong, Lin, Huang: "Upregulated WDR5 promotes proliferation, self-renewal and chemoresistance in bladder cancer via mediating H3K4 trimethylation." in: Scientific reports, Vol. 5, pp. 8293, (2015) (PubMed).

Lee, Kay: "PI 3-kinase/Rac1 and ERK1/2 regulate FGF-2-mediated cell proliferation through phosphorylation of p27 at Ser10 by KIS and at Thr187 by Cdc25A/Cdk2." in: Investigative ophthalmology & visual science, Vol. 52, Issue 1, pp. 417-26, (2011) (PubMed).

Nakamura, Yamashita, Yokota, Hirano, Ono, Fujie, Shibata, Niimi, Suyama, Maddali, Asai, Yamashita, Iguchi, Ohnishi: "Development and pharmacologic characterization of deoxybromophospha sugar derivatives with antileukemic activity." in: Investigational new drugs, Vol. 28, Issue 4, pp. 381-91, (2010) (PubMed).

Takemura, Nakamura, Yokota, Hirano, Ono, Shigeno, Fujisawa, Ohnishi: "Reduction of Raf kinase inhibitor protein expression by Bcr-Abl contributes to chronic myelogenous leukemia proliferation." in: The Journal of biological chemistry, Vol. 285, Issue 9, pp. 6585-94, (2010) (PubMed).

Nakamura, Hirano, Okinaka, Takemura, Yokota, Ono, Shigeno, Shibata, Fujisawa, Ohnishi: "The FOXM1 transcriptional factor promotes the proliferation of leukemia cells through modulation of cell cycle progression in acute myeloid leukemia." in: Carcinogenesis, Vol. 31, Issue 11, pp. 2012-21, (2010) (PubMed).

Bristow, Lane, Walker, Chen, Sei, Hyde, Kleinman, Harrison, Eastwood: "Expression of kinase interacting with stathmin (KIS, UHMK1) in human brain and lymphoblasts: Effects of schizophrenia and genotype." in: Brain research, Vol. 1301, pp. 197-206, (2009) (PubMed).

Nakamura, Okinaka, Hirano, Ono, Sugimoto, Shigeno, Fujisawa, Shinjo, Ohnishi: "KIS induces proliferation and the cell cycle progression through the phosphorylation of p27Kip1 in leukemia cells." in: Leukemia research, Vol. 32, Issue 9, pp. 1358-65, (2008) (PubMed).

Petrovic, Costa, Lau, Raychaudhuri, Tyner: "FoxM1 regulates growth factor-induced expression of kinase-interacting stathmin (KIS) to promote cell cycle progression." in: The Journal of biological chemistry, Vol. 283, Issue 1, pp. 453-60, (2007) (PubMed).

Bièche, Manceau, Curmi, Laurendeau, Lachkar, Leroy, Vidaud, Sobel, Maucuer: "Quantitative RT-PCR reveals a ubiquitous but preferentially neural expression of the KIS gene in rat and human." in: Brain research. Molecular brain research, Vol. 114, Issue 1, pp. 55-64, (2003) (PubMed).

Boehm, Yoshimoto, Crook, Nallamshetty, True, Nabel, Nabel: "A growth factor-dependent nuclear kinase phosphorylates p27(Kip1) and regulates cell cycle progression." in: The EMBO journal, Vol. 21, Issue 13, pp. 3390-401, (2002) (PubMed).

Synonyme und alternative Namen zu UHMK1

U2AF homology motif kinase 1 (UHMK1), U2AF homology motif (UHM) kinase 1 (uhmk1), U2AF homology motif (UHM) kinase 1 (UHMK1), U2AF homology motif (UHM) kinase 1 (Uhmk1), U2AF homology motif kinase 1 (Uhmk1), 4732477C12Rik, 4930500M09Rik, AA673513, AI449218, AU021979, KIS, KIST, Kist, P-CIP2, UHMK1, zgc:153241

Bezeichner auf Proteinebene für UHMK1

  • U2AF homology motif (UHM) kinase 1
  • kinase interacting stathmin
  • serine/threonine-protein kinase Kist
  • serine/threonine-protein kinase Kist-like
  • KIS protein kinase
  • PAM COOH-terminal interactor protein 2
  • kinase interacting with leukemia-associated gene (stathmin)
  • U2AF homology motif kinase 1
  • kinase interacting with stathmin
  • P-CIP2
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