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UMPS Produkte

(Uridine Monophosphate Synthetase (UMPS))

Kategorien

This gene encodes a uridine 5'-monophosphate synthase. The encoded protein is a bifunctional enzyme that catalyzes the final two steps of the de novo pyrimidine biosynthetic pathway. The first reaction is carried out by the N-terminal enzyme orotate phosphoribosyltransferase which converts orotic acid to orotidine-5'-monophosphate. The terminal reaction is carried out by the C-terminal enzyme OMP decarboxylase which converts orotidine-5'-monophosphate to uridine monophosphate. Defects in this gene are the cause of hereditary orotic aciduria. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Mar 2010].

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Ausgewählte UMPS Kategorien

UMPS Antikörper

High quality antibodies with extensive validation data.

UMPS Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene UMPS Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt

Applikation WB, IHC
Validierungen
  • (1)
  • (6)
Kat. Nr. ABIN2783243
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, ELISA, IF
Validierungen
  • (1)
  • (4)
Kat. Nr. ABIN521259
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Applikation ELISA, IHC, IF
Validierungen
  • (3)
Kat. Nr. ABIN7175108
Menge 100 μg
Datenblatt Datenblatt

Empfohlene UMPS Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1324639
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1324637
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source HEK-293 Cells
Validierungen
  • (1)
  • (1)
Kat. Nr. ABIN2735007
Menge 20 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren UMPS Produkten

Griffith, Mwenifumbo, Cheung, Paul, Pugh, Tang, Chittaranjan, Morin, Asano, Ally, Miao, Lee, Chan, Taylor, Severson, Hou, Griffith, Cheng, Novik, Moore, Luk, Owen, Brown, Morin, Gill, Tai, Marra: "Novel mRNA isoforms and mutations of uridine monophosphate synthetase and 5-fluorouracil resistance in colorectal cancer." in: The pharmacogenomics journal, Vol. 13, Issue 2, pp. 148-58, (2013) (PubMed).

Bardeleben, Sharma, Reeve, Bassilian, Frost, Hoang, Shi, Lichtenstein: "Metabolomics identifies pyrimidine starvation as the mechanism of 5-aminoimidazole-4-carboxamide-1-β-riboside-induced apoptosis in multiple myeloma cells." in: Molecular cancer therapeutics, Vol. 12, Issue 7, pp. 1310-21, (2013) (PubMed).

Koopman, Venderbosch, van Tinteren, Ligtenberg, Nagtegaal, Van Krieken, Punt: "Predictive and prognostic markers for the outcome of chemotherapy in advanced colorectal cancer, a retrospective analysis of the phase III randomised CAIRO study." in: European journal of cancer (Oxford, England : 1990), Vol. 45, Issue 11, pp. 1999-2006, (2009) (PubMed).

Ishikawa, Kondo, Yamaguchi, Sakamoto, Fujisawa: "Effect of varicocelectomy on patients with unobstructive azoospermia and severe oligospermia." in: BJU international, Vol. 101, Issue 2, pp. 216-8, (2008) (PubMed).

Synonyme und alternative Namen zu UMPS

Orotidine 5'-phosphate decarboxylase (umps-1), uridine monophosphate synthetase (umps), uridine monophosphate synthetase L homeolog (umps.L), uridine monophosphate synthetase (UMPS), uridine 5'-monophosphate synthase (LOC100556619), uridine monophosphate synthetase (Umps), 1700095D23Rik, AA408257, AL033308, BB164745, OPRT, UMPS, zgc:55702, zgc:55723

Bezeichner auf Proteinebene für UMPS

  • Uridine MonoPhosphate Synthetase family member (umps-1)
  • uridine 5'-monophosphate synthase
  • uridine monophosphate synthetase
  • uridine monophosphate synthase
  • uridine monophosphate synthetase (orotate phosphoribosyl transferase and orotidine-5'-decarboxylase)
  • OMPdecase
  • OPRTase
  • UMP synthase
  • orotate phosphoribosyltransferase
  • orotidine 5'-phosphate decarboxylase
  • orotate phosphoribosyl transferase and orotidine-5'-decarboxylase
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