UNC13B Produkte
(Unc-13 Homolog B (UNC13B))
Kategorien
This gene is expressed in the kidney cortical epithelial cells and is upregulated by hyperglycemia. The encoded protein shares a high level of similarity to the rat homolog, and contains 3 C2 domains and a diacylglycerol-binding C1 domain. Hyperglycemia increases the levels of diacylglycerol, which has been shown to induce apoptosis in cells transfected with this gene and thus contribute to the renal cell complications of hyperglycemia. Studies in other species also indicate a role for this protein in the priming step of synaptic vesicle exocytosis. [provided by RefSeq, Jul 2008].
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Ausgewählte UNC13B Kategorien
UNC13B Antikörper
High quality antibodies with extensive validation data.
Empfohlene UNC13B Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IHC, IF
Validierungen
- (3)
Kat. Nr.
ABIN7166241
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, FACS
Validierungen
- (1)
- (2)
Kat. Nr.
ABIN652852
Menge
400 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IF, IHC (p), ICC
Validierungen
- (3)
Kat. Nr.
ABIN2856793
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene UNC13B Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1324644
Menge
10 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren UNC13B Produkten
: "CAPS and Munc13 utilize distinct PIP2-linked mechanisms to promote vesicle exocytosis." in: Molecular biology of the cell, Vol. 25, Issue 4, pp. 508-21, (2014) (PubMed).: "Size-dependent mechanism of cargo sorting during lysosome-phagosome fusion is controlled by Rab34." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 109, Issue 50, pp. 20485-90, (2012) (PubMed).
: "Early steps in the assembly of photoreceptor ribbon synapses in the mouse retina: the involvement of precursor spheres." in: The Journal of comparative neurology, Vol. 512, Issue 6, pp. 814-24, (2008) (PubMed).
: "Detection of novel amplicons in prostate cancer by comprehensive genomic profiling of prostate cancer cell lines using oligonucleotide-based arrayCGH." in: PLoS ONE, Vol. 2, Issue 8, pp. e769, (2007) (PubMed).
: "Munc13-1 is a presynaptic phorbol ester receptor that enhances neurotransmitter release." in: Neuron, Vol. 21, Issue 1, pp. 123-36, (1998) (PubMed).
: "A novel brain-specific isoform of beta spectrin: isolation and its interaction with Munc13." in: Biochemical and biophysical research communications, Vol. 248, Issue 3, pp. 846-51, (1998) (PubMed).
: "Physical and functional interactions of Doc2 and Munc13 in Ca2+-dependent exocytotic machinery." in: The Journal of biological chemistry, Vol. 272, Issue 26, pp. 16081-4, (1997) (PubMed).
: "Mammalian homologues of Caenorhabditis elegans unc-13 gene define novel family of C2-domain proteins." in: The Journal of biological chemistry, Vol. 270, Issue 42, pp. 25273-80, (1995) (PubMed).
Synonyme und alternative Namen zu UNC13B
unc-13 homolog B (UNC13B), unc-13 homolog B (Unc13b), unc-13 homolog B (C. elegans) (Unc13b), MUNC13, Munc13-1, Munc13-2, UNC13, Unc13a, UNC13B, Unc13h1, Unc13h2Bezeichner auf Proteinebene für UNC13B
- homolog of rat Munc13 (diacylglycerol-binding)
- munc13-2
- protein unc-13 homolog B
- unc-13 homolog B (C. elegans)
- unc-13 B-like protein
- UNC-13 homolog 1
- munc13
- unc-13 homolog A
- unc13 homolog 1
- protein unc-13 homolog B-like
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