Uromodulin Produkte
(Uromodulin (UMOD))
Kategorien
This gene encodes uromodulin, the most abundant protein in normal urine. Its excretion in urine follows proteolytic cleavage of the ectodomain of its glycosyl phosphatidylinosital-anchored counterpart that is situated on the luminal cell surface of the loop of Henle. Uromodulin may act as a constitutive inhibitor of calcium crystallization in renal fluids. Excretion of uromodulin in urine may provide defense against urinary tract infections caused by uropathogenic bacteria. Defects in this gene are associated with the autosomal dominant renal disorders medullary cystic kidney disease-2 (MCKD2) and familial juvenile hyperuricemic nephropathy (FJHN). These disorders are characterized by juvenile onset of hyperuricemia, gout, and progressive renal failure. While several transcript variants may exist for this gene, the full-length natures of only two have been described to date. These two represent the major variants of this gene and encode the same isoform. [provided by RefSeq, Jul 2008].
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Ausgewählte Uromodulin Kategorien
Uromodulin Antikörper
High quality antibodies with extensive validation data.
Uromodulin ELISA Kits
Reliable ELISA kits for a wide range of species.
Uromodulin Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene Uromodulin Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human, Mouse, Rat
Applikation
WB, ELISA, IHC (p), IHC (fro), FACS, IF (p), IF (cc)
Validierungen
- (2)
- (4)
Kat. Nr.
ABIN678473
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IP
Validierungen
- (2)
- (4)
Kat. Nr.
ABIN521253
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Dog
Applikation
WB, IHC, IP, ICC
Validierungen
- (4)
Kat. Nr.
ABIN7437641
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene Uromodulin ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
- (1)
Kat. Nr.
ABIN6960396
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Rat
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (2)
- (1)
Kat. Nr.
ABIN6960397
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6971085
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene Uromodulin Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1324635
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1324633
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
Kat. Nr.
ABIN7505005
Menge
100 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren Uromodulin Produkten
: "The effect of O-1602, a GPR55 agonist, on the cyclophosphamide-induced rat hemorrhagic cystitis." in: European journal of pharmacology, Vol. 882, pp. 173321, (2020) (PubMed).: "Impaired mitophagy links mitochondrial disease to epithelial stress in methylmalonyl-CoA mutase deficiency." in: Nature communications, Vol. 11, Issue 1, pp. 970, (2020) (PubMed).
: "Fate of Neutrophils during the Recovery Phase of Ischemia/Reperfusion Induced Acute Kidney Injury." in: Journal of Korean medical science, Vol. 32, Issue 10, pp. 1616-1625, (2018) (PubMed).
: "Blocking junctional adhesion molecule C promotes the recovery of cisplatin-induced acute kidney injury." in: The Korean journal of internal medicine, Vol. 32, Issue 6, pp. 1053-1061, (2018) (PubMed).
: "The serine protease hepsin mediates urinary secretion and polymerisation of Zona Pellucida domain protein uromodulin." in: eLife, Vol. 4, pp. e08887, (2016) (PubMed).
: "Urinary biomarkers of chronic allograft nephropathy." in: Proteomics. Clinical applications, Vol. 9, Issue 5-6, pp. 574-85, (2015) (PubMed).
: "Urine uromodulin estimation in partial bladder outlet obstruction and cyclophosphamide-induced haemorrhagic cystitis models in rats." in: Postȩpy higieny i medycyny doświadczalnej (Online), Vol. 68, pp. 1184-92, (2015) (PubMed).
: "Glucose-induced down regulation of thiamine transporters in the kidney proximal tubular epithelium produces thiamine insufficiency in diabetes." in: PLoS ONE, Vol. 7, Issue 12, pp. e53175, (2013) (PubMed).
: "Mass spectrometric study of stone matrix proteins of human bladder stones." in: Urology, Vol. 82, Issue 2, pp. 295-300, (2013) (PubMed).
: "Proteomic study of renal uric acid stone." in: Urology, Vol. 80, Issue 2, pp. 260-6, (2012) (PubMed).
Synonyme und alternative Namen zu Uromodulin
uromodulin (UMOD), uromodulin (Umod), ADMCKD2, FJHN, HNFJ, HNFJ1, MCKD2, THGP, THP, urehr4Bezeichner auf Proteinebene für Uromodulin
- uromodulin
- Tamm-Horsfall urinary glycoprotein
- uromucoid
- THP
- tamm-Horsfall urinary glycoprotein
- uromodulin (uromucoid, Tamm-Horsfall glycoprotein)
- Urmodulin (Tamm-Horsfall protein)
- uromucoid, human : Tamm-Horsfall glycoprotein
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