USP14 Produkte
(Ubiquitin Specific Peptidase 14 (USP14))
Kategorien
This gene encodes a member of the ubiquitin-specific processing (UBP) family of proteases that is a deubiquitinating enzyme (DUB) with His and Cys domains. This protein is located in the cytoplasm and cleaves the ubiquitin moiety from ubiquitin-fused precursors and ubiquitinylated proteins. Mice with a mutation that results in reduced expression of the ortholog of this protein are retarded for growth, develop severe tremors by 2 to 3 weeks of age followed by hindlimb paralysis and death by 6 to 10 weeks of age. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008].
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Ausgewählte USP14 Kategorien
USP14 Antikörper
High quality antibodies with extensive validation data.
USP14 ELISA Kits
Reliable ELISA kits for a wide range of species.
USP14 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene USP14 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IF
Validierungen
- (1)
- (8)
Kat. Nr.
ABIN563939
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IHC (p)
Validierungen
- (1)
- (4)
Kat. Nr.
ABIN388902
Menge
400 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA
Validierungen
- (5)
Kat. Nr.
ABIN563938
Menge
50 μL
Datenblatt
Datenblatt
Empfohlene USP14 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6960351
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
Kat. Nr.
ABIN5659744
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene USP14 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1324754
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1324752
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
- (1)
Kat. Nr.
ABIN2132479
Menge
100 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren USP14 Produkten
: "Ubiquitin-specific protease-14 reduces cellular aggregates and protects against mutant huntingtin-induced cell degeneration: involvement of the proteasome and ER stress-activated kinase IRE1?." in: Human molecular genetics, Vol. 23, Issue 22, pp. 5928-39, (2014) (PubMed).: "New genetic associations detected in a host response study to hepatitis B vaccine." in: Genes and immunity, Vol. 11, Issue 3, pp. 232-8, (2010) (PubMed).
: "Phosphorylation analysis of primary human T lymphocytes using sequential IMAC and titanium oxide enrichment." in: Journal of proteome research, Vol. 7, Issue 12, pp. 5167-76, (2009) (PubMed).
: "The proteasome-associated deubiquitinating enzyme Usp14 is essential for the maintenance of synaptic ubiquitin levels and the development of neuromuscular junctions." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 29, Issue 35, pp. 10909-19, (2009) (PubMed).
: "USP14 inhibits ER-associated degradation via interaction with IRE1alpha." in: Biochemical and biophysical research communications, Vol. 379, Issue 4, pp. 995-1000, (2009) (PubMed).
: "Deubiquitination of CXCR4 by USP14 is critical for both CXCL12-induced CXCR4 degradation and chemotaxis but not ERK ativation." in: The Journal of biological chemistry, Vol. 284, Issue 9, pp. 5742-52, (2009) (PubMed).
: "Relative structural and functional roles of multiple deubiquitylating proteins associated with mammalian 26S proteasome." in: Molecular biology of the cell, Vol. 19, Issue 3, pp. 1072-82, (2008) (PubMed).
: "Yeast two-hybrid screens imply involvement of Fanconi anemia proteins in transcription regulation, cell signaling, oxidative metabolism, and cellular transport." in: Experimental cell research, Vol. 289, Issue 2, pp. 211-21, (2003) (PubMed).
: "Human and mouse proteases: a comparative genomic approach." in: Nature reviews. Genetics, Vol. 4, Issue 7, pp. 544-58, (2003) (PubMed).
Synonyme und alternative Namen zu USP14
ubiquitin specific peptidase 14 (USP14), peptidase C19 family protein (usp14), ubiquitin specific peptidase 14 (Usp14), ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase) (usp14), ubiquitin specific protease 14 (Bm1_28765), ubiquitin specific peptidase 14 S homeolog (usp14.S), ubiquitin specific peptidase 14 (usp14), universal stress protein (RR_RS06480), Ubiquitin carboxyl-terminal hydrolase 14 (usp-14), 2610005K12Rik, 2610037B11Rik, AW107924, ax, C78769, DDBDRAFT_0202821, DDBDRAFT_0237695, DDB_0202821, DDB_0237695, MGC69343, MGC81945, TGT, tgt, USP14, wu:fk63d09, zgc:55949Bezeichner auf Proteinebene für USP14
- deubiquitinating enzyme 14
- tRNA-guanine transglycosylase, 60-kD subunit
- ubiquitin carboxyl-terminal hydrolase 14
- ubiquitin specific protease 14 (tRNA-guanine transglycosylase)
- ubiquitin thioesterase 14
- ubiquitin thiolesterase 14
- ubiquitin-specific processing protease 14
- ubiquitin-specific-processing protease 14
- ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase)
- ubiquitin domain-containing protein
- ataxia
- dUB-type TGT for deubiquitinating enzyme
- ubiquitin specific protease 14
- universal stress protein
- queuine tRNA-ribosyltransferase
- ubiquitin carboxyl-terminal hydrolase 14-like
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