UVRAG Produkte
(UV Radiation Resistance Associated Gene (UVRAG))
Kategorien
This gene complements the ultraviolet sensitivity of xeroderma pigmentosum group C cells and encodes a protein with a C2 domain. The protein activates the Beclin1-PI(3)KC3 complex, promoting autophagy and suppressing the proliferation and tumorigenicity of human colon cancer cells. Chromosomal aberrations involving this gene are associated with left-right axis malformation and mutations in this gene have been associated with colon cancer. [provided by RefSeq, Jul 2008].
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Ausgewählte UVRAG Kategorien
UVRAG Antikörper
High quality antibodies with extensive validation data.
UVRAG Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene UVRAG Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB
Validierungen
- (1)
- (4)
Kat. Nr.
ABIN6150044
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IF, IHC
Validierungen
- (4)
Kat. Nr.
ABIN7175178
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human, Mouse
Applikation
WB, IF, IHC (p)
Validierungen
- (7)
- (3)
Kat. Nr.
ABIN388586
Menge
400 μL
Datenblatt
Datenblatt
Empfohlene UVRAG ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
Kat. Nr.
ABIN6201850
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene UVRAG Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1324875
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1324874
Menge
25 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Tobacco (Nicotiana tabacum)
Validierungen
Kat. Nr.
ABIN3096275
Menge
1 mg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren UVRAG Produkten
: "NLRX1 Negatively Regulates Group A Streptococcus Invasion and Autophagy Induction by Interacting With the Beclin 1-UVRAG Complex." in: Frontiers in cellular and infection microbiology, Vol. 8, pp. 403, (2019) (PubMed).: "The lncRNA HULC functions as an oncogene by targeting ATG7 and ITGB1 in epithelial ovarian carcinoma." in: Cell death & disease, Vol. 8, Issue 10, pp. e3118, (2018) (PubMed).
: "Acetylation of Beclin 1 inhibits autophagosome maturation and promotes tumour growth." in: Nature communications, Vol. 6, pp. 7215, (2015) (PubMed).
: "Autophagic induction of amyotrophic lateral sclerosis-linked Cu/Zn superoxide dismutase 1 G93A mutant in NSC34 cells." in: Neural regeneration research, Vol. 9, Issue 1, pp. 16-24, (2014) (PubMed).
: "Oncogenic B-RAF signaling in melanoma impairs the therapeutic advantage of autophagy inhibition." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 17, Issue 8, pp. 2216-26, (2011) (PubMed).
: "The RUN domain of rubicon is important for hVps34 binding, lipid kinase inhibition, and autophagy suppression." in: The Journal of biological chemistry, Vol. 286, Issue 1, pp. 185-91, (2011) (PubMed).
: "RalB and the exocyst mediate the cellular starvation response by direct activation of autophagosome assembly." in: Cell, Vol. 144, Issue 2, pp. 253-67, (2011) (PubMed).
: "Presenilin is necessary for efficient proteolysis through the autophagy-lysosome system in a ?-secretase-independent manner." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 31, Issue 8, pp. 2781-91, (2011) (PubMed).
: "Rubicon controls endosome maturation as a Rab7 effector." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 107, Issue 45, pp. 19338-43, (2010) (PubMed).
: "Biochemical isolation and characterization of the tubulovesicular LC3-positive autophagosomal compartment." in: The Journal of biological chemistry, Vol. 285, Issue 2, pp. 1371-83, (2010) (PubMed).
Synonyme und alternative Namen zu UVRAG
UV radiation resistance associated (UVRAG), UV radiation resistance associated gene (Uvrag), UV radiation resistance associated gene (uvrag), UV radiation resistance associated (Uvrag), UV radiation resistance associated S homeolog (uvrag.S), UV radiation resistance associated L homeolog (uvrag.L), UV radiation resistance associated (uvrag), UV-resistance associated gene (Uvrag), 9530039D02Rik, AI648770, BB124205, CG6116, DHTX, Dmel\\CG6116, MGC81810, MGC131135, p63, uvrag, UVRAG, Uvrag1, Uvragl, VPS38, zgc:56164Bezeichner auf Proteinebene für UVRAG
- UV radiation resistance-associated gene protein
- beclin 1 binding protein
- disrupted in heterotaxy
- UV radiation resistance associated
- UV radiation resistance associated gene
- UV radiation resistance-associated gene protein-like
- CG6116-PA
- CG6116-PB
- Uvrag-PA
- Uvrag-PB
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