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WFDC2 Produkte

(WAP Four-Disulfide Core Domain 2 (WFDC2))
This gene encodes a protein that is a member of the WFDC domain family. The WFDC domain, or WAP Signature motif, contains eight cysteines forming four disulfide bonds at the core of the protein, and functions as a protease inhibitor in many family members. This gene is expressed in pulmonary epithelial cells, and was also found to be expressed in some ovarian cancers. The encoded protein is a small secretory protein, which may be involved in sperm maturation. [provided by RefSeq, Jul 2008].

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Ausgewählte WFDC2 Kategorien

WFDC2 Antikörper

High quality antibodies with extensive validation data.

WFDC2 ELISA Kits

Reliable ELISA kits for a wide range of species.

WFDC2 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene WFDC2 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Mouse, Rat
Applikation ELISA, WB, IHC (p)
Validierungen
  • (6)
Kat. Nr. ABIN5519074
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Applikation ELISA, WB, IHC, IF
Validierungen
  • (4)
Kat. Nr. ABIN7175671
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, IHC, IHC (p)
Validierungen
  • (4)
Kat. Nr. ABIN1491389
Menge 100 μL
Datenblatt Datenblatt

Empfohlene WFDC2 ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6962650
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6960523
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Mouse
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6976023
Menge 96 tests
Datenblatt Datenblatt

Empfohlene WFDC2 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Dog
Source HEK-293 Cells
Validierungen
  • (2)
Kat. Nr. ABIN7274791
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
  • (1)
Kat. Nr. ABIN1325310
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
  • (1)
Kat. Nr. ABIN7125722
Menge 50 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren WFDC2 Produkten

Yang, Lu, Guo, Fellman, Ning, Lu, Menon, Kobayashi, Hanash, Celestino, Skates, Bast: "Human epididymis protein 4 antigen-autoantibody complexes complement cancer antigen 125 for detecting early-stage ovarian cancer." in: Cancer, (2019) (PubMed).

Dong, Liu, Li: "Value of HE4 Combined with Cancer Antigen 125 in the Diagnosis of Endometrial Cancer." in: Pakistan journal of medical sciences, Vol. 33, Issue 4, pp. 1013-1017, (2017) (PubMed).

Zhou, Lv, Shao, Xu, Luo, Zhang, Hu, Zhang, Luo, Fang, Wang, Duan, Huang: "Detection of Human Epididymis Protein 4 (HE4) in Human Serum Samples Using a Specific Monoclonal Antibody-Based Sandwich Enzyme-Linked Immunosorbent Assay (ELISA)." in: Journal of clinical laboratory analysis, Vol. 30, Issue 5, pp. 581-9, (2017) (PubMed).

Eaton, Shallcross, Mael, Mears, Minkoff, Scoville, Whelan: "Selection of DNA aptamers for ovarian cancer biomarker HE4 using CE-SELEX and high-throughput sequencing." in: Analytical and bioanalytical chemistry, (2015) (PubMed).

Moore, Hill, Horan, Yano, Kim, MacLaughlan, Lambert-Messerlian, Tseng, Padbury, Miller, Lange, Singh: "HE4 (WFDC2) gene overexpression promotes ovarian tumor growth." in: Scientific reports, Vol. 4, pp. 3574, (2014) (PubMed).

LeBleu, Teng, OConnell, Charytan, Müller, Müller, Sugimoto, Kalluri: "Identification of human epididymis protein-4 as a fibroblast-derived mediator of fibrosis." in: Nature medicine, Vol. 19, Issue 2, pp. 227-31, (2013) (PubMed).

Yuan, Duan, Yang, Luo, Xi: "Detection of serum human epididymis secretory protein 4 in patients with ovarian cancer using a label-free biosensor based on localized surface plasmon resonance." in: International journal of nanomedicine, Vol. 7, pp. 2921-8, (2012) (PubMed).

Huhtinen, Suvitie, Hiissa, Junnila, Huvila, Kujari, Setälä, Härkki, Jalkanen, Fraser, Mäkinen, Auranen, Poutanen, Perheentupa: "Serum HE4 concentration differentiates malignant ovarian tumours from ovarian endometriotic cysts." in: British journal of cancer, Vol. 100, Issue 8, pp. 1315-9, (2009) (PubMed).

Hellström, Raycraft, Hayden-Ledbetter, Ledbetter, Schummer, McIntosh, Drescher, Urban, Hellström: "The HE4 (WFDC2) protein is a biomarker for ovarian carcinoma." in: Cancer research, Vol. 63, Issue 13, pp. 3695-700, (2003) (PubMed).

Kirchhoff, Habben, Ivell, Krull: "A major human epididymis-specific cDNA encodes a protein with sequence homology to extracellular proteinase inhibitors." in: Biology of reproduction, Vol. 45, Issue 2, pp. 350-7, (1992) (PubMed).

Synonyme und alternative Namen zu WFDC2

WAP four-disulfide core domain 2 (WFDC2), WAP four-disulfide core domain 2 (wfdc2), WAP four-disulfide core domain 2 (Wfdc2), 1600023A02Rik, BE-20, CE4, dJ461P17.6, EDDM4, HE4, re4, si:ch211-153a8.3, WAP5, WFDC2, WFDC3

Bezeichner auf Proteinebene für WFDC2

  • WAP four-disulfide core domain 2
  • WAP four-disulfide core domain 3
  • WAP four-disulfide core domain protein 2
  • WAP domain containing protein HE4-V4
  • epididymal protein 4
  • epididymal secretory protein E4
  • epididymis-specific, whey-acidic protein type, four-disulfide core
  • major epididymis-specific protein E4
  • putative protease inhibitor WAP5
  • WAP domain-containing protein HE4
  • epididymal secretory protein 4
  • epididymal protein BE-20
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