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WHSC2 Produkte

(Wolf-Hirschhorn Syndrome Candidate 2 (WHSC2))

Kategorien

This gene is expressed ubiquitously with higher levels in fetal than in adult tissues. It encodes a protein sharing 93% sequence identity with the mouse protein. Wolf-Hirschhorn syndrome (WHS) is a malformation syndrome associated with a hemizygous deletion of the distal short arm of chromosome 4. This gene is mapped to the 165 kb WHS critical region, and may play a role in the phenotype of the WHS or Pitt-Rogers-Danks syndrome. The encoded protein is found to be capable of reacting with HLA-A2-restricted and tumor-specific cytotoxic T lymphocytes, suggesting a target for use in specific immunotherapy for a large number of cancer patients. This protein has also been shown to be a member of the NELF (negative elongation factor) protein complex that participates in the regulation of RNA polymerase II transcription elongation. [provided by RefSeq, Jul 2008].

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Ausgewählte WHSC2 Kategorien

WHSC2 Antikörper

High quality antibodies with extensive validation data.

WHSC2 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene WHSC2 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB, ELISA, IHC, FACS, ICC
Validierungen
  • (2)
  • (8)
Kat. Nr. ABIN1724801
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human, Rat
Applikation WB, ELISA, IHC, FACS, ICC
Validierungen
  • (2)
  • (8)
Kat. Nr. ABIN1724802
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human, Rat
Applikation WB, ELISA, IHC, FACS, IF/ICC
Validierungen
  • (7)
Kat. Nr. ABIN1846367
Menge 100 μL
Datenblatt Datenblatt

Empfohlene WHSC2 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1325326
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
  • (1)
Kat. Nr. ABIN7125741
Menge 50 μg
Datenblatt Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1325325
Menge 25 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren WHSC2 Produkten

Kerzendorfer, Hannes, Colnaghi, Abramowicz, Carpenter, Vermeesch, ODriscoll: "Characterizing the functional consequences of haploinsufficiency of NELF-A (WHSC2) and SLBP identifies novel cellular phenotypes in Wolf-Hirschhorn syndrome." in: Human molecular genetics, Vol. 21, Issue 10, pp. 2181-93, (2012) (PubMed).

Yung, Narita, Komori, Yamaguchi, Handa: "Cellular dynamics of the negative transcription elongation factor NELF." in: Experimental cell research, Vol. 315, Issue 10, pp. 1693-705, (2009) (PubMed).

Synonyme und alternative Namen zu WHSC2

Negative elongation factor A (Nelf-A), negative elongation factor complex member A (Nelfa), negative elongation factor complex member A (nelfa), negative elongation factor complex member A L homeolog (nelfa.L), negative elongation factor complex member A (NELFA), negative elongation factor complex member A, Whsc2 (Nelfa), BcDNA:SD07139, CG5874, Dmel\\CG5874, fi75f03, MGC85474, NELF, NELF-A, nelf-a, nelfa, p/okcl.15, Whsc2, whsc2, WHSC2, Whsc2h, wu:fi75f03

Bezeichner auf Proteinebene für WHSC2

  • CG5874-PA
  • CG5874-PB
  • NELF-A
  • Nelf-A-PA
  • Nelf-A-PB
  • negative elongation factor A
  • Wolf-Hirschhorn syndrome candidate 2 protein
  • Wolf-Hirschhorn syndrome candidate 2
  • negative elongation factor A-like
  • wolf-Hirschhorn syndrome candidate 2 protein
  • Wolf-Hirschhorn syndrome candidate 2 homolog
  • mWHSC2
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