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WNK4 Produkte

(WNK Lysine Deficient Protein Kinase 4 (WNK4))
This gene encodes a member of the WNK family of serine-threonine protein kinases. The kinase is part of the tight junction complex in kidney cells, and regulates the balance between NaCl reabsorption and K(+) secretion. The kinase regulates the activities of several types of ion channels, cotransporters, and exchangers involved in electrolyte flux in epithelial cells. Mutations in this gene result in pseudohypoaldosteronism type IIB.[provided by RefSeq, Sep 2009].

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Ausgewählte WNK4 Kategorien

WNK4 Antikörper

High quality antibodies with extensive validation data.

WNK4 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene WNK4 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation ELISA, IHC, IF
Validierungen
  • (3)
Kat. Nr. ABIN7169234
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Applikation ELISA, WB
Validierungen
  • (2)
Kat. Nr. ABIN528800
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Mouse
Applikation ELISA, WB
Validierungen
  • (1)
Kat. Nr. ABIN668526
Menge 100 μL
Datenblatt Datenblatt

Empfohlene WNK4 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1325354
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Mouse
Source Insect Cells
Validierungen
Kat. Nr. ABIN5509230
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Tobacco (Nicotiana tabacum)
Validierungen
Kat. Nr. ABIN3096394
Menge 1 mg
Datenblatt Datenblatt

Neueste Publikationen zu unseren WNK4 Produkten

Huguet, Le Dudal, Livrozet, Bazin, Frochot, Perez, Haymann, Brocheriou, Daudon, Letavernier: "High frequency and wide range of human kidney papillary crystalline plugs." in: Urolithiasis, (2018) (PubMed).

Kim, Yang, Kim, Kang, Kim, Cho: "Role of nitric oxide and WNK-SPAK/OSR1-KCC2 signaling in daily changes in GABAergic inhibition in the rat dorsal raphe neurons." in: Neuropharmacology, Vol. 135, pp. 355-367, (2018) (PubMed).

Bhuiyan, Song, Yuan, Begum, Kofler, Kahle, Yang, Lin, Alper, Subramanya, Sun: "WNK-Cab39-NKCC1 signaling increases the susceptibility to ischemic brain damage in hypertensive rats." in: Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, Vol. 37, Issue 8, pp. 2780-2794, (2017) (PubMed).

Li, Hatano, Xu, Wan, Yang, Weinstein, Palmer, Wang: "Gender difference in kidney electrolyte transport. I. Role of AT1a receptor in thiazide-sensitive Na+-Cl- cotransporter activity and expression in male and female mice." in: American journal of physiology. Renal physiology, Vol. 313, Issue 2, pp. F505-F513, (2017) (PubMed).

Andrukhova, Smorodchenko, Egerbacher, Streicher, Zeitz, Goetz, Shalhoub, Mohammadi, Pohl, Lanske, Erben: "FGF23 promotes renal calcium reabsorption through the TRPV5 channel." in: The EMBO journal, Vol. 33, Issue 3, pp. 229-46, (2014) (PubMed).

Ohno, Uchida, Ohashi, Nitta, Ohta, Chiga, Sasaki, Uchida: "Immunolocalization of WNK4 in mouse kidney." in: Histochemistry and cell biology, Vol. 136, Issue 1, pp. 25-35, (2011) (PubMed).

Uchida: "Pathophysiological roles of WNK kinases in the kidney." in: Pflügers Archiv : European journal of physiology, Vol. 460, Issue 4, pp. 695-702, (2010) (PubMed).

Subramanya, Liu, Ellison, Wade, Welling: "WNK4 diverts the thiazide-sensitive NaCl cotransporter to the lysosome and stimulates AP-3 interaction." in: The Journal of biological chemistry, Vol. 284, Issue 27, pp. 18471-80, (2009) (PubMed).

Song, Hu, Riazi, Tiwari, Wade, Ecelbarger: "Regulation of blood pressure, the epithelial sodium channel (ENaC), and other key renal sodium transporters by chronic insulin infusion in rats." in: American journal of physiology. Renal physiology, Vol. 290, Issue 5, pp. F1055-64, (2006) (PubMed).

Kahle, Gimenez, Hassan, Wilson, Wong, Forbush, Aronson, Lifton: "WNK4 regulates apical and basolateral Cl- flux in extrarenal epithelia." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 101, Issue 7, pp. 2064-9, (2004) (PubMed).

Synonyme und alternative Namen zu WNK4

WNK lysine deficient protein kinase 4 (WNK4), WNK lysine deficient protein kinase 4 (Wnk4), 2010002J11Rik, Ac2-059, PHA2B, Pha2b, PRKWNK4, Prkwnk4, WNK4

Bezeichner auf Proteinebene für WNK4

  • WNK lysine deficient protein kinase 4
  • protein kinase lysine-deficient 4
  • protein kinase with no lysine 4
  • serine/threonine-protein kinase WNK4
  • protein kinase, lysine deficient 4
  • WNK4 Ser/Thr kinase
  • protein kinase, lysine-deficient 4
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