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WWTR1 Produkte

(WW Domain Containing Transcription Regulator 1 (WWTR1))

Kategorien

This gene encodes a binding protein of the 14-3-3 family of proteins that regulate cell cycle progression, differentiation and apoptosis. The encoded protein is a transcriptional co-activator that binds to the PPXY motif present on transcription factors. The gene product contains a WW domain and, in the C-terminus, a conserved PDZ-binding motif. This gene is distinct from the gene encoding tafazzin. Both genes share the gene symbol Taz. Multiple transcript variants encoding different isoforms have been described. [provided by RefSeq, Mar 2010].

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Ausgewählte WWTR1 Kategorien

WWTR1 Antikörper

High quality antibodies with extensive validation data.

WWTR1 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene WWTR1 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB, IHC, IF
Validierungen
  • (7)
Kat. Nr. ABIN6150278
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Cow, Dog, Guinea Pig, Human, Mouse, Rabbit, Rat
Applikation WB
Validierungen
  • (5)
Kat. Nr. ABIN2779708
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, ELISA, IHC (p)
Validierungen
  • (3)
Kat. Nr. ABIN525503
Menge 100 μg
Datenblatt Datenblatt

Empfohlene WWTR1 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1325410
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1325412
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
Kat. Nr. ABIN2132584
Menge 100 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren WWTR1 Produkten

Hwang, Kim, Kim, Il Park, Oh, Moon, Byun, Jeong, Kim, Yaffe, Hwang, Hong: "TAZ couples Hippo/Wnt signalling and insulin sensitivity through Irs1 expression." in: Nature communications, Vol. 10, Issue 1, pp. 421, (2019) (PubMed).

Wu, Deng, Wang, Zhao, Wang, Rao, Xu, Zhou, Choi, Rizvi, Remke, Rubin, Johnson, Carroll, Stemmer-Rachamimov, Wu, Zheng, Xin, Ratner, Lu: "Programming of Schwann Cells by Lats1/2-TAZ/YAP Signaling Drives Malignant Peripheral Nerve Sheath Tumorigenesis." in: Cancer cell, Vol. 33, Issue 2, pp. 292-308.e7, (2018) (PubMed).

Yu, Huo, Liu, Deng, Szymanski, Li, Luo, Hong, Lin, Wang: "PGC-1α Controls Skeletal Stem Cell Fate and Bone-Fat Balance in Osteoporosis and Skeletal Aging by Inducing TAZ." in: Cell stem cell, Vol. 23, Issue 2, pp. 193-209.e5, (2018) (PubMed).

Xiang, Wang, Zhang, Piao, Muthusamy, Wang, Deng, Zhang, Kuang, Billadeau, Huang, Lai, Urrutia, Kang: "Vasodilator-stimulated phosphoprotein promotes liver metastasis of gastrointestinal cancer by activating a β1-integrin-FAK-YAP1/TAZ signaling pathway." in: NPJ precision oncology, Vol. 2, Issue 1, pp. 2, (2018) (PubMed).

Sero, Bakal: "Multiparametric Analysis of Cell Shape Demonstrates that β-PIX Directly Couples YAP Activation to Extracellular Matrix Adhesion." in: Cell systems, Vol. 4, Issue 1, pp. 84-96.e6, (2017) (PubMed).

Deng, Wu, Bai, Zhao, Wang, Wang, Xu, Sakabe, Zhou, Xin, Lu: "A reciprocal regulatory loop between TAZ/YAP and G-protein Gαs regulates Schwann cell proliferation and myelination." in: Nature communications, Vol. 8, pp. 15161, (2017) (PubMed).

Zhang, Wang, Ding, Damaolar, Li, Qiu, Yin: "Lentivirus-TAZ Administration Alleviates Osteoporotic Phenotypes in the Femoral Neck of Ovariectomized Rats." in: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, Vol. 38, Issue 1, pp. 283-94, (2016) (PubMed).

Slemmons, Crose, Rudzinski, Bentley, Linardic: "Role of the YAP Oncoprotein in Priming Ras-Driven Rhabdomyosarcoma." in: PLoS ONE, Vol. 10, Issue 10, pp. e0140781, (2015) (PubMed).

Xiang, Gilkes, Hu, Takano, Luo, Lu, Bullen, Samanta, Liang, Semenza: "Hypoxia-inducible factor 1 mediates TAZ expression and nuclear localization to induce the breast cancer stem cell phenotype." in: Oncotarget, Vol. 5, Issue 24, pp. 12509-27, (2015) (PubMed).

Xiang, Gilkes, Hu, Luo, Bullen, Liang, Semenza: "HIF-1α and TAZ serve as reciprocal co-activators in human breast cancer cells." in: Oncotarget, Vol. 6, Issue 14, pp. 11768-78, (2015) (PubMed).

Synonyme und alternative Namen zu WWTR1

WW domain containing transcription regulator 1 L homeolog (wwtr1.L), WW domain containing transcription regulator 1 (wwtr1), WW domain containing transcription regulator 1 (WWTR1), WW domain containing transcription regulator 1 (Wwtr1), 2310058J06Rik, 2610021I22Rik, C78399, TAZ, Taz, WWTR1

Bezeichner auf Proteinebene für WWTR1

  • WW domain containing transcription regulator 1
  • WW domain-containing transcription regulator protein 1
  • taz
  • WW domain-containing transcription regulator protein 1-like
  • transcriptional co-activator with PDZ-binding motif
  • transcriptional coactivator with PDZ-binding motif
  • transcriptional coactivator with PDZ binding motif
  • transcriptional co-activator with PDZ-binding motif (TA)Z
  • transcriptional co-activator with PDZ-binding motif (TAZ)
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