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XAF1 Produkte

(XiAP Associated Factor 1 (XAF1))

Kategorien

This gene encodes a protein which binds to and counteracts the inhibitory effect of a member of the IAP (inhibitor of apoptosis) protein family. IAP proteins bind to and inhibit caspases which are activated during apoptosis. The proportion of IAPs and proteins which interfere with their activity, such as the encoded protein, affect the progress of the apoptosis signaling pathway. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2012].

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Ausgewählte XAF1 Kategorien

XAF1 Antikörper

High quality antibodies with extensive validation data.

XAF1 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene XAF1 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Mouse, Rat
Applikation WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro)
Validierungen
  • (3)
Kat. Nr. ABIN674754
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB
Validierungen
  • (3)
Kat. Nr. ABIN527175
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Applikation ELISA, IHC, IF
Validierungen
  • (2)
Kat. Nr. ABIN7175921
Menge 100 μg
Datenblatt Datenblatt

Empfohlene XAF1 ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Mouse
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6971212
Menge 96 tests
Datenblatt Datenblatt

Empfohlene XAF1 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
  • (1)
Kat. Nr. ABIN7125752
Menge 50 μg
Datenblatt Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1325418
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1325416
Menge 10 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren XAF1 Produkten

Zhu, Li, Frontzek, Liu, Aguzzi: "SARM1 deficiency up-regulates XAF1, promotes neuronal apoptosis, and accelerates prion disease." in: The Journal of experimental medicine, Vol. 216, Issue 4, pp. 743-756, (2019) (PubMed).

Levin, Iannuzzi, Montgomery, Trudeau, Datta, Adrianto, Chitale, McKeigue, Rybicki: "Admixture fine-mapping in African Americans implicates XAF1 as a possible sarcoidosis risk gene." in: PLoS ONE, Vol. 9, Issue 3, pp. e92646, (2014) (PubMed).

Lunardi, Ala, Epping, Salmena, Clohessy, Webster, Wang, Mazzucchelli, Bianconi, Stack, Lis, Patnaik, Cantley, Bubley, Cordon-Cardo, Gerald, Montironi, Signoretti, Loda, Nardella, Pandolfi: "A co-clinical approach identifies mechanisms and potential therapies for androgen deprivation resistance in prostate cancer." in: Nature genetics, Vol. 45, Issue 7, pp. 747-55, (2013) (PubMed).

Chen, Wang, Huang, Lin, Wu, Sun, Chang, Feng: "Combination of DNA methylation inhibitor 5-azacytidine and arsenic trioxide has synergistic activity in myeloma." in: European journal of haematology, Vol. 82, Issue 3, pp. 176-83, (2009) (PubMed).

Kempkensteffen, Fritzsche, Johannsen, Weikert, Hinz, Dietel, Riener, Moch, Jung, Krause, Miller, Kristiansen: "Down-regulation of the pro-apoptotic XIAP associated factor-1 (XAF1) during progression of clear-cell renal cancer." in: BMC cancer, Vol. 9, pp. 276, (2009) (PubMed).

Davies, Sarkar, Rubinsztein: "Wild-type PABPN1 is anti-apoptotic and reduces toxicity of the oculopharyngeal muscular dystrophy mutation." in: Human molecular genetics, Vol. 17, Issue 8, pp. 1097-108, (2008) (PubMed).

Straszewski-Chavez, Visintin, Karassina, Los, Liston, Halaban, Fadiel, Mor: "XAF1 mediates tumor necrosis factor-alpha-induced apoptosis and X-linked inhibitor of apoptosis cleavage by acting through the mitochondrial pathway." in: The Journal of biological chemistry, Vol. 282, Issue 17, pp. 13059-72, (2007) (PubMed).

Xia, Novak, Lewis, Duckett, Phillips: "Xaf1 can cooperate with TNFalpha in the induction of apoptosis, independently of interaction with XIAP." in: Molecular and cellular biochemistry, Vol. 286, Issue 1-2, pp. 67-76, (2006) (PubMed).

Heiser, Labi, Erlacher, Villunger: "The Bcl-2 protein family and its role in the development of neoplastic disease." in: Experimental gerontology, Vol. 39, Issue 8, pp. 1125-35, (2004) (PubMed).

Wang, Zhu, Wang, Hagberg, Korhonen, Sandberg, Lindholm, Blomgren: "X-linked inhibitor of apoptosis (XIAP) protein protects against caspase activation and tissue loss after neonatal hypoxia-ischemia." in: Neurobiology of disease, Vol. 16, Issue 1, pp. 179-89, (2004) (PubMed).

Synonyme und alternative Namen zu XAF1

XIAP associated factor 1 (xaf1), XIAP associated factor 1 (XAF1), XIAP associated factor 1 (Xaf1), BIRC4BP, Fbxo39, HSXIAPAF1, XIAPAF1

Bezeichner auf Proteinebene für XAF1

  • XIAP-associated factor 1
  • BIRC4 binding protein
  • BIRC4-binding protein
  • F-box protein 39
  • novel TRAF-type zinc finger protein
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