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XIAP Produkte

(X-Linked Inhibitor of Apoptosis (XIAP))

Kategorien

This gene encodes a protein that belongs to a family of apoptotic suppressor proteins. Members of this family share a conserved motif termed, baculovirus IAP repeat, which is necessary for their anti-apoptotic function. This protein functions through binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2 and inhibits apoptosis induced by menadione, a potent inducer of free radicals, and interleukin 1-beta converting enzyme. This protein also inhibits at least two members of the caspase family of cell-death proteases, caspase-3 and caspase-7. Mutations in this gene are the cause of X-linked lymphoproliferative syndrome. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 2 and 11.[provided by RefSeq, Feb 2011].

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Ausgewählte XIAP Kategorien

XIAP Antikörper

High quality antibodies with extensive validation data.

XIAP ELISA Kits

Reliable ELISA kits for a wide range of species.

XIAP Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene XIAP Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB, IF, IHC (p), ICC
Validierungen
  • (5)
Kat. Nr. ABIN2854771
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human, Mouse, Rat
Applikation WB, ELISA, IHC, IF, ICC
Validierungen
  • (5)
Kat. Nr. ABIN6256441
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human, Mouse, Rat
Applikation WB, ELISA, IHC (p), FACS, IF (cc), IF (p), IHC (fro)
Validierungen
  • (4)
  • (3)
Kat. Nr. ABIN674364
Menge 100 μL
Datenblatt Datenblatt

Empfohlene XIAP ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
  • (1)
Kat. Nr. ABIN6960570
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6971208
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human, Mouse
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN625470
Menge 96 tests
Datenblatt Datenblatt

Empfohlene XIAP Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
  • (1)
Kat. Nr. ABIN7125749
Menge 50 μg
Datenblatt Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1325435
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
Kat. Nr. ABIN7505227
Menge 100 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren XIAP Produkten

Wu, Fan, Ma, Liu, Wang, Song, Lv, Pan, Zhang, Wang: "Distinctive expression signatures of serum microRNAs in ischaemic stroke and transient ischaemic attack patients." in: Thrombosis and haemostasis, Vol. 117, Issue 5, pp. 992-1001, (2018) (PubMed).

Ng, Hang, Sawyer, Neitzel, Crispi, Rose, Popay, Zhong, Lee, Tansey, Huppert, Lee: "Phosphorylation of XIAP at threonine 180 controls its activity in Wnt signaling." in: Journal of cell science, Vol. 131, Issue 10, (2018) (PubMed).

Lee, Lee, Kim, Park, Choi, Shin, Shin: "Low-level light emitting diode (LED) therapy suppresses inflammasome-mediated brain damage in experimental ischemic stroke." in: Journal of biophotonics, (2017) (PubMed).

Wei, Gao, Zheng, Zhang, Liu, Yang, Teng, Hou, Yin, Zou: "Protective Effects of Fucoidan on Aβ25-35 and d-Gal-Induced Neurotoxicity in PC12 Cells and d-Gal-Induced Cognitive Dysfunction in Mice." in: Marine drugs, Vol. 15, Issue 3, (2017) (PubMed).

De Toni, Ziesch, Rizzani, Török, Hocke, Lü, Wang, Hucl, Göke, Bruns, Gallmeier: "Inactivation of BRCA2 in human cancer cells identifies a subset of tumors with enhanced sensitivity towards death receptor-mediated apoptosis." in: Oncotarget, Vol. 7, Issue 8, pp. 9477-90, (2017) (PubMed).

Sun, Liu, Zou, Lan, Sun, Wang, Zhao, Jiang, Liu: "Mechanisms underlying 3-bromopyruvate-induced cell death in colon cancer." in: Journal of bioenergetics and biomembranes, (2015) (PubMed).

Chen, Mao, Qiu, Liu: "Gene transfection mediated by polyethyleneimine-polyethylene glycol nanocarrier prevents cisplatin-induced spiral ganglion cell damage." in: Neural regeneration research, Vol. 10, Issue 3, pp. 425-31, (2015) (PubMed).

Jin, Lan, Han, Sun, Liu, Zhang, Liu, Zhang, Hu, Liu, Wang: "Smac mimetic?induced caspase?independent necroptosis requires RIP1 in breast cancer." in: Molecular medicine reports, (2015) (PubMed).

Chen, Xie, Zhao, Wang, Bai, Yin, Jiang, Xie, Jia, Huang et al.: "Ampelopsin induces apoptosis by regulating multiple c?Myc/S?phase kinase?associated protein 2/F?box and WD repeat?containing protein 7/histone deacetylase 2 pathways in human lung adenocarcinoma ..." in: Molecular medicine reports, Vol. 11, Issue 1, pp. 105-12, (2014) (PubMed).

Chen, Bai, Zhong, Xie, Long, Yang, Wu, Jia, Wang: "Wogonin has multiple anti-cancer effects by regulating c-Myc/SKP2/Fbw7? and HDAC1/HDAC2 pathways and inducing apoptosis in human lung adenocarcinoma cell line A549." in: PLoS ONE, Vol. 8, Issue 11, pp. e79201, (2013) (PubMed).

Synonyme und alternative Namen zu XIAP

X-linked inhibitor of apoptosis (XIAP), X-linked inhibitor of apoptosis (xiap), X-linked inhibitor of apoptosis L homeolog (xiap.L), X-linked inhibitor of apoptosis (Xiap), 1110015C02Rik, Aipa, API3, api3, Api3, BIRC4, birc4, Birc4, BIRC8, fb73d01, hIAP-3, hIAP3, IAP-3, IAP3, ILP-1, ILP1, ilp1, MIHA, miha, mXIAP, riap3, wu:fb73d01, XLP2, xlp2, xxiap, zgc:91873

Bezeichner auf Proteinebene für XIAP

  • E3 ubiquitin-protein ligase XIAP
  • IAP-like protein
  • X-linked IAP
  • baculoviral IAP repeat-containing protein 4
  • inhibitor of apoptosis protein 3
  • Baculoviral IAP repeat-containing protein 4
  • X-linked inhibitor of apoptosis protein
  • baculoviral IAP repeat-containing 4
  • baculoviral IAP-repeat containing protein 4
  • IAP homolog A
  • IAP-3
  • apoptosis inhibitor 3
  • mIAP-3
  • mIAP3
  • RIAP-3
  • apoptosis inhibitor protein 3
  • baculoviral IAP repeat containing 8
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