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XPO1 Produkte

(Exportin 1 (XPO1))
The protein encoded by this gene mediates leucine-rich nuclear export signal (NES)-dependent protein transport. Exportin 1 specifically inhibits the nuclear export of Rev and U snRNAs. It is involved in the control of several cellular processes by controlling the localization of cyclin B, MPAK, and MAPKAP kinase 2. This protein also regulates NFAT and AP-1. [provided by RefSeq, Jul 2008].

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Ausgewählte XPO1 Kategorien

XPO1 Antikörper

High quality antibodies with extensive validation data.

XPO1 ELISA Kits

Reliable ELISA kits for a wide range of species.

XPO1 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene XPO1 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human, Mouse, Rat
Applikation WB, IHC (p), ICC
Validierungen
  • (7)
Kat. Nr. ABIN4886771
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, ELISA, IHC, IF
Validierungen
  • (4)
Kat. Nr. ABIN7152317
Menge 100 μg
Datenblatt Datenblatt

Applikation WB, IHC
Validierungen
  • (1)
  • (4)
Kat. Nr. ABIN2778849
Menge 100 μL
Datenblatt Datenblatt

Empfohlene XPO1 ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
  • (1)
Kat. Nr. ABIN6955675
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Mouse
Analytical Method
Validierungen
Kat. Nr. ABIN1132695
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Rat
Analytical Method
Validierungen
Kat. Nr. ABIN1132696
Menge 96 tests
Datenblatt Datenblatt

Empfohlene XPO1 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
  • (1)
Kat. Nr. ABIN7477806
Menge 2 μg
Datenblatt Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
Kat. Nr. ABIN7413031
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Source Tobacco (Nicotiana tabacum)
Validierungen
Kat. Nr. ABIN3096383
Menge 1 mg
Datenblatt Datenblatt

Neueste Publikationen zu unseren XPO1 Produkten

Kalita, Kapinos, Zheng, Rencurel, Zilman, Lim: "Karyopherin enrichment and compensation fortifies the nuclear pore complex against nucleocytoplasmic leakage." in: The Journal of cell biology, Vol. 221, Issue 3, (2022) (PubMed).

Seervi, Sumi, Chandrasekharan, Sharma, SanthoshKumar: "Molecular profiling of anastatic cancer cells: potential role of the nuclear export pathway." in: Cellular oncology (Dordrecht), Vol. 42, Issue 5, pp. 645-661, (2020) (PubMed).

Steyaert, Scheveneels, Vanneste, Van Damme, Robberecht, Callaerts, Bogaert, Van Den Bosch: "FUS-induced neurotoxicity in Drosophila is prevented by downregulating nucleocytoplasmic transport proteins." in: Human molecular genetics, Vol. 27, Issue 23, pp. 4103-4116, (2019) (PubMed).

García-Aguirre, Alamillo-Iniesta, Rodríguez-Pérez, Vélez-Aguilera, Amaro-Encarnación, Jiménez-Gutiérrez, Vásquez-Limeta, Samuel Laredo-Cisneros, Morales-Lázaro, Tiburcio-Félix, Ortega, Magaña, Winder et al.: "Enhanced nuclear protein export in premature aging and rescue of the progeria phenotype by modulation of CRM1 activity. ..." in: Aging cell, Vol. 18, Issue 5, pp. e13002, (2019) (PubMed).

Vélez-Aguilera, de Dios Gómez-López, Jiménez-Gutiérrez, Vásquez-Limeta, Laredo-Cisneros, Gómez, Winder, Cisneros: "Control of nuclear β-dystroglycan content is crucial for the maintenance of nuclear envelope integrity and function." in: Biochimica et biophysica acta. Molecular cell research, Vol. 1865, Issue 2, pp. 406-420, (2018) (PubMed).

Seipel, Marques, Bozzini, Meinken, Mueller, Pabst: "Inactivation of the p53-KLF4-CEBPA Axis in Acute Myeloid Leukemia." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 22, Issue 3, pp. 746-56, (2016) (PubMed).

Oka, Mura, Yamada, Sangel, Hirata, Maehara, Kawakami, Tachibana, Ohkawa, Kimura, Yoneda: "Chromatin-prebound Crm1 recruits Nup98-HoxA9 fusion to induce aberrant expression of Hox cluster genes." in: eLife, Vol. 5, pp. e09540, (2016) (PubMed).

Vercruysse, De Bie, Neggers, Jacquemyn, Vanstreels, Schmid-Burgk, Hornung, Baloglu, Landesman, Senapedis, Shacham, Dagklis, Cools, Daelemans: "The second-generation exportin-1 inhibitor KPT-8602 demonstrates potent activity against acute lymphoblastic leukemia." in: Clinical cancer research : an official journal of the American Association for Cancer Research, (2016) (PubMed).

Bagheri, Badduke, Qiao, Colnaghi, Abramowicz, Alcantara, Dunham, Wen, Wildin, Nowaczyk, Eichmeyer, Lehman, Maranda, Martell, Shan, Lewis, ODriscoll, Gregory-Evans, Rajcan-Separovic: "Identifying candidate genes for 2p15p16.1 microdeletion syndrome using clinical, genomic, and functional analysis." in: JCI insight, Vol. 1, Issue 3, pp. e85461, (2016) (PubMed).

Sharma, Åkerström, Sharma, Chow, Teow, Abrenica, Booth, Booth, Mirazimi, Lal: "SARS-CoV 9b protein diffuses into nucleus, undergoes active Crm1 mediated nucleocytoplasmic export and triggers apoptosis when retained in the nucleus." in: PLoS ONE, Vol. 6, Issue 5, pp. e19436, (2011) (PubMed).

Synonyme und alternative Namen zu XPO1

embargoed (emb), exportin 1 (cgd3_3060), exportin 1 (Tc00.1047053511725.150), exportin 1 (Tb11.01.5940), exportin 1 (BBOV_II007220), putative exportin 1 (LMJF_32_1100), chromosome region maintenance protein 1 (xpo1), exportin 1 (Xpo1), exportin 1 (XPO1), exportin-1 (LOC100165622), exportin 1 (CRM1 homolog, yeast) (XPO1), exportin-1 (LOC100633509), exportin 1 S homeolog (xpo1.S), 18.m06600, AA420417, CG13387, CRM1, Crm1, crm1, DCRM1, dCRM1, DDBDRAFT_0183812, DDBDRAFT_0234066, DDB_0183812, DDB_0234066, Dmel\\CG13387, Emb, emb, exp1, Exp1, exportin-1, l(2)k16715, LOC100220104, Xpo, XPO-1, XPO1, Xpo1

Bezeichner auf Proteinebene für XPO1

  • CG13387-PA
  • Exportin-1
  • chromosomal region maintenance 1
  • emb-PA
  • exportin
  • exportin 1
  • exportin-1
  • exportin 1 (CRM1 homolog, yeast)
  • exportin 1-like
  • exportin-1-like
  • CRM1, yeast, homolog
  • chromosome region maintenance 1 protein homolog
  • exportin 1 (CRM1, yeast, homolog)
  • exportin-1 (required for chromosome region maintenance)
  • nuclear export factor CRM1
  • CRM1/XPO1 protein
  • exp1
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