XRCC4 Produkte
(X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 4 (XRCC4))
Kategorien
The protein encoded by this gene functions together with DNA ligase IV and the DNA-dependent protein kinase in the repair of DNA double-strand break by non-homologous end joining and the completion of V(D)J recombination events. The non-homologous end-joining pathway is required both for normal development and for suppression of tumors. This gene functionally complements XR-1 Chinese hamster ovary cell mutant, which is impaired in DNA double-strand breaks produced by ionizing radiation and restriction enzymes. Alternative transcription initiation and alternative splicing generates several transcript variants. [provided by RefSeq, Sep 2008].
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Ausgewählte XRCC4 Kategorien
XRCC4 Antikörper
High quality antibodies with extensive validation data.
XRCC4 ELISA Kits
Reliable ELISA kits for a wide range of species.
XRCC4 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene XRCC4 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, IHC, IF
Validierungen
- (2)
- (7)
Kat. Nr.
ABIN3022382
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IF, IHC (p)
Validierungen
- (1)
- (5)
Kat. Nr.
ABIN1327721
Menge
50 μL
Datenblatt
Datenblatt
Reaktivität
Human, Mouse, Rat
Applikation
IHC, IF
Validierungen
- (4)
Kat. Nr.
ABIN7259376
Menge
200 μL
Datenblatt
Datenblatt
Empfohlene XRCC4 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Qualitative Cell ELISA
Validierungen
Kat. Nr.
ABIN1381600
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene XRCC4 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1325469
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1325471
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
HEK-293 Cells
Validierungen
- (1)
- (1)
Kat. Nr.
ABIN2735698
Menge
20 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren XRCC4 Produkten
: "Histone H3K27 methylation modulates the dynamics of FANCD2 on chromatin to facilitate NHEJ and genome stability." in: Journal of cell science, Vol. 131, Issue 12, (2018) (PubMed).: "Quantitative proteomic analysis revealed changes in protein synthesis and mitochondrial functions after acute DNA damage in mouse neural stem cells." in: Neuroscience letters, Vol. 653, pp. 355-361, (2018) (PubMed).
: "Classical non-homologous end-joining pathway utilizes nascent RNA for error-free double-strand break repair of transcribed genes." in: Nature communications, Vol. 7, pp. 13049, (2018) (PubMed).
: "Impaired DNA double-strand break repair contributes to the age-associated rise of genomic instability in humans." in: Cell death and differentiation, Vol. 23, Issue 11, pp. 1765-1777, (2017) (PubMed).
: "Protein phosphatase 1 and phosphatase 1 nuclear targeting subunit-dependent regulation of DNA-dependent protein kinase and non-homologous end joining." in: Nucleic acids research, Vol. 45, Issue 18, pp. 10583-10594, (2017) (PubMed).
: "A localized nucleolar DNA damage response facilitates recruitment of the homology-directed repair machinery independent of cell cycle stage." in: Genes & development, Vol. 29, Issue 11, pp. 1151-63, (2015) (PubMed).
: "Organization and dynamics of the nonhomologous end-joining machinery during DNA double-strand break repair." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 112, Issue 20, pp. E2575-84, (2015) (PubMed).
: "A stress-induced cellular aging model with postnatal neural stem cells." in: Cell death & disease, Vol. 5, pp. e1116, (2014) (PubMed).
: "Quantification of XRCC and DNA-PK proteins in cancer cell lines and human tumors by LC-MS/MS." in: Bioanalysis, Vol. 6, Issue 22, pp. 2969-83, (2014) (PubMed).
: "A regulatory role for the cohesin loader NIPBL in nonhomologous end joining during immunoglobulin class switch recombination." in: The Journal of experimental medicine, Vol. 210, Issue 12, pp. 2503-13, (2013) (PubMed).
Synonyme und alternative Namen zu XRCC4
X-ray repair cross complementing 4 (XRCC4), X-ray repair complementing defective repair in Chinese hamster cells 4 (xrcc4), X-ray repair complementing defective repair in Chinese hamster cells 4 L homeolog (xrcc4.L), DNA ligase IV-binding protein (XRCC4), X-ray repair complementing defective repair in Chinese hamster cells 4 (Xrcc4), X-ray repair cross complementing 4 (Xrcc4), 2310057B22Rik, AW413319, AW545101, homolog of human DNA ligase iv-binding protein XRCC4, MGC81443, zgc:73312Bezeichner auf Proteinebene für XRCC4
- DNA repair protein XRCC4
- X-ray repair complementing defective repair in Chinese hamster cells 4
- DNA-repair protein XRCC4
- X-ray repair cross complementing protein 4
- X-ray repair cross-complementing protein 4
- X-ray repair, complementing defective, repair in Chinese hamster
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