XRCC5 Produkte
(X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 5 (Double-Strand-Break Rejoining) (XRCC5))
Kategorien
The protein encoded by this gene is the 80-kilodalton subunit of the Ku heterodimer protein which is also known as ATP-dependant DNA helicase II or DNA repair protein XRCC5. Ku is the DNA-binding component of the DNA-dependent protein kinase, and it functions together with the DNA ligase IV-XRCC4 complex in the repair of DNA double-strand break by non-homologous end joining and the completion of V(D)J recombination events. This gene functionally complements Chinese hamster xrs-6, a mutant defective in DNA double-strand break repair and in ability to undergo V(D)J recombination. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. [provided by RefSeq, Jul 2008].
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Ausgewählte XRCC5 Kategorien
XRCC5 Antikörper
High quality antibodies with extensive validation data.
XRCC5 ELISA Kits
Reliable ELISA kits for a wide range of species.
XRCC5 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene XRCC5 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, IHC, IF, IP
Validierungen
- (2)
- (12)
Kat. Nr.
ABIN6150309
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IF, IHC (p)
Validierungen
- (3)
- (6)
Kat. Nr.
ABIN563391
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human, Mouse
Applikation
WB, IHC, ELISA, FACS, ICC
Validierungen
- (2)
- (5)
Kat. Nr.
ABIN969463
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene XRCC5 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6971209
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6960572
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6960573
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene XRCC5 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1325473
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
- (1)
Kat. Nr.
ABIN5710636
Menge
100 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren XRCC5 Produkten
: "Downregulation of TMPRSS4 Enhances Triple-Negative Breast Cancer Cell Radiosensitivity Through Cell Cycle and Cell Apoptosis Process Impairment." in: Asian Pacific journal of cancer prevention : APJCP, Vol. 20, Issue 12, pp. 3679-3687, (2020) (PubMed).: "Histone H3K27 methylation modulates the dynamics of FANCD2 on chromatin to facilitate NHEJ and genome stability." in: Journal of cell science, Vol. 131, Issue 12, (2018) (PubMed).
: "BCL2-overexpressing prostate cancer cells rely on PARP1-dependent end-joining and are sensitive to combined PARP inhibitor and radiation therapy." in: Cancer letters, Vol. 423, pp. 60-70, (2018) (PubMed).
: "Impaired DNA double-strand break repair contributes to the age-associated rise of genomic instability in humans." in: Cell death and differentiation, Vol. 23, Issue 11, pp. 1765-1777, (2017) (PubMed).
: "Influence of XRCC4 expression in esophageal cancer cells on the response to radiotherapy." in: Medical molecular morphology, Vol. 50, Issue 1, pp. 25-33, (2016) (PubMed).
: "Expression of Ku70 predicts results of radiotherapy in prostate cancer." in: Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], Vol. 193, Issue 1, pp. 29-37, (2016) (PubMed).
: "Dual functions of the homeoprotein DLX4 in modulating responsiveness of tumor cells to topoisomerase II-targeting drugs." in: Cancer research, Vol. 73, Issue 2, pp. 1000-10, (2013) (PubMed).
: "Serum anti-Ku86 is a potential biomarker for early detection of hepatitis C virus-related hepatocellular carcinoma." in: Biochemical and biophysical research communications, Vol. 421, Issue 4, pp. 837-43, (2012) (PubMed).
: "Ku proteins interact with activator protein-2 transcription factors and contribute to ERBB2 overexpression in breast cancer cell lines." in: Breast cancer research : BCR, Vol. 11, Issue 6, pp. R83, (2010) (PubMed).
: "The cytoprotective drug amifostine modifies both expression and activity of the pro-angiogenic factor VEGF-A." in: BMC medicine, Vol. 8, pp. 19, (2010) (PubMed).
Synonyme und alternative Namen zu XRCC5
X-ray repair cross complementing 5 (XRCC5), X-ray repair complementing defective repair in Chinese hamster cells 5 (Xrcc5), X-ray repair cross complementing 5 (Xrcc5), X-ray repair complementing defective repair in Chinese hamster cells 5 L homeolog (xrcc5.L), AI314015, KARP-1, KARP1, Ku80, KU80, Ku86, KUB2, Kup80, NFIV, XRCC5, xrcc5-aBezeichner auf Proteinebene für XRCC5
- Ku autoantigen
- X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining; Ku autoantigen, 80kDa)
- X-ray repair protein
- X-ray repair cross-complementing protein 5
- X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)
- ATP-dependent DNA helicase II
- ATP-dependent DNA helicase 2 subunit 2-like
- x-ray repair cross-complementing protein 5-like
- ATP-dependent DNA helicase 2 subunit 2
- ATP-dependent DNA helicase II 80 kDa subunit
- CTC box-binding factor 85 kDa subunit
- CTC85
- CTCBF
- DNA repair protein XRCC5
- Ku p80
- ku autoantigen protein p86 homolog
- nuclear factor IV
- Ku autoantigen, 80kD)
- X-ray repair cross complementation (double-strand-break rejoining
- X-ray repair cross complementation (double-strand-break rejoining; Ku autoantigen, 80kD)
- 86 kDa subunit of Ku antigen
- Ku autoantigen, 80kDa
- Ku86 autoantigen related protein 1
- TLAA
- lupus Ku autoantigen protein p86
- thyroid-lupus autoantigen
- X-ray repair complementing defective repair in Chinese hamster cells 5
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