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YARS Produkte

(Tyrosyl-tRNA Synthetase (Yars))

Kategorien

Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Tyrosyl-tRNA synthetase belongs to the class I tRNA synthetase family. Cytokine activities have also been observed for the human tyrosyl-tRNA synthetase, after it is split into two parts, an N-terminal fragment that harbors the catalytic site and a C-terminal fragment found only in the mammalian enzyme. The N-terminal fragment is an interleukin-8-like cytokine, whereas the released C-terminal fragment is an EMAP II-like cytokine. [provided by RefSeq, Jul 2008].

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Ausgewählte YARS Kategorien

YARS Antikörper

High quality antibodies with extensive validation data.

YARS Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene YARS Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB, IHC, IP, ICC
Validierungen
  • (7)
Kat. Nr. ABIN7443434
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, ELISA, IHC, IF
Validierungen
  • (5)
Kat. Nr. ABIN7173996
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, ELISA
Validierungen
  • (2)
  • (4)
Kat. Nr. ABIN563694
Menge 50 μg
Datenblatt Datenblatt

Empfohlene YARS Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
  • (1)
Kat. Nr. ABIN7125569
Menge 50 μg
Datenblatt Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1325501
Menge 25 μg
Datenblatt Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
Kat. Nr. ABIN2132594
Menge 50 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren YARS Produkten

Zhang, Zhai, Tang, Cheng, Li, Wang, Zhu: "Quantitative proteome-based systematic identification of SIRT7 substrates." in: Proteomics, Vol. 17, Issue 13-14, (2017) (PubMed).

Wei, Xu, Liu, Lo, Ye, Lau, Wang, Zhou, Nangle, Yang, Zhang, Schimmel: "Alternative splicing creates two new architectures for human tyrosyl-tRNA synthetase." in: Nucleic acids research, Vol. 44, Issue 3, pp. 1247-55, (2016) (PubMed).

Niehues, Bussmann, Steffes, Erdmann, Köhrer, Sun, Wagner, Schäfer, Wang, Koerdt, Stum, RajBhandary, Thomas, Aberle, Burgess, Yang, Dieterich, Storkebaum: "Impaired protein translation in Drosophila models for Charcot-Marie-Tooth neuropathy caused by mutant tRNA synthetases." in: Nature communications, Vol. 6, pp. 7520, (2015) (PubMed).

Storkebaum, Leitão-Gonçalves, Godenschwege, Nangle, Mejia, Bosmans, Ooms, Jacobs, Van Dijck, Yang, Schimmel, Norga, Timmerman, Callaerts, Jordanova: "Dominant mutations in the tyrosyl-tRNA synthetase gene recapitulate in Drosophila features of human Charcot-Marie-Tooth neuropathy." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 106, Issue 28, pp. 11782-7, (2009) (PubMed).

Yang, Kapoor, Otero, Slike, Tsuruta, Frausto, Bates, Ewalt, Cheresh, Schimmel: "Gain-of-function mutational activation of human tRNA synthetase procytokine." in: Chemistry & biology, Vol. 14, Issue 12, pp. 1323-33, (2007) (PubMed).

Jordanova, Irobi, Thomas, Van Dijck, Meerschaert, Dewil, Dierick, Jacobs, De Vriendt, Guergueltcheva, Rao, Tournev, Gondim, DHooghe, Van Gerwen, Callaerts, Van Den Bosch, Timmermans, Robberecht et al.: "Disrupted function and axonal distribution of mutant tyrosyl-tRNA synthetase in dominant intermediate Charcot-Marie-Tooth neuropathy. ..." in: Nature genetics, Vol. 38, Issue 2, pp. 197-202, (2006) (PubMed).

Bonnefond, Fender, Rudinger-Thirion, Giegé, Florentz, Sissler: "Toward the full set of human mitochondrial aminoacyl-tRNA synthetases: characterization of AspRS and TyrRS." in: Biochemistry, Vol. 44, Issue 12, pp. 4805-16, (2005) (PubMed).

Synonyme und alternative Namen zu YARS

tyrosyl-tRNA synthetase (YARS), tyrosyl-tRNA synthetase (Yars), tyrosyl-tRNA synthetase (yars), tyrosyl-tRNA synthetase L homeolog (yars.L), tyrosyl-tRNA synthetase, putative (MAL8P1.125), tyrosine--tRNA ligase (MEFER_RS04475), Tyrosyl-tRNA synthetase (TyrRS), tyrosine--tRNA ligase, cytoplasmic (LOC413909), tyrosine--tRNA ligase, cytoplasmic (LOC100163888), tyrosyl-tRNA synthetase (LOC100282315), AL024047, anon-EST:Posey261, AU018965, cb204, CG4561, CMTDIC, cmtdic, Dmel\\CG4561, dYARS, GB10789, TYRRS, tyrrs, TyrRS, wu:fk52b08, YARS, YRS, yrs, YTS, yts

Bezeichner auf Proteinebene für YARS

  • tyrosine tRNA ligase 1, cytoplasmic
  • tyrosine--tRNA ligase, cytoplasmic
  • tyrosyl--tRNA ligase
  • tyrosyl-tRNA synthetase, cytoplasmic
  • Tyrosyl-tRNA synthetase, cytoplasmic
  • tyrRS
  • tyrosyl-tRNA synthetase
  • Aats-tyr-PA
  • CG4561-PA
  • ACYPI004940
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