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ZIC1-3 Antikörper (C-Term)

Zic1/2/3 Reaktivität: Human IHC, WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN351417
  • Target
    ZIC1-3 (Zic1/2/3) (Zic Family Member 1/2/3 (Zic1/2/3))
    Bindungsspezifität
    C-Term
    Reaktivität
    Human
    Wirt
    Kaninchen
    Klonalität
    Polyklonal
    Applikation
    Immunohistochemistry (IHC), Western Blotting (WB)
    Spezifität
    Specific for ZIC1, 2, 3.
    Kreuzreaktivität
    Human, Maus, Ratte
    Kreuzreaktivität (Details)
    Other species not yet tested.
    Aufreinigung
    IgG
    Immunogen
    A synthetic peptide from c-terminal region of human ZIC3 (Zinc finger protein ZIC 3) conjugated to an immunogenic carrier protein was used as the antigen. The peptide is homologous in many species including rat and mouse.
    Isotyp
    IgG
  • Applikationshinweise
    IHC, WB. A concentration of 10-50 μg,ml is recommended. The optimal concentration should be determined by the end user. Not yet tested in other applications.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Reconstitute in 500 μL of sterile water. Centrifuge to remove any insoluble material.
    Handhabung
    Avoid freeze and thaw cycles.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
    Haltbarkeit
    12 months
  • Target
    ZIC1-3 (Zic1/2/3) (Zic Family Member 1/2/3 (Zic1/2/3))
    Andere Bezeichnung
    ZIC1-3
    Hintergrund
    Function: Probably functions as a transcription factor in the earliest stages of the left-right (LR) body axis formation. Defects in ZIC3 are the cause of X-linked visceral heterotaxy (HTX1). HTX1 is a disease characterized by congenital heart disease and alterations of visceral situs, including asplenia or polysplenia, symmetric liver, intestinal malrotation, and abnormal lung lobation.,Stem Cells,HTX, HTX1, Zic family member 3 (odd-paired Drosophila homolog heterotaxy 1), Zinc finger protein ZIC 3 (Zinc finger protein of the cerebellum 3), ZNF203
    UniProt
    O60481
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