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ZMPSTE24 Produkte

(Zinc Metalloproteinase, Ste24 (Zmpste24))
This gene encodes a member of the peptidase M48A family. The encoded protein is a zinc metalloproteinase involved in the two step post-translational proteolytic cleavage of carboxy terminal residues of farnesylated prelamin A to form mature lamin A. Mutations in this gene have been associated with mandibuloacral dysplasia and restrictive dermopathy. [provided by RefSeq, Jul 2008].

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Ausgewählte ZMPSTE24 Kategorien

ZMPSTE24 Antikörper

High quality antibodies with extensive validation data.

ZMPSTE24 ELISA Kits

Reliable ELISA kits for a wide range of species.

ZMPSTE24 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene ZMPSTE24 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation ELISA, IHC, IF
Validierungen
  • (3)
Kat. Nr. ABIN7146178
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, IHC (p)
Validierungen
  • (3)
  • (2)
Kat. Nr. ABIN389048
Menge 400 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, IHC (p)
Validierungen
  • (2)
  • (2)
Kat. Nr. ABIN389049
Menge 400 μL
Datenblatt Datenblatt

Empfohlene ZMPSTE24 ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method
Validierungen
Kat. Nr. ABIN1124570
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Mouse
Analytical Method
Validierungen
Kat. Nr. ABIN1124571
Menge 96 tests
Datenblatt Datenblatt

Empfohlene ZMPSTE24 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1325831
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1325829
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Tobacco (Nicotiana tabacum)
Validierungen
Kat. Nr. ABIN3110846
Menge 1 mg
Datenblatt Datenblatt

Neueste Publikationen zu unseren ZMPSTE24 Produkten

Akinci, Sankella, Gilpin, Ozono, Garg, Agarwal: "Progeroid syndrome patients with ZMPSTE24 deficiency could benefit when treated with rapamycin and dimethylsulfoxide." in: Cold Spring Harbor molecular case studies, Vol. 3, Issue 1, pp. a001339, (2017) (PubMed).

Afonso, Auclair, Boccara, Vantyghem, Katlama, Capeau, Vigouroux, Caron-Debarle: "LMNA mutations resulting in lipodystrophy and HIV protease inhibitors trigger vascular smooth muscle cell senescence and calcification: Role of ZMPSTE24 downregulation." in: Atherosclerosis, Vol. 245, pp. 200-11, (2016) (PubMed).

Ponnusamy, Zhang, Kadam, Lin, Lim, Sandhu, Kothandaraman, Mahyuddin, Biswas, Venkat, Hew, Joshi, Chung, Choolani: "Membrane proteins of human fetal primitive nucleated red blood cells." in: Journal of proteomics, Vol. 75, Issue 18, pp. 5762-73, (2012) (PubMed).

Fontaine-Bisson, Alessi, Saut, Fumeron, Marre, Dutour, Badens, Levy, Tichet, Juhan-Vague, Trégouët, Balkau, Morange: "Polymorphisms of the lamina maturation pathway and their association with the metabolic syndrome: the DESIR prospective study." in: Journal of molecular medicine (Berlin, Germany), Vol. 88, Issue 2, pp. 193-201, (2010) (PubMed).

Bailey, Xie, Do, Montpetit, Diaz, Mohan, Keavney, Yusuf, Gerstein, Engert, Anand: "Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study." in: Diabetes Care, Vol. 33, Issue 10, pp. 2250-3, (2010) (PubMed).

Talmud, Drenos, Shah, Shah, Palmen, Verzilli, Gaunt, Pallas, Lovering, Li, Casas, Sofat, Kumari, Rodriguez, Johnson, Newhouse, Dominiczak, Samani, Caulfield, Sever, Stanton, Shields, Padmanabhan et al.: "Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip. ..." in: American journal of human genetics, Vol. 85, Issue 5, pp. 628-42, (2009) (PubMed).

Coffinier, Hudon, Farber, Chang, Hrycyna, Young, Fong: "HIV protease inhibitors block the zinc metalloproteinase ZMPSTE24 and lead to an accumulation of prelamin A in cells." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 104, Issue 33, pp. 13432-7, (2007) (PubMed).

Fong, Frost, Meta, Qiao, Yang, Coffinier, Young: "A protein farnesyltransferase inhibitor ameliorates disease in a mouse model of progeria." in: Science (New York, N.Y.), Vol. 311, Issue 5767, pp. 1621-3, (2006) (PubMed).

Young, Fong, Michaelis: "Prelamin A, Zmpste24, misshapen cell nuclei, and progeria--new evidence suggesting that protein farnesylation could be important for disease pathogenesis." in: Journal of lipid research, Vol. 46, Issue 12, pp. 2531-58, (2005) (PubMed).

Corrigan, Kuszczak, Rusinol, Thewke, Hrycyna, Michaelis, Sinensky: "Prelamin A endoproteolytic processing in vitro by recombinant Zmpste24." in: The Biochemical journal, Vol. 387, Issue Pt 1, pp. 129-38, (2005) (PubMed).

Synonyme und alternative Namen zu ZMPSTE24

zinc metallopeptidase STE24 (ZMPSTE24), zinc metallopeptidase STE24 L homeolog (zmpste24.L), zinc metallopeptidase STE24 (zmpste24), CAAX prenyl protease (zmpste24), Peptidase family M48 family protein (ATSTE24), zinc metallopeptidase STE24 (Zmpste24), zinc metallopeptidase, STE24 (Zmpste24), zinc metallopeptidase, STE24 homolog (zmpste24), A530043O15Rik, D030046F19, DDBDRAFT_0189115, DDBDRAFT_0237846, DDB_0189115, DDB_0237846, F2N1.21, F2N1_21, FACE-1, Face-1, FACE1, fi45a02, HGPS, MADB, PRO1, STE24, Ste24p, wu:fi45a02, zgc:55655

Bezeichner auf Proteinebene für ZMPSTE24

  • zinc metallopeptidase (STE24 homolog, S. cerevisiae)
  • zinc metallopeptidase (STE24 homolog)
  • zinc metallopeptidase STE24 homolog
  • zinc metalloproteinase STE24 homolog
  • CAAX prenyl protease 1 homolog
  • STE24 endopeptidase
  • zinc metalloproteinase
  • zinc metallopeptidase STE24
  • CAAX prenyl protease 1 homolog-like
  • farnesylated proteins-converting enzyme 1
  • prenyl protein-specific endoprotease 1
  • zinc metalloproteinase Ste24 homolog
  • zinc metallopeptidase, STE24 homolog
  • zinc metalloproteinase, STE24 homolog
  • farnesylated-proteins converting enzyme 1
  • zinc metalloproteinase (STE24 homolog, yeast)
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