ZYX Produkte
(Zyxin (ZYX))
Kategorien
Focal adhesions are actin-rich structures that enable cells to adhere to the extracellular matrix and at which protein complexes involved in signal transduction assemble. Zyxin is a zinc-binding phosphoprotein that concentrates at focal adhesions and along the actin cytoskeleton. Zyxin has an N-terminal proline-rich domain and three LIM domains in its C-terminal half. The proline-rich domain may interact with SH3 domains of proteins involved in signal transduction pathways while the LIM domains are likely involved in protein-protein binding. Zyxin may function as a messenger in the signal transduction pathway that mediates adhesion-stimulated changes in gene expression and may modulate the cytoskeletal organization of actin bundles. Alternative splicing results in multiple transcript variants that encode the same isoform. [provided by RefSeq, Jul 2008].
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Ausgewählte ZYX Kategorien
ZYX Antikörper
High quality antibodies with extensive validation data.
ZYX ELISA Kits
Reliable ELISA kits for a wide range of species.
ZYX Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene ZYX Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IF, IP, RNAi
Validierungen
- (2)
- (6)
Kat. Nr.
ABIN563471
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IHC (p)
Validierungen
- (1)
- (4)
Kat. Nr.
ABIN521634
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human, Mouse, Rat
Applikation
WB, ELISA, IHC, IF, ICC
Validierungen
- (5)
Kat. Nr.
ABIN6266149
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene ZYX ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6975027
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6960598
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Mouse
Analytical Method
Validierungen
Kat. Nr.
ABIN1168973
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene ZYX Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
- (1)
Kat. Nr.
ABIN7125821
Menge
50 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1326572
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
Kat. Nr.
ABIN7396079
Menge
100 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren ZYX Produkten
: "Substrate engagement of integrins α5β1 and αvβ3 is necessary, but not sufficient, for high directional persistence in migration on fibronectin." in: Scientific reports, Vol. 6, pp. 23258, (2016) (PubMed).: "NBR1 enables autophagy-dependent focal adhesion turnover." in: The Journal of cell biology, Vol. 212, Issue 5, pp. 577-90, (2016) (PubMed).
: "α-Actinin-4 enhances colorectal cancer cell invasion by suppressing focal adhesion maturation." in: PLoS ONE, Vol. 10, Issue 4, pp. e0120616, (2015) (PubMed).
: "Cell shape-dependent early responses of fibroblasts to cyclic strain." in: Biochimica et biophysica acta, Vol. 1833, Issue 12, pp. 3415-25, (2013) (PubMed).
: "Zyxin is a transforming growth factor-? (TGF-?)/Smad3 target gene that regulates lung cancer cell motility via integrin ?5?1." in: The Journal of biological chemistry, Vol. 287, Issue 37, pp. 31393-405, (2012) (PubMed).
: "Cell-penetrating peptides with intracellular actin-remodeling activity in malignant fibroblasts." in: The Journal of biological chemistry, Vol. 285, Issue 10, pp. 7712-21, (2010) (PubMed).
: "Domain analysis of alpha-actinin reveals new aspects of its association with F-actin during cytokinesis." in: Experimental cell research, Vol. 316, Issue 12, pp. 1925-34, (2010) (PubMed).
: "Zyxin mediates actin fiber reorganization in epithelial-mesenchymal transition and contributes to endocardial morphogenesis." in: Molecular biology of the cell, Vol. 20, Issue 13, pp. 3115-24, (2009) (PubMed).
: "mTOR regulates expression of slit diaphragm proteins and cytoskeleton structure in podocytes." in: American journal of physiology. Renal physiology, Vol. 296, Issue 2, pp. F418-26, (2009) (PubMed).
: "Targeted disruption of the mouse Lipoma Preferred Partner gene." in: Biochemical and biophysical research communications, Vol. 379, Issue 2, pp. 368-73, (2009) (PubMed).
Synonyme und alternative Namen zu ZYX
Zyxin (zyx-1), Zyxin (Zyx), zyxin (zyx), zyxin (ZYX), zyxin (EDI_201420), zyxin (Zyx), zyxin S homeolog (zyx.S), 9530098H06Rik, BcDNA:LD06023, CG32018, DLim-1, Dmel\\CG32018, DmLIM-1, ESP-2, HED-2, lim, Lim102EF, MGC145270, R75157, zgc:171680, ZYX, zyx, ZYX102, Zyx102, zyx102, Zyx102EF, zyxinBezeichner auf Proteinebene für ZYX
- ZYXin family member (zyx-1)
- CG32018-PA
- CG32018-PB
- CG32018-PG
- CG32018-PH
- Zyx-PA
- Zyx-PB
- Zyx-PG
- Zyx-PH
- Zyx102EF
- zyxin
- hypothetical protein LOC779718
- zyxin-2
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